An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).
about
Cloning and DNA-binding properties of the rat pancreatic beta-cell-specific factor Nkx6.1Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalonCross-talk between glucocorticoid and retinoic acid signals involving glucocorticoid receptor interaction with the homoeodomain protein Pbx1Transcriptional repression of peri-implantation EMX2 expression in mammalian reproduction by HOXA10PBX and MEIS as non-DNA-binding partners in trimeric complexes with HOX proteinsTrimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activityHOXA9 forms triple complexes with PBX2 and MEIS1 in myeloid cellsMissense mutations in the insulin promoter factor-1 gene predispose to type 2 diabetesGenomewide pharmacogenomic study of metabolic side effects to antipsychotic drugsPancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentSwertisin an Anti-Diabetic Compound Facilitate Islet Neogenesis from Pancreatic Stem/Progenitor Cells via p-38 MAP Kinase-SMAD Pathway: An In-Vitro and In-Vivo StudyThe homeodomain proteins PBX and MEIS1 are accessory factors that enhance thyroid hormone regulation of the malic enzyme gene in hepatocytesMembers of the large Maf transcription family regulate insulin gene transcription in islet beta cellsSubcellular localization of multiple PREP2 isoforms is regulated by actin, tubulin, and nuclear exportPDX:PBX complexes are required for normal proliferation of pancreatic cells during developmentPancreatic homeodomain transcription factor IDX1/IPF1 expressed in developing brain regulates somatostatin gene transcription in embryonic neural cellsRole of intrinsic DNA binding specificity in defining target genes of the mammalian transcription factor PDX1Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotypeMeis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesisThe PDX1 homeodomain transcription factor negatively regulates the pancreatic ductal cell-specific keratin 19 promoterDNA binding and transcriptional activation by a PDX1.PBX1b.MEIS2b trimer and cooperation with a pancreas-specific basic helix-loop-helix complexChanges in HOXB6 homeodomain protein structure and localization during human epidermal development and differentiationA feat of metabolic proportions: Pdx1 orchestrates islet development and function in the maintenance of glucose homeostasis.TALE homeodomain proteins regulate gonadotropin-releasing hormone gene expression independently and via interactions with Oct-1.Purification of the Prep1 interactome identifies novel pathways regulated by Prep1.Evaluating the association of common PBX1 variants with type 2 diabetes.Expression of zebrafish pax6b in pancreas is regulated by two enhancers containing highly conserved cis-elements bound by PDX1, PBX and PREP factorsEpistemology of the origin of cancer: a new paradigm.Gene expression in pancreatic adenocarcinoma.Pdx1 inactivation restricted to the intestinal epithelium in mice alters duodenal gene expression in enterocytes and enteroendocrine cells.Locus co-occupancy, nucleosome positioning, and H3K4me1 regulate the functionality of FOXA2-, HNF4A-, and PDX1-bound loci in islets and liverExperimental control of pancreatic development and maintenance.Hox genes and their candidate downstream targets in the developing central nervous system.PDX-1: demonstration of oncogenic properties in pancreatic cancer.Context-dependent transformation of adult pancreatic cells by oncogenic K-Ras.Undervalued criteria in the evaluation of multimodal trials for upper GI cancers.Binding polymorphism in the DNA bound state of the Pdx1 homeodomainNovel monoclonal antibodies against Pdx1 reveal feedback regulation of Pdx1 protein levels.Development of cell markers for the identification and expansion of islet progenitor cells.Prototypic and arkypallidal neurons in the dopamine-intact external globus pallidus.
P2860
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P2860
An endocrine-exocrine switch in the activity of the pancreatic homeodomain protein PDX1 through formation of a trimeric complex with PBX1b and MRG1 (MEIS2).
description
1998 nî lūn-bûn
@nan
1998 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@ast
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@en
type
label
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@ast
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@en
prefLabel
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@ast
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@en
P2093
P2860
P356
P1476
An endocrine-exocrine switch i ...... x with PBX1b and MRG1 (MEIS2).
@en
P2093
A M Buchberg
C V Wright
L J Bischof
R J MacDonald
S Steelman
P2860
P304
P356
10.1128/MCB.18.9.5109
P407
P577
1998-09-01T00:00:00Z