SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity.
about
Matricellular proteins: a sticky affair with cancersMatrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasionSPARC Promotes Cell Invasion In Vivo by Decreasing Type IV Collagen Levels in the Basement MembraneForce-induced unfolding of fibronectin in the extracellular matrix of living cellsGene expression analysis of zebrafish heart regenerationProteins involved in platelet signaling are differentially regulated in acute coronary syndrome: a proteomic studyAn unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.miR-8 modulates cytoskeletal regulators to influence cell survival and epithelial organization in Drosophila wings.Cigarette smoke alters the secretome of lung epithelial cells.Integrated analysis of global mRNA and protein expression data in HEK293 cells overexpressing PRL-1.Display technologies: application for the discovery of drug and gene delivery agents.IFATS collection: Combinatorial peptides identify alpha5beta1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells.Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4Integrins as Therapeutic Targets for Respiratory DiseasesMatricellular proteins in the trabecular meshwork: review and update.TGF-β2-mediated ocular hypertension is attenuated in SPARC-null mice.Osteonectin/SPARC polymorphisms in Caucasian men with idiopathic osteoporosisMatricellular proteins and biomaterials.PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.Inhibition of hyaluronan synthesis reduces versican and fibronectin levels in trabecular meshwork cells.Nitric oxide-induced vasorelaxation in response to PnTx2-6 toxin from Phoneutria nigriventer spider in rat cavernosal tissue.Transcriptome analysis of the desert locust central nervous system: production and annotation of a Schistocerca gregaria EST databaseSPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGFThe effects of age and the expression of SPARC on extracellular matrix production by cardiac fibroblasts in 3-D culturesRevisiting the matricellular concept.SPARC promotes pericyte recruitment via inhibition of endoglin-dependent TGF-β1 activity.Deletion of the SPARC acidic domain or EGF-like module reduces SPARC-induced migration and signaling through p38 MAPK/HSP27 in glioma.Secreted protein acidic and rich in cysteine (SPARC) inhibits integrin-mediated adhesion and growth factor-dependent survival signaling in ovarian cancer.Lenalidomide inhibits the malignant clone and up-regulates the SPARC gene mapping to the commonly deleted region in 5q- syndrome patients.Integrin β4 regulates SPARC protein to promote invasion.Phage-based molecular probes that discriminate force-induced structural states of fibronectin in vivoSecreted Protein Acidic and Rich in Cysteine in Ocular TissueSPARC Regulates Transforming Growth Factor Beta Induced (TGFBI) Extracellular Matrix Deposition and Paclitaxel Response in Ovarian Cancer Cells.Integrin α3β1 Binding to Fibronectin Is Dependent on the Ninth Type III Repeat.The SPARC-related factor SMOC-2 promotes growth factor-induced cyclin D1 expression and DNA synthesis via integrin-linked kinase.PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in gliomaMapping of SPARC/BM-40/osteonectin-binding sites on fibrillar collagens.Is SPARC an evolutionarily conserved collagen chaperone?Extracting a low-dimensional description of multiple gene expression datasets reveals a potential driver for tumor-associated stroma in ovarian cancer.
P2860
Q21296660-370AEE05-1FD3-4C18-91A2-124474A35319Q26824518-A07AC436-B82B-47FB-AB8B-4288016FADC3Q27309073-FE19258E-F070-4E21-8593-3B7C2DA1BD3DQ27334068-D1C24E4B-E866-4760-98F7-587DE3F06FC0Q28469029-6621B01E-13D4-4B47-AE68-BF5AB1652959Q28475779-CE9393E0-E8E2-4942-B9D7-BC2DA1019192Q30157382-C3A5DE8C-6CCE-4F12-A271-C8FBBE174133Q30359720-62F88BB8-0449-424A-84CA-62B97874F0A8Q30395716-3A6B3F1F-E0F6-4206-8117-907587C5B091Q30665898-1BC1625E-25CC-4B41-8858-319E49B071DAQ33264491-A674500B-8782-4ABD-9BC8-F0B3BB3887A8Q33347082-A60D4257-B0C4-4AB6-8F9E-FE2F750657BFQ33648561-5B9348C4-0EAF-4AD6-AD2A-064CB571E82AQ33668635-3C4C59A6-F630-450E-AC09-7B7DEEA99C85Q33820048-C1A2FD55-DFAF-4B80-AFAE-0301F8E3D1BBQ33835663-D277A3BA-C1A7-4075-BF6A-8A581171525FQ33923111-D1A9173E-9809-44CB-933B-0FD04F66581CQ34040283-BFCD1E4A-467B-402D-97D0-90D4773E229EQ34133079-1657B288-02DA-4A08-A165-11A5C7F1B141Q34431043-57D6DBD7-FC49-41FA-A374-17AEA1CD830EQ34471999-655D759C-BFDB-4563-B7CE-A5EEA67231FBQ34622646-F6EAD9A3-420C-45B5-969A-68C5613973CFQ34703983-32FC93E1-2182-4B21-BCEF-1E1D80445A9DQ34979996-EB06CF0B-366E-42DD-B615-C6FC589F415FQ35040298-A3403348-08DF-4C2F-B309-F593CE2A75B3Q35233858-1FE9C247-9FA8-45ED-91F0-13E1F53111AFQ35550776-740AFD08-22EC-4D7E-B0D4-C2DA9B252C67Q35730628-887A19B1-732B-4FAD-BD7C-A4338B573A7CQ35781408-92CE07A4-70AB-4330-99C4-69752C9AE6C4Q35844148-1BBE3F50-8805-4DBB-AEDA-98A7D6008A76Q35880044-20C30C45-B6C7-4902-ADA7-CA964C692726Q35983068-EC6C360B-929D-402D-A773-63D91636785FQ36074007-3EC8399F-0E39-459B-A6CB-96C943537D08Q36131297-958BA71A-4E45-41AD-A3C6-7D6F1F8B2203Q36283351-08B0D756-AEFA-435C-8FB7-7B1EB58EF65EQ36325966-5BA5319F-0D00-448C-973A-B634B21106C7Q36713508-673D4AA8-FC5A-4CBA-829C-4A9F6FCB74FCQ36744234-EECB4823-367C-49CF-8DF2-D9BCE1926D1AQ36769633-3E3C2DC2-4BA4-4AAF-A88E-F3B178908521Q36994579-A7CE64AE-A1A3-406A-BA7B-F9F09B3AF858
P2860
SPARC regulates extracellular matrix organization through its modulation of integrin-linked kinase activity.
description
2005 nî lūn-bûn
@nan
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@ast
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@en
type
label
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@ast
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@en
prefLabel
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@ast
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@en
P2093
P2860
P356
P1476
SPARC regulates extracellular ...... tegrin-linked kinase activity.
@en
P2093
E Helene Sage
Gail A Workman
Gretchen Baneyx
Marina Cardó-Vila
Matt Weaver
Priya M Menon
Sandra A Rempel
Shoukat Dedhar
Thomas H Barker
Wadih Arap
P2860
P304
36483-36493
P356
10.1074/JBC.M504663200
P407
P577
2005-08-22T00:00:00Z