Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.
about
The DNA helicase-primase complex as a target for herpes viral infectionA viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responsesChk2 is required for HSV-1 ICP0-mediated G2/M arrest and enhancement of virus growthHerpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection.Homologous recombinational repair factors are recruited and loaded onto the viral DNA genome in Epstein-Barr virus replication compartments.Inhibition of herpes simplex virus type 1 replication by adeno-associated virus rep proteins depends on their combined DNA-binding and ATPase/helicase activities.ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response.Evidence that herpes simplex virus DNA derived from quiescently infected cells in vitro, and latently infected cells in vivo, is physically damagedAdeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection.Live covisualization of competing adeno-associated virus and herpes simplex virus type 1 DNA replication: molecular mechanisms of interaction.Interactions between DNA viruses, ND10 and the DNA damage response.H2AX phosphorylation and DNA damage kinase activity are dispensable for herpes simplex virus replication.Herpes simplex virus 1 DNA is in unstable nucleosomes throughout the lytic infection cycle, and the instability of the nucleosomes is independent of DNA replication.Linker histones are mobilized during infection with herpes simplex virus type 1.
P2860
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P2860
Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
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2005年学术文章
@wuu
2005年学术文章
@zh-cn
2005年学术文章
@zh-hans
2005年学术文章
@zh-my
2005年学术文章
@zh-sg
2005年學術文章
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name
Inhibition of the herpes simpl ...... f DNA damage during infection.
@ast
Inhibition of the herpes simpl ...... f DNA damage during infection.
@en
type
label
Inhibition of the herpes simpl ...... f DNA damage during infection.
@ast
Inhibition of the herpes simpl ...... f DNA damage during infection.
@en
prefLabel
Inhibition of the herpes simpl ...... f DNA damage during infection.
@ast
Inhibition of the herpes simpl ...... f DNA damage during infection.
@en
P2860
P1433
P1476
Inhibition of the herpes simpl ...... of DNA damage during infection
@en
P2093
Dianna E Wilkinson
P2860
P304
P356
10.1128/JVI.79.11.7162-7171.2005
P577
2005-06-01T00:00:00Z