A methodology for the structural and functional analysis of signaling and regulatory networks.
about
Structural and functional analysis of cellular networks with CellNetAnalyzerThe smallest chemical reaction system with bistabilitySBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and toolsData-driven integration of genome-scale regulatory and metabolic network modelsON/OFF and beyond--a boolean model of apoptosisTraining signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuliStructural and logical analysis of a comprehensive hedgehog signaling pathway to identify alternative drug targets for glioma, colon and pancreatic cancerComprehensive logic based analyses of Toll-like receptor 4 signal transduction pathwayNetwork reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theoryCurrent approaches to gene regulatory network modellingPredicting biological system objectives de novo from internal state measurements.Application of Petri net based analysis techniques to signal transduction pathways.Modularization of biochemical networks based on classification of Petri net t-invariants.Adapted Boolean network models for extracellular matrix formation.CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms.Detecting and removing inconsistencies between experimental data and signaling network topologies using integer linear programming on interaction graphs.Extended notions of sign consistency to relate experimental data to signaling and regulatory network topologies.PATHLOGIC-S: a scalable Boolean framework for modelling cellular signallingDynamics of p53 and NF-κB regulation in response to DNA damage and identification of target proteins suitable for therapeutic intervention.Visual setup of logical models of signaling and regulatory networks with ProMoT.SigFlux: a novel network feature to evaluate the importance of proteins in signal transduction networks.A logical model provides insights into T cell receptor signaling.Pathway switching explains the sharp response characteristic of hypoxia response network.Dynamic simulation of regulatory networks using SQUADHost-pathogen systems biology: logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transductionTemporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle.Exact model reduction of combinatorial reaction networks.Robust simplifications of multiscale biochemical networksReconstructing generalized logical networks of transcriptional regulation in mouse brain from temporal gene expression dataHypergraphs and cellular networks.Computing paths and cycles in biological interaction graphs.The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput dataTransforming Boolean models to continuous models: methodology and application to T-cell receptor signaling.Monotonicity, frustration, and ordered response: an analysis of the energy landscape of perturbed large-scale biological networks.MEIGO: an open-source software suite based on metaheuristics for global optimization in systems biology and bioinformatics.Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction.Elementary signaling modes predict the essentiality of signal transduction network components.A systems approach to identifying correlated gene targets for the loss of colour pigmentation in plants.Inference of complex biological networks: distinguishability issues and optimization-based solutions.
P2860
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P2860
A methodology for the structural and functional analysis of signaling and regulatory networks.
description
2006 nî lūn-bûn
@nan
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
A methodology for the structur ...... aling and regulatory networks.
@ast
A methodology for the structur ...... aling and regulatory networks.
@en
type
label
A methodology for the structur ...... aling and regulatory networks.
@ast
A methodology for the structur ...... aling and regulatory networks.
@en
prefLabel
A methodology for the structur ...... aling and regulatory networks.
@ast
A methodology for the structur ...... aling and regulatory networks.
@en
P2093
P2860
P356
P1433
P1476
A methodology for the structur ...... aling and regulatory networks.
@en
P2093
Ernst D Gilles
Jonathan A Lindquist
Luca Simeoni
P2860
P2888
P356
10.1186/1471-2105-7-56
P577
2006-02-07T00:00:00Z
P5875
P6179
1027050639