Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains.
about
Proteoglycan form and function: A comprehensive nomenclature of proteoglycansEnhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactomeSimultaneous Binding of Two Peptidyl Ligands by a Src Homology 2 DomainDiverse Levels of Sequence Selectivity and Catalytic Efficiency of Protein-Tyrosine PhosphatasesAn investigation of hierachical protein recruitment to the inhibitory platelet receptor, G6B-bSHP-1 and SHP-2 in T cells: two phosphatases functioning at many levelsCompletion of proteomic data sets by Kd measurement using cell-free synthesis of site-specifically labeled proteins.Sequence specificity of SHP-1 and SHP-2 Src homology 2 domains. Critical roles of residues beyond the pY+3 position.Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries.Reverse interactomics: decoding protein-protein interactions with combinatorial peptide libraries.Synthesis and screening of a cyclic peptide library: discovery of small-molecule ligands against human prolactin receptorA combinatorial H4 tail library for exploring the histone code.High-throughput sequencing of peptoids and peptide-peptoid hybrids by partial edman degradation and mass spectrometry.On-bead screening of combinatorial libraries: reduction of nonspecific binding by decreasing surface ligand density.Robust production of a peptide library using methodological synchronizationThe role of Src homology 2 containing protein tyrosine phosphatase 2 in vascular smooth muscle cell migration and proliferation.Determination of the substrate specificity of protein-tyrosine phosphatase TULA-2 and identification of Syk as a TULA-2 substrate.Human-specific evolution and adaptation led to major qualitative differences in the variable receptors of human and chimpanzee natural killer cellsHDAC6 and Ubp-M BUZ domains recognize specific C-terminal sequences of proteins.Distinct ligand specificity of the Tiam1 and Tiam2 PDZ domainsSubstrate specificity of protein tyrosine phosphatases 1B, RPTPĪ±, SHP-1, and SHP-2.In vivo regulation of the allergic response by the IL-4 receptor alpha chain immunoreceptor tyrosine-based inhibitory motifDiverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromesDetermination of hemin-binding characteristics of proteins by a combinatorial peptide library approach.SHP-1 is a target of regorafenib in colorectal cancer.Functional requirements for inhibitory signal transmission by the immunomodulatory receptor CD300a.Regulation of hematopoietic cell function by inhibitory immunoglobulin G receptors and their inositol lipid phosphatase effectors.Direct Ras Inhibitors Identified from a Structurally Rigidified Bicyclic Peptide Library.The application of modular protein domains in proteomicsGlobal analysis of peptide cyclization efficiency.Specificity profiling of protein-binding domains using one-bead-one-compound Peptide libraries.Targeting protein tyrosine phosphatases for anticancer drug discovery.Profiling the substrate specificity of protein kinases by on-bead screening of peptide librariesBacterial effector activates jasmonate signaling by directly targeting JAZ transcriptional repressors.Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulationDeciphering Phosphotyrosine-Dependent Signaling Networks in Cancer by SH2 ProfilingSOCS3 drives proteasomal degradation of indoleamine 2,3-dioxygenase (IDO) and antagonizes IDO-dependent tolerogenesisBinding specificity of SH2 domains: insight from free energy simulations.Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity.Biophysical assay for tethered signaling reactions reveals tether-controlled activity for the phosphatase SHP-1.
P2860
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P2860
Decoding protein-protein interactions through combinatorial chemistry: sequence specificity of SHP-1, SHP-2, and SHIP SH2 domains.
description
2005 nĆ® lÅ«n-bĆ»n
@nan
2005 Õ©ÕøÖÕ”ÕÆÕ”Õ¶Õ« ÕÕøÕµÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕøÖÕ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ ÕµÖ
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@hyw
2005 Õ©Õ¾Õ”ÕÆÕ”Õ¶Õ« Õ¶ÕøÕµÕ„Õ“Õ¢Õ„ÖÕ«Õ¶ Õ°ÖÕ”ÕæÕ”ÖÕ”ÕÆÕ¾Õ”Õ® Õ£Õ«ÕæÕ”ÕÆÕ”Õ¶ Õ°ÕøÕ¤Õ¾Õ”Õ®
@hy
2005幓ć®č«ę
@ja
2005幓å¦ęÆęē«
@wuu
2005幓å¦ęÆęē«
@zh-cn
2005幓å¦ęÆęē«
@zh-hans
2005幓å¦ęÆęē«
@zh-my
2005幓å¦ęÆęē«
@zh-sg
2005幓åøč”ęē«
@yue
name
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@ast
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@en
type
label
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@ast
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@en
prefLabel
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@ast
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@en
P2093
P356
P1433
P1476
Decoding protein-protein inter ...... , SHP-2, and SHIP SH2 domains.
@en
P2093
Anne-Sophie Wavreille
Jonathan P Butchar
Junguk Park
Michael C Sweeney
Susheela Tridandapani
P304
14932-14947
P356
10.1021/BI051408H
P407
P577
2005-11-01T00:00:00Z