Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases.
about
Integrin signaling in neutrophils and macrophages uses adaptors containing immunoreceptor tyrosine-based activation motifsNeutrophil cell surface receptors and their intracellular signal transduction pathways.Activation of A2A adenosine receptors inhibits expression of alpha 4/beta 1 integrin (very late antigen-4) on stimulated human neutrophils.Integrin alpha4beta1 promotes focal adhesion kinase-independent cell motility via alpha4 cytoplasmic domain-specific activation of c-Src.Functional analysis of activating receptor LMIR4 as a counterpart of inhibitory receptor LMIR3.Apolipoprotein A-I mimetic 4F alters the function of human monocyte-derived macrophages.The Src family kinases Hck, Fgr, and Lyn are critical for the generation of the in vivo inflammatory environment without a direct role in leukocyte recruitmentNeutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: generation and analysis of a novel null mutation in mice.An anti-inflammatory role of VEGFR2/Src kinase inhibitor in herpes simplex virus 1-induced immunopathology.Overlapping roles of endothelial selectins and vascular cell adhesion molecule-1 in immune complex-induced leukocyte recruitment in the cremasteric microvasculature.Targeting Syk as a treatment for allergic and autoimmune disorders.Involvement of Src family tyrosine kinase in apoptosis of human neutrophils induced by protozoan parasite Entamoeba histolytica.Fes tyrosine kinase promotes survival and terminal granulocyte differentiation of factor-dependent myeloid progenitors (32D) and activates lineage-specific transcription factors.A very late activating antigen-alpha4 (CD49d) monoclonal antibody, BU49 induces phosphorylation of a cAMP response element-binding protein (CREB), resulting in induction of homotypic cell aggregation and enhancement of interleukin-8 (IL-8) productioUnique and redundant roles of alpha4 and beta2 integrins in kinetics of recruitment of lymphoid vs myeloid cell subsets to the inflamed peritoneum revealed by studies of genetically deficient mice.Strain-Related Differences in the Immune Response: Relevance to Human Stroke.Anti-alpha4beta1 integrin antibody induces receptor internalization and does not impair the function of circulating neutrophilic leukocytes.The role of selectins and integrins in adenovirus vector-induced neutrophil recruitment to the liver.Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.Endometrial gene expression in high- and low-fertility heifers in the late luteal phase of the estrous cycle and a comparison with midluteal gene expression.
P2860
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P2860
Resting murine neutrophils express functional alpha 4 integrins that signal through Src family kinases.
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Resting murine neutrophils exp ...... al through Src family kinases.
@ast
Resting murine neutrophils exp ...... al through Src family kinases.
@en
type
label
Resting murine neutrophils exp ...... al through Src family kinases.
@ast
Resting murine neutrophils exp ...... al through Src family kinases.
@en
prefLabel
Resting murine neutrophils exp ...... al through Src family kinases.
@ast
Resting murine neutrophils exp ...... al through Src family kinases.
@en
P2093
P1476
Resting murine neutrophils exp ...... nal through Src family kinases
@en
P2093
P304
P356
10.4049/JIMMUNOL.166.6.4115
P407
P577
2001-03-01T00:00:00Z