Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632.
about
Noncanonical Wnt11 inhibits hepatocellular carcinoma cell proliferation and migrationDistinct temporal-spatial roles for rho kinase and myosin light chain kinase in epithelial purse-string wound closure.Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasionRho-associated kinase signalling and the cancer microenvironment: novel biological implications and therapeutic opportunitiesApproaches of targeting Rho GTPases in cancer drug discoveryRegulation of ROCK activity in cancerCrosstalk between Inflammation and ROCK/MLCK Signaling Pathways in Gastrointestinal Disorders with Intestinal HyperpermeabilityRole of DLC1 tumor suppressor gene and MYC oncogene in pathogenesis of human hepatocellular carcinoma: potential prospects for combined targeted therapeutics (review)Higher LPA2 and LPA6 mRNA Levels in Hepatocellular Carcinoma Are Associated with Poorer Differentiation, Microvascular Invasion and Earlier Recurrence with Higher Serum Autotaxin LevelsDeleted in liver cancer 1 (DLC1) negatively regulates Rho/ROCK/MLC pathway in hepatocellular carcinomaDynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion eventsMigrastatics-Anti-metastatic and Anti-invasion Drugs: Promises and Challenges.Cytoplasmic expression of p27(kip1) is associated with a favourable prognosis in colorectal cancer patients.Rho/ROCK signaling in motility and metastasis of gastric cancerRho kinase phosphorylation promotes ezrin-mediated metastasis in hepatocellular carcinoma.A novel animal model for in vivo study of liver cancer metastasis.Inhibition of Rho-associated coiled-coil-forming kinase increases efficacy of measles virotherapy.The ROCK signaling and breast cancer metastasis.Lysophosphatidic acid (LPA) signalling in cell migration and cancer invasion: a focussed review and analysis of LPA receptor gene expression on the basis of more than 1700 cancer microarrays.Rho kinase inhibitors: a patent review (2012 - 2013).Fatty liver creates a pro-metastatic microenvironment for hepatocellular carcinoma through activation of hepatic stellate cells.Do fasudil and Y-27632 affect the level of transient receptor potential (TRP) gene expressions in breast cancer cell lines?RhoE is frequently down-regulated in hepatocellular carcinoma (HCC) and suppresses HCC invasion through antagonizing the Rho/Rho-kinase/myosin phosphatase target pathway.The Rho kinase inhibitor fasudil is involved in p53-mediated apoptosis in human hepatocellular carcinoma cells.RhoE/ROCK2 regulates chemoresistance through NF-κB/IL-6/ STAT3 signaling in hepatocellular carcinoma.HA1077, a Rho kinase inhibitor, suppresses glioma-induced angiogenesis by targeting the Rho-ROCK and the mitogen-activated protein kinase kinase/extracellular signal-regulated kinase (MEK/ERK) signal pathways.F-actin reorganization and inactivation of rho signaling pathway involved in the inhibitory effect of Coptidis Rhizoma on hepatoma cell migration.Effect of fasudil on growth, adhesion, invasion, and migration of 95D lung carcinoma cells in vitro.STAT5a activation mediates the epithelial to mesenchymal transition induced by oncogenic RhoARho-kinase 2 is frequently overexpressed in hepatocellular carcinoma and involved in tumor invasion.Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model.MEK/ERK signaling is a critical mediator for integrin-induced cell scattering in highly metastatic hepatocellular carcinoma cells.Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1.Expression of somatostatin receptors in normal and cirrhotic human liver and in hepatocellular carcinoma.Possible involvement of tetraspanin CO-029 in hematogenous intrahepatic metastasis of liver cancer cells.Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor.Myosin phosphatase and RhoA-activated kinase modulate arginine methylation by the regulation of protein arginine methyltransferase 5 in hepatocellular carcinoma cells.Afzelin exhibits anti-cancer activity against androgen-sensitive LNCaP and androgen-independent PC-3 prostate cancer cells through the inhibition of LIM domain kinase 1.Gene expression alteration during redox-dependent enhancement of arsenic cytotoxicity by emodin in HeLa cells.Overexpression of a disintegrin and metalloproteinase 21 is associated with motility, metastasis, and poor prognosis in hepatocellular carcinoma.
