Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells.
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The ubiquitin-proteasome system in spongiform degenerative disordersGrowth plate zonal microarray analysis shows upregulation of extracellular matrix genes and downregulation of metalloproteinases and cathepsins following irradiationLoss of heterozygosity on long arm of chromosome 22 in sporadic colorectal carcinomaApoptolidin: induction of apoptosis by a natural product.Differential effects of lactacystin on cytokine production in activated Jurkat cells and murine splenocytesBH3-only proteins in apoptosis and beyond: an overview.BIK, the founding member of the BH3-only family proteins: mechanisms of cell death and role in cancer and pathogenic processes.Apoptosis induction by Bid requires unconventional ubiquitination and degradation of its N-terminal fragment.Bortezomib: a review of its use in patients with multiple myeloma.On the role of proteasomes in cell biology and proteasome inhibition as a novel frontier in the development of immunosuppressants.The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegansTwo closely related ubiquitin C-terminal hydrolase isozymes function as reciprocal modulators of germ cell apoptosis in cryptorchid testis.Regulation of the DNA damage response by ubiquitin conjugation.The role of the ubiquitin/proteasome system in cellular responses to radiation.New agents in acute myeloid leukemia and other myeloid disorders.Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling.The emerging role of bortezomib in the treatment of indolent non-Hodgkin's and mantle cell lymphomas.Ubiquitin ligases in malignant lymphoma.Combining proteasome inhibition with TNF-related apoptosis-inducing ligand (Apo2L/TRAIL) for cancer therapy.Treatment of mantle cell lymphoma: targeting the microenvironment.Targeting the proteasome in mantle cell lymphoma: a promising therapeutic approach.BCL2 family of apoptosis-related genes: functions and clinical implications in cancer.Chemical genetics: exploring the role of the proteasome in cell biology using natural products and other small molecule proteasome inhibitors.Ubiquitin ligases in cancer: ushers for degradation.Apoptotic and non-apoptotic programmed cardiomyocyte death in ventricular remodelling.Upregulation of proteasome activity rescues cardiomyocytes following pulse treatment with a proteasome inhibitor.Pharmacological modulation of anti-tumor immunity induced by oncolytic viruses.Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics.The increase in BIK expression following ERK1/2 pathway inhibition is a consequence of G₁ cell-cycle arrest and not a direct effect on BIK protein stability.Src tyrosine kinase inhibits apoptosis through the Erk1/2- dependent degradation of the death accelerator Bik.Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors.Evidence for involvement of BH3-only proapoptotic members in adenovirus-induced apoptosis.Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.Role of Bim in the survival pathway induced by Raf in epithelial cells.Activation of Bak, Bax, and BH3-only proteins in the apoptotic response to doxorubicin.Induction and endoplasmic reticulum location of BIK/NBK in response to apoptotic signaling by E1A and p53.Cannabinoid receptor agonist protects cultured dopaminergic neurons from the death by the proteasomal dysfunction.Phase 1 trial of bortezomib plus R-CHOP in previously untreated patients with aggressive non-Hodgkin lymphoma.Conformational change and mitochondrial translocation of Bax accompany proteasome inhibitor-induced apoptosis of chronic lymphocytic leukemic cells.
P2860
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P2860
Proteasomes modulate balance among proapoptotic and antiapoptotic Bcl-2 family members and compromise functioning of the electron transport chain in leukemic cells.
description
2001 nî lūn-bûn
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2001 թուականի Մարտին հրատարակուած գիտական յօդուած
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2001 թվականի մարտին հրատարակված գիտական հոդված
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2001年の論文
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2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@ast
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@en
type
label
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@ast
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@en
prefLabel
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@ast
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@en
P2093
P1476
Proteasomes modulate balance a ...... sport chain in leukemic cells.
@en
P2093
Bertrand R
Chinnadurai G
Marshansky V
P304
P356
10.4049/JIMMUNOL.166.5.3130
P407
P577
2001-03-01T00:00:00Z