NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
about
Upregulation of casein kinase 1epsilon in dorsal root ganglia and spinal cord after mouse spinal nerve injury contributes to neuropathic pain.Effect of intraperitoneal administered ginseng total saponins on hyperalgesia induced by repeated intramuscular injection of acidic saline in ratsSynaptic GluN2A and GluN2B containing NMDA receptors within the superficial dorsal horn activated following primary afferent stimulation.Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats.The use of ketamine in complex regional pain syndrome: possible mechanisms.Spatiotemporal pattern of concurrent spinal and supraspinal NF-κB expression after peripheral nerve injury.The use of subdissociative-dose ketamine for acute pain in the emergency department.Involvement of spinal NR2B-containing NMDA receptors in oxaliplatin-induced mechanical allodynia in rats.Peripheral nerve injury alters the expression of NF-κB in the rat's hippocampusAntihyperalgesic and analgesic properties of the N-methyl-D-aspartate (NMDA) receptor antagonist neramexane in a human surrogate model of neurogenic hyperalgesia.Intracisternal administration of NR2 subunit antagonists attenuates the nociceptive behavior and p-p38 MAPK expression produced by compression of the trigeminal nerve root.Liposome reconstitution and modulation of recombinant N-methyl-D-aspartate receptor channels by membrane stretch.Isoflurane/nitrous oxide anesthesia induces increases in NMDA receptor subunit NR2B protein expression in the aged rat brainDose escalating safety study of CNS 5161 HCl, a new neuronal glutamate receptor antagonist (NMDA) for the treatment of neuropathic painNitrous oxide persistently alleviates pain hypersensitivity in neuropathic rats: A dose-dependent effectInteraction between ephrins/Eph receptors and excitatory amino acid receptors: possible relevance in the regulation of synaptic plasticity and in the pathophysiology of neuronal degeneration.Emerging drugs in neuropathic pain.Low dose ketamine: a therapeutic and research tool to explore N-methyl-D-aspartate (NMDA) receptor-mediated plasticity in pain pathways.Opposing action of conantokin-G on synaptically and extrasynaptically-activated NMDA receptors.Targeting the NMDA receptor subunit NR2B for the treatment of neuropathic painSelective vulnerability of hippocampal cornu ammonis 1 pyramidal cells to excitotoxic insult is associated with the expression of polyamine-sensitive N-methyl-D-asparate-type glutamate receptors.Current approaches with the glutamatergic system as targets in the treatment of neuropathic pain.Role of spinal neurotransmitter receptors in itch: new insights into therapies and drug development.Ion channel blockers for the treatment of neuropathic pain.Efficacy of outpatient ketamine infusions in refractory chronic pain syndromes: a 5-year retrospective analysis.Pharmacokinetic and pharmacodynamic considerations for NMDA receptor antagonists in the treatment of chronic neuropathic pain.Ketamine in pain management.Neuronal calcium signaling in chronic pain.Expert opinion on emerging drugs: chronic low back pain.Prolonged ketamine infusion as a therapy for complex regional pain syndrome: synergism with antagonism?Reduction of anion reversal potential subverts the inhibitory control of firing rate in spinal lamina I neurons: towards a biophysical basis for neuropathic pain.Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents.Glutamate transporters prevent excessive activation of NMDA receptors and extrasynaptic glutamate spillover in the spinal dorsal horn.Effects of low-dose intranasal (S)-ketamine in patients with neuropathic pain.Therapies and mechanisms of opioid withdrawal.Depletion of capsaicin-sensitive afferents prevents lamina-dependent increases in spinal N-methyl-D-aspartate receptor subunit 1 expression and phosphorylation associated with thermal hyperalgesia in neuropathic rats.St John's wort greatly decreases the plasma concentrations of oral S-ketamine.Activation of spinal NF-κB/p65 contributes to peripheral inflammation and hyperalgesia in rat adjuvant-induced arthritis.
P2860
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P2860
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@ast
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@en
type
label
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@ast
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@en
prefLabel
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@ast
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@en
P356
P1476
NMDA antagonists and neuropathic pain--multiple drug targets and multiple uses.
@en
P2093
P304
P356
10.2174/1381612054865082
P577
2005-01-01T00:00:00Z