Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: implications for AIDS pathology
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The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition poreNovel properties of the protein kinase CK2-site-regulated nuclear- localization sequence of the interferon-induced nuclear factor IFI 16Analysis of HIV-1 Vpr determinants responsible for cell growth arrest in Saccharomyces cerevisiaeMonocytes as regulators of inflammation and HIV-related comorbidities during cARTHIV-1 Vpr induces apoptosis through caspase 9 in T cells and peripheral blood mononuclear cellsThe C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathwayHuman immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanismFunctional and structural characterization of synthetic HIV-1 Vpr that transduces cells, localizes to the nucleus, and induces G2 cell cycle arrest.The amino-terminal region of Vpr from human immunodeficiency virus type 1 forms ion channels and kills neurons.Hepatitis C virus core protein induces neuroimmune activation and potentiates Human Immunodeficiency Virus-1 neurotoxicityMolecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review.Methamphetamine abuse, HIV infection, and neurotoxicity.Genetic variation and HIV-associated neurologic disease.Short communication: circulating plasma HIV-1 viral protein R in dual HIV-1/tuberculosis infectionInteractions of human immunodeficiency virus-1 proteins with neurons: possible role in the development of human immunodeficiency virus-1-associated dementia.Potassium ion channels of Chlorella viruses cause rapid depolarization of host cells during infection.In vitro and animal models of human immunodeficiency virus infection of the central nervous systemThe progestin-only contraceptive medroxyprogesterone acetate, but not norethisterone acetate, enhances HIV-1 Vpr-mediated apoptosis in human CD4+ T cells through the glucocorticoid receptor.HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic interventionHIV-1 neuropathogenesis: glial mechanisms revealed through substance abusePossible function for virus encoded K+ channel Kcv in the replication of chlorella virus PBCV-1.Creatine pretreatment protects cortical axons from energy depletion in vitro.Extracellular human immunodeficiency virus type 1 viral protein R causes reductions in astrocytic ATP and glutathione levels compromising the antioxidant reservoir.HIV-1 infection and AIDS: consequences for the central nervous system.HIV's double strike at the brain: neuronal toxicity and compromised neurogenesis.HIV and apoptosis death and the mitochondrion.Extracellular HIV-1 viral protein R affects astrocytic glyceraldehyde 3-phosphate dehydrogenase activity and neuronal survival.Human immunodeficiency virus viral protein R as an extracellular protein in neuropathogenesis.Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic developmentHost and viral factors influencing the pathogenesis of HIV-associated neurocognitive disorders.Novel neuroprotective GSK-3β inhibitor restricts Tat-mediated HIV-1 replication.Astrocytic expression of HIV-1 viral protein R in the hippocampus causes chromatolysis, synaptic loss and memory impairment.Neuronal Stress and Injury Caused by HIV-1, cART and Drug Abuse: Converging Contributions to HAND.Infectious agents and neurodegeneration.HIV1-viral protein R (Vpr) mutations: associated phenotypes and relevance for clinical pathologies.The HIV-1 Vpr Protein: A Multifaceted Target for Therapeutic Intervention.Human immunodeficiency virus type 1 Vpr induces apoptosis in human neuronal cells.Virion-associated Vpr of human immunodeficiency virus type 1 triggers activation of apoptotic events and enhances fas-induced apoptosis in human T cells.Activation of JNK-dependent pathway is required for HIV viral protein R-induced apoptosis in human monocytic cells: involvement of antiapoptotic BCL2 and c-IAP1 genes.HIV-1 Viral Protein R Activates NLRP3 Inflammasome in Microglia: implications for HIV-1 Associated Neuroinflammation.
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P2860
Extracellular HIV-1 virus protein R causes a large inward current and cell death in cultured hippocampal neurons: implications for AIDS pathology
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
name
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@ast
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@en
type
label
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@ast
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@en
prefLabel
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@ast
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@en
P2093
P2860
P921
P356
P1476
Extracellular HIV-1 virus prot ...... mplications for AIDS pathology
@en
P2093
P2860
P304
P356
10.1073/PNAS.95.8.4595
P407
P577
1998-04-01T00:00:00Z