Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
about
Ceramide generated by sphingomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cellsA house divided: ceramide, sphingosine, and sphingosine-1-phosphate in programmed cell deathRole of Bax in resveratrol-induced apoptosis of colorectal carcinoma cells.Plant sterols as anticancer nutrients: evidence for their role in breast cancerA review of ceramide analogs as potential anticancer agentsSphingolipids as cell fate regulators in lung development and diseaseBioactive lipids and the control of Bax pro-apoptotic activityAblation of dihydroceramide desaturase confers resistance to etoposide-induced apoptosis in vitroApoptosis induced by Ginkgo biloba (EGb761) in melanoma cells is Mcl-1-dependentRole of ceramide in diabetes mellitus: evidence and mechanisms.Ceramide mediates FasL-induced caspase 8 activation in colon carcinoma cells to enhance FasL-induced cytotoxicity by tumor-specific cytotoxic T lymphocytesMultigene analysis of Rb pathway and apoptosis control in esophageal squamous cell carcinoma identifies patients with good prognosis.Paclitaxel-induced apoptosis in BJAB cells proceeds via a death receptor-independent, caspases-3/-8-driven mitochondrial amplification loop.Combined p53/Bax mutation results in extremely poor prognosis in gastric carcinoma with low microsatellite instability.Mutation of p53 and consecutive selective drug resistance in B-CLL occurs as a consequence of prior DNA-damaging chemotherapy.Tumor necrosis factor alpha sensitizes malignant cells to chemotherapeutic drugs via the mitochondrial apoptosis pathway independently of caspase-8 and NF-kappaB.Arsenic trioxide triggers a regulated form of caspase-independent necrotic cell death via the mitochondrial death pathway.Bax-dependent regulation of Bak by voltage-dependent anion channel 2.Induction of p21CIP/WAF-1 and G2 arrest by ionizing irradiation impedes caspase-3-mediated apoptosis in human carcinoma cells.Genetic dissection of apoptosis and cell cycle control in response of colorectal cancer treated with preoperative radiochemotherapy.Bak functionally complements for loss of Bax during p14ARF-induced mitochondrial apoptosis in human cancer cells.Apoptosis and the activity of ceramide, Bax and Bcl-2 in the lungs of neonatal rats exposed to limited and prolonged hyperoxia.Mcl-1 determines the Bax dependency of Nbk/Bik-induced apoptosis.Endogenous Bak inhibitors Mcl-1 and Bcl-xL: differential impact on TRAIL resistance in Bax-deficient carcinoma.Ceramide glycosylation catalyzed by glucosylceramide synthase and cancer drug resistance.Synthetic glycosidated phospholipids induce apoptosis through activation of FADD, caspase-8 and the mitochondrial death pathway.Bcl2L13 is a ceramide synthase inhibitor in glioblastoma.Mitochondrially targeted ceramides preferentially promote autophagy, retard cell growth, and induce apoptosis.Inhibition of ceramide metabolism sensitizes human leukemia cells to inhibition of BCL2-like proteinsCancer treatment strategies targeting sphingolipid metabolism.New advances on structural and biological functions of ceramide in apoptotic/necrotic cell death and cancer.Ceramide: second messenger or modulator of membrane structure and dynamics?Rapamycin mimics the incompatibility reaction in the fungus Podospora anserina.New advances on prostate carcinogenesis and therapies: involvement of EGF-EGFR transduction system.SapC-DOPS nanovesicles induce Smac- and Bax-dependent apoptosis through mitochondrial activation in neuroblastomas.Apoptosis resistance, mitotic catastrophe, and loss of ploidy control in Burkitt lymphoma.In vitro and in vivo model systems used in prostate cancer research.Ceramide channels: destabilization by Bcl-xL and role in apoptosisMitochondrial ceramide and the induction of apoptosisVitamin C Induces Apoptosis in Human Colon Cancer Cell Line, HCT-8 Via the Modulation of Calcium Influx in Endoplasmic Reticulum and the Dissociation of Bad from 14-3-3β.
