Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches. - Wikidata - awgldk - TriplyDB

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches.

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches.

http://www.wikidata.org/entity/Q32052639

about

Mechanisms of acetaminophen-induced liver necrosis The National Center for Toxicogenomics: using new technologies to inform mechanistic toxicology.Novel in vitro and mathematical models for the prediction of chemical toxicity Multi-Organ toxicity demonstration in a functional human in vitro system composed of four organs.Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line.Evidence-based selection of training compounds for use in the mechanism-based integrated prediction of drug-induced liver injury in man Evidence of reduced oral bioavailability of paracetamol in rats following multiple ingestion of grapefruit juice Humanizing π-class glutathione S-transferase regulation in a mouse model alters liver toxicity in response to acetaminophen overdose The roles of myeloperoxidase in coronary artery disease and its potential implication in plaque rupture.Application of toxicogenomics to toxicology: basic concepts in the analysis of microarray data.Chrysin Protects Rat Kidney from Paracetamol-Induced Oxidative Stress, Inflammation, Apoptosis, and Autophagy: A Multi-Biomarker Approach An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity.The dual role of osteopontin in acetaminophen hepatotoxicity Acetaminophen inhibits hemoprotein-catalyzed lipid peroxidation and attenuates rhabdomyolysis-induced renal failure.PROTECTIVE EFFECT OF MORINGA PEREGRINA LEAVES EXTRACT ON ACETAMINOPHEN -INDUCED LIVER TOXICITY IN ALBINO RATS.Proteomics investigations of drug-induced hepatotoxicity in HepG2 cells.Myeloperoxidase-derived oxidation: mechanisms of biological damage and its prevention Buccal acetaminophen provides fast analgesia: two randomized clinical trials in healthy volunteers.Aloe vera attenuated liver injury in mice with acetaminophen-induced hepatitis.Effects of imatinib mesylate on the pharmacokinetics of paracetamol (acetaminophen) in Korean patients with chronic myelogenous leukaemia.Acetaminophen-induced nephrotoxicity: pathophysiology, clinical manifestations, and management.Acute interstitial nephritis with acetaminophen and alcohol intoxication.Acetaminophen hepatotoxicity and HIF-1α induction in acetaminophen toxicity in mice occurs without hypoxia.Profiling the reactive metabolites of xenobiotics using metabolomic technologies Protective effects of 2,4-dihydroxybenzophenone against acetaminophen-induced hepatotoxicity in mice Susceptibility to acetaminophen (APAP) toxicity unexpectedly is decreased during acute viral hepatitis in mice.Age-related changes in the hepatic pharmacology and toxicology of paracetamol.Characterizing protein modifications by reactive metabolites using magnetic bead bioreactors and LC-MS/MS Acetaminophen intoxication and length of treatment: how long is long enough?Preventive Effect of the Korean Traditional Health Drink (Taemyeongcheong) on Acetaminophen-Induced Hepatic Damage in ICR Mice.Changes in mouse liver protein glutathionylation after acetaminophen exposure.Cataract formation and prevention.PharmGKB summary: pathways of acetaminophen metabolism at the therapeutic versus toxic doses.Acetaminophen-induced hepatotoxicity: role of metabolic activation, reactive oxygen/nitrogen species, and mitochondrial permeability transition.Protective effects of 5-methoxypsoralen against acetaminophen-induced hepatotoxicity in mice.Drug bioactivation, covalent binding to target proteins and toxicity relevance.Over-the-Counter Monocyclic Non-Steroidal Anti-Inflammatory Drugs in Environment-Sources, Risks, Biodegradation.Formononetin protects against acetaminophen-induced hepatotoxicity through enhanced NRF2 activity.Risk of Acute Kidney Injury and Long-Term Outcome in Patients With Acetaminophen Intoxication: A Nationwide Population-Based Retrospective Cohort Study Acetaminophen cytotoxicity is ameliorated in a human liver organotypic co-culture model

P2860

Q24629891-5CD3E9FC-9400-4FD1-9E37-CFB4D1D35DE6 Q24815490-042D7BF0-27D4-44EF-AF6C-68FB6BA3D2A5 Q26851492-F445607D-308F-4EBE-AFCB-5D970F15E047 Q27300308-300499CA-EDAC-4693-976E-275FFF6F6CF7 Q27308057-8555F607-8246-4EEA-9DB2-B3057CA3C2F1 Q28069617-13355766-BAD7-4109-A15D-72F860E702A2 Q28254692-A4905DA5-294F-47A4-9DA4-CBD41DED9D83 Q28477445-2E06DC5F-D1CB-460A-B8FF-3431B64DFDCF Q30240734-E8F8A15D-ADB2-4394-A449-65EC028F6B6D Q30939430-929E2A15-C7A7-48D2-9019-8A93AFB60B03 Q33553296-7264C933-FB53-470E-BCD8-F62C12FAE5A3 Q33560256-A5506935-5F89-4A9F-B516-539CA0977DA6 Q33571322-C569D074-BA7C-4396-8E3D-31B55383041B Q33664612-5DED5055-4E6A-4703-A391-F50D3EB0F351 Q33732884-73A50BD7-FF87-47F4-925C-A8B818C1F936 Q33773197-4CAE50DE-10B6-4369-AF37-16CC40528795 Q34162955-7BC1E50C-BD0B-4549-8692-F08AEDD8E3DA Q34442805-B3C59776-407C-4BC1-BE60-C11664FE7F4F Q34485517-5529C68A-2E8A-4ED6-8DA2-65F024EE8DA1 Q34580581-6FFAD2A7-4941-4434-B40E-9894F356ED7B Q34761408-822AFD3E-CAE0-4D24-8146-982A54206BF2 Q34980537-359AE5F0-9AED-4F55-8F87-9DBFAFF71293 Q34997326-0211E8DC-02C9-486B-B03D-046CCE9FED75 Q35001524-F20EFD1E-FA24-48FB-AA87-7D1DBAE9EEAA Q35033821-4F17943F-53BE-4AE8-830C-9BA6307B5E28 Q35080126-C49277C2-9B16-4FB2-8650-AA9942E4FFE9 Q35101500-94CC7CA5-1A6A-48D3-9E21-DF3BC709DD98 Q35142968-93B09407-9A2C-4FE0-BC26-811314D0DFCC Q35200882-E886BF8B-D628-4A34-BC76-447D1FED95F3 Q35342293-65EF7E56-4292-46B4-9F96-1BA39FBEDA94 Q35688553-F83A98D6-AF03-4685-8BF1-9564618677F7 Q35790808-2A35CAE4-13BA-4D04-80E8-AF7048C8EFEC Q35842112-4394A975-7470-4749-951E-B7F75456AE75 Q35956222-07904929-9401-4174-A704-02EA79C2407A Q35958234-390CF869-4953-42B3-B6B4-74D67095326E Q36061821-67A471E0-C253-47E1-BA96-4787173C3A52 Q36143557-3DB44249-319E-49AF-A596-E22FA36954E9 Q36289550-E3F0ADD7-113B-472C-ADDA-1AAE17BA8AB4 Q36299290-F3C551CD-96E6-416F-A5D7-643E7A7ECDEA Q36343336-633C1999-C9B4-46CF-8FC5-78D705F3644A

