A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors.
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New treatment option for ovarian cancer: PARP inhibitorsTrial watch - inhibiting PARP enzymes for anticancer therapyHomologous Recombination Deficiency: Exploiting the Fundamental Vulnerability of Ovarian CancerOlaparib in the management of ovarian cancerPARP inhibitors in the management of breast cancer: current data and future prospectsIncreasing Superoxide Production and the Labile Iron Pool in Tumor Cells may Sensitize Them to Extracellular AscorbateNew perspectives on targeted therapy in ovarian cancerPARP inhibitor treatment in ovarian and breast cancerPhase I/Ib study of olaparib and carboplatin in BRCA1 or BRCA2 mutation-associated breast or ovarian cancer with biomarker analyses.Phase I study of olaparib in combination with liposomal doxorubicin in patients with advanced solid tumours.A phase 1 safety study of veliparib combined with cisplatin and etoposide in extensive stage small cell lung cancer: A trial of the ECOG-ACRIN Cancer Research Group (E2511).Phase I Study of Veliparib (ABT-888) Combined with Cisplatin and Vinorelbine in Advanced Triple-Negative Breast Cancer and/or BRCA Mutation-Associated Breast CancerA Phase I study of olaparib and irinotecan in patients with colorectal cancer: Canadian Cancer Trials Group IND 187.A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumoursPARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models.Enhancing synthetic lethality of PARP-inhibitor and cisplatin in BRCA-proficient tumour cells with hyperthermia.The PARP inhibitors, veliparib and olaparib, are effective chemopreventive agents for delaying mammary tumor development in BRCA1-deficient miceDevelopment of synthetic lethality anticancer therapeutics.Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer.Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer.Nivolumab and Olaparib.A DNA repair BRCA1 estrogen receptor and targeted therapy in breast cancer.Is there an epigenetic component underlying the resistance of triple-negative breast cancers to parp inhibitors?Therapeutic applications of PARP inhibitors: anticancer therapy and beyondOncogenic miR-181a/b affect the DNA damage response in aggressive breast cancer.Emerging treatment options for recurrent ovarian cancer: the potential role of olaparib.PARP Inhibitors in Reproductive System Cancers: Current Use and Developments.Phase I trial of the oral PARP inhibitor olaparib in combination with paclitaxel for first- or second-line treatment of patients with metastatic triple-negative breast cancer.Nitric oxide (NO) releasing poly ADP-ribose polymerase 1 (PARP-1) inhibitors targeted to glutathione S-transferase P1-overexpressing cancer cells.Olaparib, PARP1 inhibitor in ovarian cancer.Olaparib: a promising PARP inhibitor in ovarian cancer therapy.Predictive biomarkers for cancer therapy with PARP inhibitors.Appraising iniparib, the PARP inhibitor that never was--what must we learn?Management options in locally advanced pancreatic cancer.Olaparib: first global approval.Safety evaluation of olaparib for treating ovarian cancer.Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.Population pharmacokinetic analyses of the effect of carboplatin pretreatment on olaparib in recurrent or refractory women's cancers.Preliminary evaluation of prostate-targeted radiotherapy using (131) I-MIP-1095 in combination with radiosensitising chemotherapeutic drugs.A comprehensive look of poly(ADP-ribose) polymerase inhibition strategies and future directions for cancer therapy.
P2860
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P2860
A phase I combination study of olaparib with cisplatin and gemcitabine in adults with solid tumors.
description
2012 nî lūn-bûn
@nan
2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
A phase I combination study of ...... e in adults with solid tumors.
@ast
A phase I combination study of ...... e in adults with solid tumors.
@en
type
label
A phase I combination study of ...... e in adults with solid tumors.
@ast
A phase I combination study of ...... e in adults with solid tumors.
@en
prefLabel
A phase I combination study of ...... e in adults with solid tumors.
@ast
A phase I combination study of ...... e in adults with solid tumors.
@en
P2093
P50
P1476
A phase I combination study of ...... ne in adults with solid tumors
@en
P2093
Arun Rajan
Corey A Carter
Jiuping Ji
Martin Gutierrez
Mary Ann Yancey
Ronan J Kelly
Shawn Spencer
Shivaani Kummar
Sukyung Woo
William Douglas Figg
P304
P356
10.1158/1078-0432.CCR-11-2425
P407
P577
2012-02-27T00:00:00Z