Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle
about
Ribosomal protein S6 is a selective mediator of TRAIL-apoptotic signalingExome sequencing identifies autosomal-dominant SRP72 mutations associated with familial aplasia and myelodysplasiaDig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell linesSensitive and selective plasmon ruler nanosensors for monitoring the apoptotic drug response in leukemia.High-throughput RNAi screening in vitro: from cell lines to primary cells.A TRAIL receptor-dependent synthetic lethal relationship between MYC activation and GSK3beta/FBW7 loss of functionGroup VIA phospholipase A2 mitigates palmitate-induced β-cell mitochondrial injury and apoptosisResidues in SRP9/14 essential for elongation arrest activity of the signal recognition particle define a positively charged functional domain on one side of the protein.Defining the specificity of cotranslationally acting chaperones by systematic analysis of mRNAs associated with ribosome-nascent chain complexes.Sulforaphane induces apoptosis in rhabdomyosarcoma and restores TRAIL-sensitivity in the aggressive alveolar subtype leading to tumor elimination in mice.ROS and CHOP are critical for dibenzylideneacetone to sensitize tumor cells to TRAIL through induction of death receptors and downregulation of cell survival proteins.Hierarchical regulation of mRNA partitioning between the cytoplasm and the endoplasmic reticulum of mammalian cellsDiversity and selectivity in mRNA translation on the endoplasmic reticulumRegulation in the targeting of TRAIL receptor 1 to cell surface via GODZ for TRAIL sensitivity in tumor cellsDown-regulation of the trypanosomatid signal recognition particle affects the biogenesis of polytopic membrane proteins but not of signal peptide-containing proteins.Signal sequence- and translation-independent mRNA localization to the endoplasmic reticulumImplication of the SMN complex in the biogenesis and steady state level of the signal recognition particle.The plant defensin NaD1 induces tumor cell death via a non-apoptotic, membranolytic process.Tumor Necrosis Factor-related apoptosis-inducing ligand (TRAIL) Receptor-1 and Receptor-2 agonists for cancer therapy.A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells.Breast cancer proteome takes more than two to tango on TRAIL: beat them at their own game.Molecular insights into intracellular RNA localization.All roads lead to Rome (but some may be harder to travel): SRP-independent translocation into the endoplasmic reticulum.Localization of mRNAs to the endoplasmic reticulum.FLLL12 induces apoptosis in lung cancer cells through a p53/p73-independent but death receptor 5-dependent pathwayIntracellular localization of DR5 and related regulatory pathways as a mechanism of resistance to TRAIL in cancer.Design and synthesis of pyrrolidine-containing sphingomimetics.Inhibition of NF-kappaB signaling by quinacrine is cytotoxic to human colon carcinoma cell lines and is synergistic in combination with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) or oxaliplatinIRF-5 is a mediator of the death receptor-induced apoptotic signaling pathway.Depletion of signal recognition particle 72kDa increases radiosensitivity.TRAIL and vitamins: opting for keys to castle of cancer proteome instead of open sesame.Analyzing mRNA localization to the endoplasmic reticulum via cell fractionation.Free fatty acids sensitise hepatocytes to TRAIL mediated cytotoxicitySilencing the epigenetic silencer KDM4A for TRAIL and DR5 simultaneous induction and antitumor therapy.Camalexin induces apoptosis in T-leukemia Jurkat cells by increased concentration of reactive oxygen species and activation of caspase-8 and caspase-9.Mechanisms of enhancement of TRAIL tumoricidal activity against human cancer cells of different origin by dipyridamole.Death Receptors: New Opportunities in Cancer Therapy.Determination of the Relative Potency of an Anti-TNF Monoclonal Antibody (mAb) by Neutralizing TNF Using an In Vitro Bioanalytical Method.Mutations in signal recognition particle SRP54 cause syndromic neutropenia with Shwachman-Diamond-like features.Combined application of Embelin and tumor necrosis factor-related apoptosis-inducing ligand inhibits proliferation and invasion in osteosarcoma cells via caspase-induced apoptosis.
P2860
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P2860
Differential regulation of the TRAIL death receptors DR4 and DR5 by the signal recognition particle
description
2004 nî lūn-bûn
@nan
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Differential regulation of the ...... he signal recognition particle
@ast
Differential regulation of the ...... he signal recognition particle
@en
type
label
Differential regulation of the ...... he signal recognition particle
@ast
Differential regulation of the ...... he signal recognition particle
@en
prefLabel
Differential regulation of the ...... he signal recognition particle
@ast
Differential regulation of the ...... he signal recognition particle
@en
P2093
P2860
P356
P1476
Differential regulation of the ...... he signal recognition particle
@en
P2093
Deborah A Knee
Klaus W Wagner
Marc Nasoff
Pedro Aza-Blanc
Quinn L Deveraux
Yan-Guo Ren
P2860
P304
P356
10.1091/MBC.E04-03-0184
P577
2004-09-08T00:00:00Z