P2860
Q24297486-622BCB0C-C1F8-4173-A050-C24EF73934BDQ24299983-8ED631CE-3A60-4EA9-BE7B-C04481FC84BAQ24338744-2ACD35CC-056B-4BA1-9A72-7D60E6A23361Q26778344-85D7B67A-4DF4-4B8D-857D-FE80ADB30885Q26851300-3659C5C7-D50C-43F0-A674-E3F76E3BA59DQ27006554-35927121-DF5C-4D0E-AA86-C687C4E12036Q28079482-F3220F84-936C-4258-A05C-43E39028EF43Q28394917-83B0681C-9A18-41C4-9E30-F0A1FA37C8BCQ29048613-C8220F3F-E5AC-446C-BA66-A28981960FB8Q33354161-37E9CC12-C991-4D23-BF43-1AE914044D3FQ33629153-7A116AF9-8E23-4029-9F9E-5DA7FF3450DDQ33828559-429F45F3-5A79-440F-B975-AF24390CC092Q33869104-E0B44558-530B-444A-8A08-FCDADB8AD2BDQ34326599-6D37FCBE-DDC3-4DF1-B778-15B7A25F11A6Q35056704-6CAA4503-8D09-4825-B6C6-DEC9B7DE3DCBQ36144512-DDCD72ED-1292-4D83-A025-465CFB15C8A1Q37520335-E89DD4A3-5726-443F-8931-41DF3EB3EFC3Q37770084-0A312B46-7BE0-4D58-B836-08418899B896Q38101074-024B0EBD-6FFC-444E-97EE-259FB0E2E26EQ38166844-31FE7696-74E0-42AD-8625-593C7E317591Q38972601-7EF9237D-B4F9-4F15-87A2-7A7AA62A255BQ38993976-179BE473-69C1-4404-B338-593B13C6A4EDQ39308679-C4FC20E4-DBAC-435E-9DAC-739C06FA6047Q39368544-79E26286-AD8C-4420-B183-BBAEC17F5C07Q39541068-E807E0FE-2951-46AC-83A1-0F0EB250204CQ39618849-B54F2FF1-060B-47BA-8FEE-C3A954B1860EQ39627908-D5A27057-97A0-4825-B7E9-7C8FE86B0712Q39648135-53D23BD5-4809-43C7-B220-A1C316603FEAQ39697053-449991A1-435B-4F1B-9568-B9FF7EDFB00FQ39885550-BA26E90C-8E19-43D2-A410-4A280FAC0765Q40182395-7F758307-644F-456A-AA91-C1E96E42DB95Q40287958-4C7A2DB8-35A3-4297-8C82-5D010E4CB854Q40478610-6AEA0674-A294-488D-AEC5-87052CBD84DAQ40537154-6ACF830E-16E2-4CE1-B0C9-9972AA52D874Q40627661-4BA91F34-58D9-4BD0-A999-8F016A2B7ABFQ40724768-33A0AC1B-B471-4DA4-A33C-69A1636E9C08Q41195266-0E0C9D03-325E-43FC-997A-B3599675D367Q43242562-10DEF79E-C634-48E6-A219-4AF09E301F06Q46620180-356A326D-755B-4937-A50F-EC1151B4A53CQ47099168-FA75747C-F3D1-416F-8655-4D18D4E64543
P2860
Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@ast
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@en
type
label
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@ast
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@en
prefLabel
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@ast
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@en
P2093
P356
P1433
P1476
Inhibition of intrahepatic met ...... tein kinase inhibitor Y-27632.
@en
P2093
P304
P356
10.1053/JHEP.2001.22652
P407
P577
2001-03-01T00:00:00Z