Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.
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The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infectionModulation of cellular Hsp72 levels in undifferentiated and neuron-like SH-SY5Y cells determines resistance to staurosporine-induced apoptosisFacilitating Akt clearance via manipulation of Hsp70 activity and levels.Hyperthermia as an immunotherapy strategy for cancerAkt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells.Expression profile of heat shock response factors during hookworm larval activation and parasitic development.Inhibiting induction of heat shock proteins as a strategy to enhance cancer therapy.HSF1: Guardian of Proteostasis in CancerInvolvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin.Inducible hsp70 in the regulation of cancer cell survival: analysis of chaperone induction, expression and activityHSP90 inhibitors in the context of heat shock and the unfolded protein response: effects on a primary canine pulmonary adenocarcinoma cell line.Hyperthermia adds to trabectedin effectiveness and thermal enhancement is associated with BRCA2 degradation and impairment of DNA homologous recombination repair.Human neuroblastoma SH-SY5Y cells show increased resistance to hyperthermic stress after differentiation, associated with elevated levels of Hsp72.KNK437, a benzylidene lactam compound, sensitises prostate cancer cells to the apoptotic effect of hyperthermia.Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cellsDevelopment of thermotolerance requires interaction between polymerase-beta and heat shock proteins.Effects of KNK437 on heat-induced methylation of histone H3 in human oral squamous cell carcinoma cells.Induction of radiation resistance by a heat shock protein inhibitor, KNK437, in human glioblastoma cells.Attenuation of chronic thermotolerance by KNK437, a benzylidene lactam compound, enhances thermal radiosensitization in mild temperature hyperthermia combined with low dose-rate irradiation.Targeting Heat Shock Proteins in Cancer: A Promising Therapeutic ApproachNuclear heat shock protein 110 expression is associated with poor prognosis and hyperthermo-chemotherapy resistance in gastric cancer patients with peritoneal metastasis.
P2860
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P2860
Effects of a heat shock protein inhibitor KNK437 on heat sensitivity and heat tolerance in human squamous cell carcinoma cell lines differing in p53 status.
description
2004 nî lūn-bûn
@nan
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Effects of a heat shock protei ...... lines differing in p53 status.
@ast
Effects of a heat shock protei ...... lines differing in p53 status.
@en
type
label
Effects of a heat shock protei ...... lines differing in p53 status.
@ast
Effects of a heat shock protei ...... lines differing in p53 status.
@en
prefLabel
Effects of a heat shock protei ...... lines differing in p53 status.
@ast
Effects of a heat shock protei ...... lines differing in p53 status.
@en
P2093
P2860
P1476
Effects of a heat shock protei ...... lines differing in p53 status.
@en
P2093
P2860
P304
P356
10.1080/09553000412331283470
P577
2004-08-01T00:00:00Z