The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.
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The mycobacterial 38-kilodalton glycolipoprotein antigen activates the mitogen-activated protein kinase pathway and release of proinflammatory cytokines through Toll-like receptors 2 and 4 in human monocytesMycobacterium tuberculosis lipoprotein LprG (Rv1411c) binds triacylated glycolipid agonists of Toll-like receptor 2Acylation determines the toll-like receptor (TLR)-dependent positive versus TLR2-, mannose receptor-, and SIGNR1-independent negative regulation of pro-inflammatory cytokines by mycobacterial lipomannanHemolytic phospholipase Rv0183 of Mycobacterium tuberculosis induces inflammatory response and apoptosis in alveolar macrophage RAW264.7 cellsNew insights into the biosynthesis of mycobacterial lipomannan arising from deletion of a conserved gene.PIM2 Induced COX-2 and MMP-9 expression in macrophages requires PI3K and Notch1 signalingA truncated lipoglycan from mycobacteria with altered immunological properties.Diversity in Mycobacterium tuberculosis mannosylated cell wall determinants impacts adaptation to the host.TLR2 engagement on CD4(+) T cells enhances effector functions and protective responses to Mycobacterium tuberculosis.Mycobacterial PIMs inhibit host inflammatory responses through CD14-dependent and CD14-independent mechanismsLipoglycans contribute to innate immune detection of mycobacteriaRegulation of antigen presentation by Mycobacterium tuberculosis: a role for Toll-like receptorsThe cell envelope glycoconjugates of Mycobacterium tuberculosisManipulation of the endocytic pathway and phagocyte functions by Mycobacterium tuberculosis lipoarabinomannan.Gram-positive bacterial lipoglycans based on a glycosylated diacylglycerol lipid anchor are microbe-associated molecular patterns recognized by TLR2Mycobacterial phosphatidylinositol mannoside 6 (PIM6) up-regulates TCR-triggered HIV-1 replication in CD4+ T cells.Lipoarabinomannan biosynthesis in Corynebacterineae: the interplay of two α(1→2)-mannopyranosyltransferases MptC and MptD in mannan branching.IL12B expression is sustained by a heterogenous population of myeloid lineages during tuberculosis.Lipoarabinomannan and related glycoconjugates: structure, biogenesis and role in Mycobacterium tuberculosis physiology and host-pathogen interactionAc2PIM-responsive miR-150 and miR-143 target receptor-interacting protein kinase 2 and transforming growth factor beta-activated kinase 1 to suppress NOD2-induced immunomodulators.Structural determination and Toll-like receptor 2-dependent proinflammatory activity of dimycolyl-diarabino-glycerol from Mycobacterium marinumIn vitro immunomodulation of a whole blood IFN-γ release assay enhances T cell responses in subjects with latent tuberculosis infection.Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiationStructural characterization and functional properties of a novel lipomannan variant isolated from a Corynebacterium glutamicum pimB' mutant.Mycobacterium avium glycopeptidolipids require specific acetylation and methylation patterns for signaling through toll-like receptor 2.Lipids derived from virulent Francisella tularensis broadly inhibit pulmonary inflammation via toll-like receptor 2 and peroxisome proliferator-activated receptor α.Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.Disruption of Mycobacterial AftB Results in Complete Loss of Terminal β(1 → 2) Arabinofuranose Residues of Lipoarabinomannan.A GMC oxidoreductase homologue is required for acetylation of glycopeptidolipid in Mycobacterium smegmatis.The role of eosinophils in non-parasitic infections.Glycopeptidolipids: immuno-modulators in greasy mycobacterial cell envelope.Outcome of Mycobacterium tuberculosis and Toll-like receptor interaction: immune response or immune evasion?Soluble human TLR2 ectodomain binds diacylglycerol from microbial lipopeptides and glycolipids.Immunomodulatory effects of heat-killed Mycobacterium obuense on human blood dendritic cells.Upregulation of PIM2 by Underexpression of MicroRNA-135-5p Improves Survival Rates of Skin Allografts by Suppressing Apoptosis of Fibroblast Cells.The Goldilocks model of immune symbiosis with Mycobacteria and Candida colonizers.A network of hydrogen bonds on the surface of TLR2 controls ligand positioning and cell signaling.Toll-like receptor 3 activation selectively reverses HIV latency in microglial cells.Mycobacterial phosphatidylinositol mannosides negatively regulate host Toll-like receptor 4, MyD88-dependent proinflammatory cytokines, and TRIF-dependent co-stimulatory molecule expression.Mycobacteria exploit nitric oxide-induced transformation of macrophages into permissive giant cells.
P2860
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P2860
The acylation state of mycobacterial lipomannans modulates innate immunity response through toll-like receptor 2.
description
2006 nî lūn-bûn
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2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
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2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
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2006年论文
@wuu
name
The acylation state of mycobac ...... through toll-like receptor 2.
@ast
The acylation state of mycobac ...... through toll-like receptor 2.
@en
type
label
The acylation state of mycobac ...... through toll-like receptor 2.
@ast
The acylation state of mycobac ...... through toll-like receptor 2.
@en
prefLabel
The acylation state of mycobac ...... through toll-like receptor 2.
@ast
The acylation state of mycobac ...... through toll-like receptor 2.
@en
P50
P1476
The acylation state of mycobac ...... through toll-like receptor 2.
@en
P2093
Delphine Nicolle
P356
10.1016/J.CHEMBIOL.2005.10.013
P577
2006-01-01T00:00:00Z