Antitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2).
about
Applications and Challenges for Use of Cell-Penetrating Peptides as Delivery Vectors for Peptide and Protein CargosOptimizing CIGB-300 intralesional delivery in locally advanced cervical cancer.Conservation, variability and the modeling of active protein kinasesSafety and preliminary efficacy data of a novel casein kinase 2 (CK2) peptide inhibitor administered intralesionally at four dose levels in patients with cervical malignancies.Maurocalcine as a non toxic drug carrier overcomes doxorubicin resistance in the cancer cell line MDA-MB 231Protein kinases CK1 and CK2 as new targets for neurodegenerative diseases.Synergistic interactions of the anti-casein kinase 2 CIGB-300 peptide and chemotherapeutic agents in lung and cervical preclinical cancer models.Identification of a Potent Allosteric Inhibitor of Human Protein Kinase CK2 by Bacterial Surface Display Library Screening.Protein kinase CK2--a key suppressor of apoptosis.Identification of Vimentin as a Potential Therapeutic Target against HIV InfectionCK2-NCoR signaling cascade promotes prostate tumorigenesisThe Use of Phage-Displayed Peptide Libraries to Develop Tumor-Targeting Drugs.Systemic administration of antisense oligonucleotides simultaneously targeting CK2α and α' subunits reduces orthotopic xenograft prostate tumors in mice.Protein kinase CK2 inhibitors: a patent review.Casein kinase: the triple meaning of a misnomer.Targeting chronic lymphocytic leukemia using CIGB-300, a clinical-stage CK2-specific cell-permeable peptide inhibitor.Casein kinases as potential therapeutic targets.The synthetic peptide CIGB-300 modulates CK2-dependent signaling pathways affecting the survival and chemoresistance of non-small cell lung cancer cell linesPharmacologic inhibition of the CK2-mediated phosphorylation of B23/NPM in cancer cells selectively modulates genes related to protein synthesis, energetic metabolism, and ribosomal biogenesis.Building Cell Selectivity into CPP-Mediated Strategies.Human antibodies reactive to NeuGcGM3 ganglioside have cytotoxic antitumor properties.Sensitivity of tumor cells towards CIGB-300 anticancer peptide relies on its nucleolar localization.CIGB-300, a synthetic peptide-based drug that targets the CK2 phosphoaceptor domain. Translational and clinical research.Mass Spectrometry Reveals Protein Kinase CK2 High-Order Oligomerization via the Circular and Linear Assembly.Shortened Penetratin Cell-Penetrating Peptide Is Insufficient for Cytosolic Delivery of a Grb7 Targeting Peptide.Therapeutic targeting of CK2 in acute and chronic leukemias.
P2860
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P2860
Antitumor effect of a novel proapoptotic peptide that impairs the phosphorylation by the protein kinase 2 (casein kinase 2).
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Antitumor effect of a novel pr ...... in kinase 2 (casein kinase 2).
@ast
Antitumor effect of a novel pr ...... in kinase 2 (casein kinase 2).
@en
type
label
Antitumor effect of a novel pr ...... in kinase 2 (casein kinase 2).
@ast
Antitumor effect of a novel pr ...... in kinase 2 (casein kinase 2).
@en
prefLabel
Antitumor effect of a novel pr ...... in kinase 2 (casein kinase 2).
@ast
Antitumor effect of a novel pr ...... in kinase 2 (casein kinase 2).
@en
P2093
P1433
P1476
Antitumor effect of a novel pr ...... ein kinase 2 (casein kinase 2)
@en
P2093
Alicia Santos
Boris Acevedo
Ernesto López
Isis Torrens
Nelson S Vispo
Osmani Mendoza
Osvaldo Reyes
Ricardo Silva
Silvio E Perea
Yaquelin Puchades
P304
P356
10.1158/0008-5472.CAN-04-2086
P407
P577
2004-10-01T00:00:00Z