Development of selective inhibitors and substrate of matrix metalloproteinase-12. - Wikidata - awgldk - TriplyDB

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

http://www.wikidata.org/entity/Q33234060

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Solution Structure of Inhibitor-Free Human Metalloelastase (MMP-12) Indicates an Internal Conformational Adjustment Insights from Selective Non-phosphinic Inhibitors of MMP-12 Tailored to Fit with an S1' Loop Canonical Conformation Simple Pseudo-dipeptides with a P2' Glutamate: A NOVEL INHIBITOR FAMILY OF MATRIX METALLOPROTEASES AND OTHER METZINCINS Sugar-Based Arylsulfonamide Carboxylates as Selective and Water-Soluble Matrix Metalloproteinase-12 Inhibitors Synthesis and in Vitro and in Vivo Evaluation of MMP-12 Selective Optical Probes Radiolabelled probes for imaging of atherosclerotic plaques.Using specificity to strategically target proteases.Upregulation of elastase activity in aorta in mucopolysaccharidosis I and VII dogs may be due to increased cytokine expression.Trophoblast- and vascular smooth muscle cell-derived MMP-12 mediates elastolysis during uterine spiral artery remodeling.A selective matrix metalloproteinase-12 inhibitor retards atherosclerotic plaque development in apolipoprotein E-knockout mice.In vivo imaging of matrix metalloproteinase 12 and matrix metalloproteinase 13 activities in the mouse model of collagen-induced arthritis.A single freeze-thawing cycle for highly efficient solubilization of inclusion body proteins and its refolding into bioactive form Sensitivity of heterozygous α1,6-fucosyltransferase knock-out mice to cigarette smoke-induced emphysema: implication of aberrant transforming growth factor-β signaling and matrix metalloproteinase gene expression Investigating the Selectivity of Metalloenzyme Inhibitors in the Presence of Competing Metalloproteins.Synthesis of Fmoc-Gly-Ile Phosphinic Pseudodipeptide: Residue Specific Conditions for Construction of Matrix Metalloproteinase Inhibitor Building Blocks Cysteine protease cathepsins and matrix metalloproteinases in the development of abdominal aortic aneurysms.Triple-helical transition state analogues: a new class of selective matrix metalloproteinase inhibitors.Metalloproteinases and vulnerable atherosclerotic plaques Upregulation of elastase proteins results in aortic dilatation in mucopolysaccharidosis I mice.Investigating the selectivity of metalloenzyme inhibitors.Chemical biology for understanding matrix metalloproteinase function.Targeting matrix metalloproteinase activity and expression for the treatment of viral myocarditis.Photoactivated Spatiotemporally-Responsive Nanosensors of in Vivo Protease Activity.MMP-12, a Promising Therapeutic Target for Neurological Diseases.Molecular design of a highly selective and strong protein inhibitor against matrix metalloproteinase-2 (MMP-2).Matrix metalloproteases-responsive nanomaterials for tumor targeting diagnosis and treatment.Target-Activated Prodrugs (TAPs) for the Autoregulated Inhibition of MMP12.Discovery of a New Class of Potent MMP Inhibitors by Structure-Based Optimization of the Arylsulfonamide Scaffold.Matrix Metalloproteinase-Targeted Imaging of Lung Inflammation and Remodeling Detection of endogenous matrix metalloprotease-12 active form with a novel broad spectrum activity-based probe TGF-beta activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II-infused mice.Molecular determinants of matrix metalloproteinase-12 covalent modification by a photoaffinity probe: insights into activity-based probe development and conformational variability of matrix metalloproteinases.Optical imaging of MMP-12 active form in inflammation and aneurysm.New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.Therapeutic Potential of Matrix Metalloproteinase Inhibition in Breast Cancer.Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1.Preclinical Evaluation of RYM1, a Matrix Metalloproteinase-Targeted Tracer for Imaging Aneurysm.Effects of selective MMP-13 inhibition in squamous cell carcinoma depend on estrogen.Pd-catalyzed carbonylative access to aroyl phosphonates from (hetero)aryl bromides.Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, Tc-labeling, and Evaluation

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P2860

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

http://www.wikidata.org/entity/Q33234060

description

2006 nî lūn-bûn

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2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի փետրվարին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

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Development of selective inhibitors and substrate of matrix metalloproteinase-12.

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type

label

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

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Development of selective inhibitors and substrate of matrix metalloproteinase-12.

@en

prefLabel

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

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Development of selective inhibitors and substrate of matrix metalloproteinase-12.

@en

P1433

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P1433

Journal of Biological Chemistry

P1476

Development of selective inhibitors and substrate of matrix metalloproteinase-12.

@en

P2093

Anastasios Makaritis

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Arnaud David

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Athanasios Yiotakis

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Fabrice Beau

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Laurent Devel

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Philippe Cuniasse

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Vassilis Rogakos

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Vincent Dive

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P2860

Expression and localization of macrophage elastase (matrix metalloproteinase-12) in abdominal aortic aneurysms

Crystal structure of the stromelysin-3 (MMP-11) catalytic domain complexed with a phosphinic inhibitor mimicking the transition-state

All-atom empirical potential for molecular modeling and dynamics studies of proteins

Dysregulation of TGF-beta1 receptor activation leads to abnormal lung development and emphysema-like phenotype in core fucose-deficient mice

Matrix Metalloproteinase Inhibitors and Cancer--Trials and Tribulations

New functions for the matrix metalloproteinases in cancer progression

Structural basis for the highly selective inhibition of MMP-13.

Matrix metalloproteinases: a tail of a frog that became a prince.

Conformational variability of matrix metalloproteinases: beyond a single 3D structure.

Divergent effects of matrix metalloproteinases 3, 7, 9, and 12 on atherosclerotic plaque stability in mouse brachiocephalic arteries.

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11152-11160

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scholarly article

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10.1074/JBC.M600222200

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16

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P478

281

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2006-02-15T00:00:00Z

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P698

16481329

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