Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
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An update on the role of intestinal cytochrome P450 enzymes in drug dispositionProfile of territrem metabolism and cytochrome P-450 3A expression in liver microsomes from Wistar rats of both genders as a function of ageSucralose, a synthetic organochlorine sweetener: overview of biological issuesTriptolide Induces hepatotoxicity via inhibition of CYP450s in Rat liver microsomes.Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humans.Advanced pharmacokinetic models based on organ clearance, circulatory, and fractal concepts.CRISPR knockout rat cytochrome P450 3A1/2 model for advancing drug metabolism and pharmacokinetics research.In vitro and in vivo small intestinal metabolism of CYP3A and UGT substrates in preclinical animals species and humans: species differences.Endotoxin-Mediated Downregulation of Hepatic Drug Transporters in HIV-1 Transgenic Rats.Pharmacokinetics of mirtazapine and its main metabolites after single intravenous and oral administrations in rats at two dose rates.Cytochrome P450 epoxygenase dependence of opioid analgesia: fluconazole does not interfere with remifentanil-mediated analgesia in human subjects.Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam.Effect of ursodeoxycholic acid on the pharmacokinetics of midazolam and CYP3A in the liver and intestine of rats.In vitro and in vivo characterization of CYP inhibition by 1-aminobenzotriazole in rats.Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy.The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine.Species differences in hepatic and intestinal metabolic activities for 43 human cytochrome P450 substrates between humans and rats or dogs.Sex differences in pharmacokinetics of cilostazol in rats.
P2860
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P2860
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@ast
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@en
type
label
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@ast
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@en
prefLabel
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@ast
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@en
P2093
P356
P1476
Isolation and characterization of a new major intestinal CYP3A form, CYP3A62, in the rat.
@en
P2093
P304
P356
10.1124/JPET.103.061671
P407
P577
2004-03-05T00:00:00Z