Generation and functional characterization of intracellular antibodies interacting with the kinase domain of human EGF receptor.
about
Directed evolution of single-chain Fv for cytoplasmic expression using the beta-galactosidase complementation assay results in proteins highly susceptible to protease degradation and aggregationSpecific in vivo knockdown of protein function by intrabodiesSelection of antibodies that regulate phenotype from intracellular combinatorial antibody libraries.An evolved Mxe GyrA intein for enhanced production of fusion proteinsNovel antibodies as anticancer agents.State of the art in tumor antigen and biomarker discovery.Facile chemical functionalization of proteins through intein-linked yeast displayIntracellular antibodies and cancer: new technologies offer therapeutic opportunities.Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering.A bispecific transmembrane antibody simultaneously targeting intra- and extracellular epitopes of the epidermal growth factor receptor inhibits receptor activation and tumor cell growth.In vivo expression and binding activity of scFv-RWAV, which recognizes the coat protein of tomato leaf curl New Delhi virus (family Geminiviridae).Directing evolution: the next revolution in drug discovery?
P2860
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P2860
Generation and functional characterization of intracellular antibodies interacting with the kinase domain of human EGF receptor.
description
2003 nî lūn-bûn
@nan
2003 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի մարտին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
Generation and functional char ...... domain of human EGF receptor.
@ast
Generation and functional char ...... domain of human EGF receptor.
@en
type
label
Generation and functional char ...... domain of human EGF receptor.
@ast
Generation and functional char ...... domain of human EGF receptor.
@en
prefLabel
Generation and functional char ...... domain of human EGF receptor.
@ast
Generation and functional char ...... domain of human EGF receptor.
@en
P2093
P2860
P356
P1433
P1476
Generation and functional char ...... domain of human EGF receptor.
@en
P2093
Carlos F Barbas
Nancy E Hynes
Roger R Beerli
Stephen Hyland
Winfried Wels
P2860
P2888
P304
P356
10.1038/SJ.ONC.1206299
P407
P577
2003-03-01T00:00:00Z
P5875
P6179
1027274663