Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets

Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets

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http://www.wikidata.org/entity/Q33245746
Cooperative enhancement of deoxyribozyme activity by chemical modification and added cationic copolymerA microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinoma.Efficient inhibition of HIV-1 expression by LNA modified antisense oligonucleotides and DNAzymes targeted to functionally selected binding sites.C5-alkynyl-functionalized α-L-LNA: synthesis, thermal denaturation experiments and enzymatic stabilityFunctionalized 2'-amino-alpha-L-LNA: directed positioning of intercalators for DNA targeting.Depletion of unwanted nucleic acid templates by selective cleavage: LNAzymes, catalytically active oligonucleotides containing locked nucleic acids, open a new window for detecting rare microbial community membersDeoxyribozymes and bioinformatics: complementary tools to investigate axon regeneration.Site-specific cleavage of mutant ABL mRNA by DNAzyme is facilitated by peptide nucleic acid binding to RNA substrate.Novel Chemically-modified DNAzyme targeting Integrin alpha-4 RNA transcript as a potential molecule to reduce inflammation in multiple sclerosis.Inability of DNAzymes to cleave RNA in vivo is due to limited Mg[Formula: see text] concentration in cells.The advantages of being locked. Assessing the cleavage of short and long RNAs by locked nucleic acid-containing 8-17 deoxyribozymes.
P2860

Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets

Item
http://www.wikidata.org/entity/Q33245746
description
2006 nî lūn-bûn
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2006 թուականի Յունիսին հրատարակուած գիտական յօդուած
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2006 թվականի հունիսին հրատարակված գիտական հոդված
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2006年の論文
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2006年論文
@yue
2006年論文
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2006年論文
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2006年論文
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2006年論文
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2006年论文
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name
Locked nucleoside analogues ex ...... cleave structured RNA targets
@ast
Locked nucleoside analogues ex ...... cleave structured RNA targets
@en
type
label
Locked nucleoside analogues ex ...... cleave structured RNA targets
@ast
Locked nucleoside analogues ex ...... cleave structured RNA targets
@en
prefLabel
Locked nucleoside analogues ex ...... cleave structured RNA targets
@ast
Locked nucleoside analogues ex ...... cleave structured RNA targets
@en
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P478
P50
P577
P5875
P6179
P698
P932
P356
P1433
P1476
Locked nucleoside analogues ex ...... cleave structured RNA targets
@en
P2093
P2860
P2888
P304
P31
P356
P478
P50
P577
P5875
P6179
P698
P932