Cloning and expression of a group IV cytosolic Ca2+-dependent phospholipase A2 from rat pancreatic islets. Comparison of the expressed activity with that of an islet group VI cytosolic Ca2+-independent phospholipase A2.
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Human Pancreatic Islets Express mRNA Species Encoding Two Distinct Catalytically Active Isoforms of Group VI Phospholipase A2 (iPLA2) [etc.]The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2beta) in beta-cellsCharacterization of FKGK18 as inhibitor of group VIA Ca2+-independent phospholipase A2 (iPLA2β): candidate drug for preventing beta-cell apoptosis and diabetesPancreatic islets and insulinoma cells express a novel isoform of group VIA phospholipase A2 (iPLA2 beta) that participates in glucose-stimulated insulin secretion and is not produced by alternate splicing of the iPLA2 beta transcriptEvidence for proteolytic processing and stimulated organelle redistribution of iPLA(2)beta.Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Inhibition of Ca2+-independent phospholipase A2 results in insufficient insulin secretion and impaired glucose tolerance.Islet complex lipids: involvement in the actions of group VIA calcium-independent phospholipase A(2) in beta-cellsCalcium-independent phospholipases A2 and their roles in biological processes and diseases.Insulin secretory responses and phospholipid composition of pancreatic islets from mice that do not express Group VIA phospholipase A2 and effects of metabolic stress on glucose homeostasis.Attenuated free cholesterol loading-induced apoptosis but preserved phospholipid composition of peritoneal macrophages from mice that do not express group VIA phospholipase A2.Effects of stable suppression of Group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells.Male mice that do not express group VIA phospholipase A2 produce spermatozoa with impaired motility and have greatly reduced fertility.Calcium-independent phospholipases in the heart: mediators of cellular signaling, bioenergetics, and ischemia-induced electrophysiologic dysfunctionAnalyses of Calcium-Independent Phospholipase A2beta (iPLA2β) in Biological Systems.Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer.A bromoenol lactone suicide substrate inactivates group VIA phospholipase A2 by generating a diffusible bromomethyl keto acid that alkylates cysteine thiolsA new pathway for glucose-dependent insulinotropic polypeptide (GIP) receptor signaling: evidence for the involvement of phospholipase A2 in GIP-stimulated insulin secretion.Effects of biological oxidants on the catalytic activity and structure of group VIA phospholipase A2Cell swelling-induced signaling for insulin secretion bypasses steps involving G proteins and PLA2 and is N-ethylmaleimide insensitive.cPLA2alpha-evoked formation of arachidonic acid and lysophospholipids is required for exocytosis in mouse pancreatic beta-cells.STAT-3-dependent cytosolic phospholipase A2 expression is required for thrombin-induced vascular smooth muscle cell motility.Activation of cytosolic phospholipase A2 and fatty acid transacylase is essential but not sufficient for thrombin-induced smooth muscle cell proliferation.One-step purification of functional human and rat pancreatic alpha cells.
P2860
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P2860
Cloning and expression of a group IV cytosolic Ca2+-dependent phospholipase A2 from rat pancreatic islets. Comparison of the expressed activity with that of an islet group VI cytosolic Ca2+-independent phospholipase A2.
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Cloning and expression of a gr ...... -independent phospholipase A2.
@ast
Cloning and expression of a gr ...... -independent phospholipase A2.
@en
type
label
Cloning and expression of a gr ...... -independent phospholipase A2.
@ast
Cloning and expression of a gr ...... -independent phospholipase A2.
@en
prefLabel
Cloning and expression of a gr ...... -independent phospholipase A2.
@ast
Cloning and expression of a gr ...... -independent phospholipase A2.
@en
P2093
P1476
Cloning and expression of a gr ...... -independent phospholipase A2.
@en
P2093
P304
P356
10.1016/S0005-2760(98)00027-7
P407
P577
1998-04-01T00:00:00Z