Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
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Bradykinin induces translocation of the protein kinase C isoforms alpha, epsilon, and zetaBradykinin-induced activation of nociceptors: receptor and mechanistic studies on the neonatal rat spinal cord-tail preparation in vitroFunctional bradykinin B1 receptors are expressed in nociceptive neurones and are upregulated by the neurotrophin GDNFIcatibant: HOE 140, JE 049, JE049Bradyzide, a potent non-peptide B(2) bradykinin receptor antagonist with long-lasting oral activity in animal models of inflammatory hyperalgesiaIn various tumour cell lines the peptide bradykinin B(2) receptor antagonist, Hoe 140 (Icatibant), may act as mitogenic agonistBradykinin increases Na(+)-K(+) pump activity in cultured guinea-pig tracheal smooth muscle cellsInhibition of bradykinin-induced vasodilation in human forearm vasculature by icatibant, a potent B2-receptor antagonist.The nonpeptide B2 receptor antagonist FR173657: inhibition of effects of bradykinin related to its role in nociceptionThe nonpeptide WIN 64338 is a bradykinin B2 receptor antagonistMediation by prostaglandins of the nitric oxide-induced neurogenic vasodilatation in rat skinExpression and function of bradykinin B1 and B2 receptors in normal and inflamed rat urinary bladder urotheliumUp-regulation of kinin B1 receptor in the lung of streptozotocin-diabetic rat: autoradiographic and functional evidenceCollaboration for rare disease drug discovery researchHoe 140 a new potent and long acting bradykinin-antagonist: in vivo studiesCharacterization of the bradykinin receptor in the human nasal airway using the binding of [125I]-Hoe 140Reduction by Hoe 140, the B2 kinin receptor antagonist, of antigen-induced nasal blockage.Synthesis and analysis of potent, more lipophilic derivatives of the bradykinin B2 receptor antagonist peptide Hoe 140.Use of fluorescence polarization detection for the measurement of fluopeptidetm binding to G protein-coupled receptors.Potential strategies for increasing drug-discovery productivity.Differential regulation of inducible and endothelial nitric oxide synthase by kinin B1 and B2 receptorsPrologue: kinins and related systems. New life for old discoveries.Identification of receptor ligands and receptor subtypes using antagonists in a capillary electrophoresis single-cell biosensor separation system.HAE therapies: past present and future.Bradykinin receptors in mouse and rat isolated superior cervical gangliaThe sixth transmembrane domains of the human B1 and B2 bradykinin receptors are structurally compatible and involved in discriminating between subtype-selective agonists.Role of kinins in anaphylactic-induced bronchoconstriction mediated by tachykinins in guinea-pigs.Bradykinin B2 receptors and coupling mechanisms in the smooth muscle of the guinea-pig taenia caeciPharmacological characterization of bradykinin receptors in canine cultured tracheal smooth muscle cells.Involvement of B2 receptors in the bradykinin-induced relaxation of guinea-pig isolated trachea.Characterization of kinin receptors modulating neurogenic contractions of the mouse isolated vas deferensRole of bradykinin in the hyperaemia following acid challenge of the rat gastric mucosaDisplay of the characteristics of endothelium-derived hyperpolarizing factor by a cytochrome P450-derived arachidonic acid metabolite in the coronary microcirculation.The identification of an orally active, nonpeptide bradykinin B2 receptor antagonist, FR173657Effects of FR173657, a non-peptide B2 antagonist, on kinin-induced hypotension, visceral and peripheral oedema formation and bronchoconstrictionEffects of the non-peptide B2 antagonist FR173657 on kinin-induced smooth muscle contraction and relaxation, vasoconstriction and prostaglandin release.Effects of trout bradykinin on the motility of the trout stomach and intestine: evidence for a receptor distinct from mammalian B1 and B2 subtypesEffects of a nonpeptide bradykinin B2 receptor antagonist, FR167344, on different in vivo animal models of inflammationInvolvement of bradykinin B1 and B2 receptors in relaxation of mouse isolated trachea.Effect of chronic bradykinin B2 receptor blockade on blood pressure of conscious Dahl salt-resistant rats
P2860
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P2860
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
description
1991 nî lūn-bûn
@nan
1991 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի մարտին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@ast
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@en
type
label
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@ast
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@en
prefLabel
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@ast
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@en
P2093
P2860
P1476
Hoe 140 a new potent and long acting bradykinin-antagonist: in vitro studies.
@en
P2093
Breipohl G
Gerhards HJ
P2860
P304
P356
10.1111/J.1476-5381.1991.TB12248.X
P407
P577
1991-03-01T00:00:00Z