Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug.
about
Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity.A combined approach to data mining of textual and structured data to identify cancer-related targets.Fibroblast activation protein peptide substrates identified from human collagen I derived gelatin cleavage sites.Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer.Protease-activated drug development.Targeting the cancer stroma with a fibroblast activation protein-activated promelittin protoxinEndoplasmic reticulum calcium depletion impacts chaperone secretion, innate immunity, and phagocytic uptake of cellsTargeting carcinoma-associated fibroblasts within the tumor stroma with a fibroblast activation protein-activated prodrug.A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer.Development of peptides specifically modulating the activity of KLK2 and KLK3.Xanthane sesquiterpenoids: structure, synthesis and biological activity.Targeting kallikrein-related peptidases in prostate cancer.Kallikrein-related peptidases targeted therapies in prostate cancer: perspectives and challenges.Novel expression of kallikreins, kallikrein-related peptidases and kinin receptors in human pleural mesothelioma.Kallikrein-related peptidases (KLKs) as emerging therapeutic targets: focus on prostate cancer and skin pathologies.Protease-activated pore-forming peptides for the treatment and imaging of prostate cancerKLK-targeted Therapies for Prostate Cancer.The designer leptin antagonist peptide Allo-aca compensates for short serum half-life with very tight binding to the receptor.Evaluation of the tumor targeting of a FAPα-based doxorubicin prodrug.Perspectives on using physcomitrella patens as an alternative production platform for thapsigargin and other terpenoid drug candidates.
P2860
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P2860
Pharmacokinetics, biodistribution, and antitumor efficacy of a human glandular kallikrein 2 (hK2)-activated thapsigargin prodrug.
description
2006 nî lūn-bûn
@nan
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@ast
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@en
type
label
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@ast
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@en
prefLabel
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@ast
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@en
P2093
P356
P1433
P1476
Pharmacokinetics, biodistribut ...... ctivated thapsigargin prodrug.
@en
P2093
Craig A Dionne
D Marc Rosen
John T Isaacs
Rebecca M Ricklis
Samuel Janssen
Samuel R Denmeade
Soeren B Christensen
P304
P356
10.1002/PROS.20348
P50
P577
2006-03-01T00:00:00Z