A resource for large-scale RNA-interference-based screens in mammals.
about
Selective gene silencing by viral delivery of short hairpin RNAThe F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenanceA genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stabilityParkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint controlEST-based genome-wide gene inactivation identifies ARAP3 as a host protein affecting cellular susceptibility to anthrax toxinGenome-wide RNA-mediated interference screen identifies miR-19 targets in Notch-induced T-cell acute lymphoblastic leukaemiaThe Trithorax group protein Ash2l and Saf-A are recruited to the inactive X chromosome at the onset of stable X inactivationIdentifying druggable disease-modifying gene productsRNA interference is ineffective as a routine method for gene silencing in chick embryos as monitored by fgf8 silencingChemical genomics in yeastA reverse genetic screen in Drosophila using a deletion-inducing mutagenGeneSeer: a sage for gene names and genomic resources.High-throughput isolation of ultra-pure plasmid DNA by a robotic system.RNAi Codex: a portal/database for short-hairpin RNA (shRNA) gene-silencing constructsA new age in functional genomics using CRISPR/Cas9 in arrayed library screeningNeuroanatomy goes viral!Synthetic lethal screens as a means to understand and treat MYC-driven cancersProliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovariesStructure of C3PO and mechanism of human RISC activationSynthetic lethality in lung cancer and translation to clinical therapiesTTP and BRF proteins nucleate processing body formation to silence mRNAs with AU-rich elementsRNA interference and potential therapeutic applications of short interfering RNAsA novel EST-derived RNAi screen reveals a critical role for farnesyl diphosphate synthase in β2-adrenergic receptor internalization and down-regulationInsertional mutagenesis in mice: new perspectives and toolsRAS Synthetic Lethal Screens Revisited: Still Seeking the Elusive Prize?Second-generation shRNA libraries covering the mouse and human genomesp27Kip1 knockdown induces proliferation in the organ of Corti in culture after efficient shRNA lentiviral transductionCyclin-dependent kinase-associated proteins Cks1 and Cks2 are essential during early embryogenesis and for cell cycle progression in somatic cellsKLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancerScreenBEAM: a novel meta-analysis algorithm for functional genomics screens via Bayesian hierarchical modelingGenome-scale CRISPR-Cas9 knockout screening in human cellsA CRISPR toolbox to study virus-host interactionsOrganic small hairpin RNAs (OshR): a do-it-yourself platform for transgene-based gene silencing.Targeted comparative RNA interference analysis reveals differential requirement of genes essential for cell proliferationPrioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategyA functional genome-wide RNAi screen identifies TAF1 as a regulator for apoptosis in response to genotoxic stress.A streamlined sub-cloning procedure to transfer shRNA from a pSM2 vector to a pGIPZ lentiviral vector.Lightweight genome viewer: portable software for browsing genomics data in its chromosomal context.Genome-wide screening for gene function using RNAi in mammalian cells.
P2860
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P2860
A resource for large-scale RNA-interference-based screens in mammals.
description
2004 nî lūn-bûn
@nan
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A resource for large-scale RNA-interference-based screens in mammals.
@ast
A resource for large-scale RNA-interference-based screens in mammals.
@en
type
label
A resource for large-scale RNA-interference-based screens in mammals.
@ast
A resource for large-scale RNA-interference-based screens in mammals.
@en
prefLabel
A resource for large-scale RNA-interference-based screens in mammals.
@ast
A resource for large-scale RNA-interference-based screens in mammals.
@en
P2093
P50
P356
P1433
P1476
A resource for large-scale RNA-interference-based screens in mammals
@en
P2093
Andy O'Shaughnessy
Jose M Silva
Kenneth Chang
Kim Scobie
Lidia Gnoj
Michele Cleary
Mike Schlabach
Patrick J Paddison
Ravi Sachidanandam
P2888
P304
P356
10.1038/NATURE02370
P407
P577
2004-03-01T00:00:00Z
P6179
1018499830