P2860

Paracetamol (acetaminophen)-induced toxicity: molecular and biochemical mechanisms, analogues and protective approaches.

http://www.wikidata.org/entity/Q32052639

description

2001 nî lūn-bûn

@nan

2001 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2001年の論文

@ja

2001年論文

@yue

2001年論文

@zh-hant

2001年論文

@zh-hk

2001年論文

@zh-mo

2001年論文

@zh-tw

2001年论文

@wuu

name

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@ast

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@en

type

label

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@ast

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@en

prefLabel

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@ast

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@en

P1433

Q32052639-49E49BED-EC74-440C-B2CB-42A6466D93CD

P1476

Q32052639-0D852EB4-DE99-4121-B262-BB0D805A657B

P2093

Q32052639-167CD036-ECD9-4DAE-A522-04892AA624A8

Q32052639-96092A31-F7FD-48CF-93B9-27B04F3485F6

P2860

Q32052639-00756798-29B9-443C-9D93-BC2F77859ABE

Q32052639-017B2546-F697-4520-8B01-6172E8864DF1

Q32052639-01AF62C1-2CEB-4C20-A0F5-B3BF6169875A

Q32052639-039CAAD0-1124-4AA3-B6B3-7AFB432797A4

Q32052639-09E84D1C-7066-4A25-9B40-EAC3F1D63C88

Q32052639-0B1A9A82-1D05-4D98-AA83-C0FE50A0FD34

Q32052639-0C1D10FB-4705-4C80-918E-957102C93490

Q32052639-112F5EA9-E878-4E57-A725-5CC3ED993CD1

Q32052639-12839A08-236C-4C0D-A54D-02913F728D4B

Q32052639-17B8D9F4-0AA3-4D4A-BFAE-AAC463916FD8

P304

Q32052639-30971F2A-38CD-42E3-8894-F6D962C8213F

P31

Q32052639-6E2BC570-0AC5-4DD3-9DF7-F1FDE1D4EFF0

P356

Q32052639-9086850F-9453-4426-99E5-A777FEFEFAE2

P407

Q32052639-92684627-9C9C-45EF-B21A-CE9793779034

P433

Q32052639-687A17DA-77BE-4238-BD7E-5770B5FECF99

P478

Q32052639-B3341C6B-AD59-4E3B-A262-3A50F9FD6D14

P577

Q32052639-3B35DD50-ECF9-4174-B5BC-CDE7CC037792

P5875

Q32052639-02EC78CD-4CED-40FA-A2AE-738D35C40F77

P698

Q32052639-E0D66360-8DD9-430D-A4C3-B70EEE6746E8

P356

P1433

Critical Reviews in Toxicology

P1476

Paracetamol (acetaminophen)-in ...... ues and protective approaches.

@en

P2093

J G Bessems

http://www.w3.org/2001/XMLSchema#string

N P Vermeulen

http://www.w3.org/2001/XMLSchema#string

P2860

Positional isomers of acetaminophen differentially induce proliferation of cultured breast cancer cells.

The structure of a complex of hexameric insulin and 4'-hydroxyacetanilide

N-acetyl-p-benzoquinone imine: a cytochrome P-450-mediated oxidation product of acetaminophen

A metabolite of acetaminophen covalently binds to the 56 kDa selenium binding protein

Nephrotoxicity of paracetamol in the rat--mechanistic and therapeutic aspects

Decreased glucuronidation and increased bioactivation of acetaminophen in Gilbert's syndrome

Evidence against deacetylation and for cytochrome P450-mediated activation in acetaminophen-induced nephrotoxicity in the CD-1 mouse

Free-radical metabolites of acetaminophen and a dimethylated derivative

DNA sequencing of a mouse liver protein that binds selenium: implications for selenium's mechanism of action in cancer prevention

The mechanism of prevention of paracetamol-induced hepatotoxicity by 3,5-dialkyl substitution

P304

55-138

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1080/20014091111677

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

31

http://www.w3.org/2001/XMLSchema#string

P577

2001-01-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

12115059

http://www.w3.org/2001/XMLSchema#string

P698

11215692

http://www.w3.org/2001/XMLSchema#string