Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3.
about
Metformin protects cardiomyocyte from doxorubicin induced cytotoxicity through an AMP-activated protein kinase dependent signaling pathway: an in vitro studyMetformin as a cellular protector; a synoptic view of modern evidencesAMP-activated protein kinase confers protection against TNF-{alpha}-induced cardiac cell death.Treatment with the 3-ketoacyl-CoA thiolase inhibitor trimetazidine does not exacerbate whole-body insulin resistance in obese mice.The vestigial enzyme D-dopachrome tautomerase protects the heart against ischemic injury.Cytosolic, but not mitochondrial, oxidative stress is a likely contributor to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in miceMetformin inhibits growth of lung adenocarcinoma cells by inducing apoptosis via the mitochondria-mediated pathway.AMP-regulated protein kinase activity in the hearts of mice treated with low- or high-fat diet measured using novel LC-MS method.AMPK/mTOR-mediated inhibition of survivin partly contributes to metformin-induced apoptosis in human gastric cancer cellNonischemic heart failure in diabetes mellitus.Sphingolipids, insulin resistance, and metabolic disease: new insights from in vivo manipulation of sphingolipid metabolism.Magnolia extract (BL153) protection of heart from lipid accumulation caused cardiac oxidative damage, inflammation, and cell death in high-fat diet fed mice.The potential role of sphingolipid-mediated cell signaling in the interaction between hyperglycemia, acute myocardial infarction and heart failure.AMP-activated protein kinase regulation and biological actions in the heart.The impact of current and novel anti-diabetic therapies on cardiovascular risk.FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival.Fatty acid metabolism in pulmonary arterial hypertension: role in right ventricular dysfunction and hypertrophy.Punicalagin induces apoptotic and autophagic cell death in human U87MG glioma cells.The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.Inhibition of serine palmitoyl transferase I reduces cardiac ceramide levels and increases glycolysis rates following diet-induced insulin resistance.Metformin exerts antitumor activity via induction of multiple death pathways in tumor cells and activation of a protective immune response.Metabolic Effects of Metformin in the Failing Heart
P2860
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P2860
Metformin influences cardiomyocyte cell death by pathways that are dependent and independent of caspase-3.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Metformin influences cardiomyo ...... and independent of caspase-3.
@ast
Metformin influences cardiomyo ...... and independent of caspase-3.
@en
type
label
Metformin influences cardiomyo ...... and independent of caspase-3.
@ast
Metformin influences cardiomyo ...... and independent of caspase-3.
@en
prefLabel
Metformin influences cardiomyo ...... and independent of caspase-3.
@ast
Metformin influences cardiomyo ...... and independent of caspase-3.
@en
P2093
P2860
P1433
P1476
Metformin influences cardiomyo ...... and independent of caspase-3.
@en
P2093
Abrahani A
Kewalramani G
Rodrigues B
P2860
P2888
P304
P356
10.1007/S00125-006-0338-9
P577
2006-07-26T00:00:00Z
P5875
P6179
1023565310