P2860
Q24646847-63917EF2-394E-44CF-8F79-896477458F18Q24675372-B58418DA-99B8-494A-944D-10FD5F592A3FQ24793084-01E24CDE-70DC-41DA-B88E-48EEE09309CCQ26861053-A5FEE8F6-BB78-46EF-9527-362DF8B11FE5Q27009351-FFA2631B-5FFB-4DA1-B83C-88FB78739FC0Q28084945-DB2D68DE-4310-43EA-89D0-AC41C129ABEFQ28240923-52FF425C-4D7E-49FC-9CFB-2EFB41FA8781Q28595077-3A445B12-D2C4-4D6C-AF58-7305E2AF354FQ28649832-09114D20-5AD7-4460-BBB6-2E5EAD283044Q30351934-8A2D2263-FFDB-40E1-B18F-079E6EFC0D5FQ30357159-C2183247-DDF5-438A-BFF4-059F8A7A1D6EQ33185435-76CDDFEF-49DE-4871-A2B9-B110DFA2C0CAQ33186742-F8500912-47BC-4C81-A879-8B6DB39FFF1EQ33186848-5EF0778E-B89B-452B-98A2-DDCD2E332454Q33186850-5443B297-D43C-49EB-88B2-E8B10D18EB73Q33205160-27D00BCC-CECE-40A7-A739-638BD452D1ACQ33211246-5E4DF93C-F239-4976-832D-24C5166ACC42Q33212700-DC90B5BA-A507-4BAB-9798-A52FFF2C8663Q33228616-7173CBDF-9AE1-4BE1-8C89-5512BBF0E668Q33242983-D37D32CB-7C40-44C5-A383-11D9F6808ED3Q33250477-B6E15AD4-71C4-45B5-B5C3-82BDA553F828Q33251853-5C543785-D479-47E1-B7BB-26AC6A08B1A1Q33306334-91D606FB-931D-4D5A-BD59-643BB299C227Q33544118-9BE3B90C-6406-46B4-B572-FEB74C31CD48Q33733991-5069DBC3-B705-4B3C-AF54-B0A1F0B39AE5Q33855963-8A25DD4B-7B92-474C-BD74-71E456A6C0E3Q34413943-554CCD38-5FF6-42ED-8D42-DCF0087B474CQ34503377-ED079E04-6F26-44CA-8D8E-B7148F3F9CBFQ34559507-EF9D7856-C7A2-41FA-BECB-AF7FE46AF313Q34790629-840FF05C-165E-4D59-8A54-2030F254DAEBQ34975049-17F5BBF9-A349-4E95-B1A9-D5A91EDF06D7Q34984863-2C125EE3-91A3-46A9-A227-FA5107706E01Q34993649-2074A14E-963A-4C10-B6FB-5EE25A10F9AAQ35149046-A5B50775-82A1-405B-91A7-DB177238AD6BQ35425036-5D4A44A5-B559-4C3C-B4C3-14A064352495Q35535592-73444532-9DA1-4B96-91B5-700779FEF734Q35806390-6103485E-FBF9-4A94-A100-32FC12BB10CBQ36011641-FF00270E-5D13-4A16-9276-5D57B3F47065Q36259131-0A89C630-ED54-48E1-872A-2FCF998AF4D3Q36431015-3CA87E37-BABB-4833-AB98-D59C8B5CF00B
P2860
Ceramide induces mitochondrial activation and apoptosis via a Bax-dependent pathway in human carcinoma cells.
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@ast
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@en
type
label
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@ast
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@en
prefLabel
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@ast
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@en
P2093
P2860
P356
P1433
P1476
Ceramide induces mitochondrial ...... hway in human carcinoma cells.
@en
P2093
Bernd Dörken
Bernd Gillissen
Lilian Stärck
Peter T Daniel
Thomas Wieder
Vilma Graupner
P2860
P2888
P304
P356
10.1038/SJ.ONC.1205497
P407
P577
2002-06-01T00:00:00Z
P5875
P6179
1010199811