Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand.
about
Melanoma and the Unfolded Protein ResponseRational approaches to improving selectivity in drug designCancer cells resistant to therapy promote cell surface relocalization of GRP78 which complexes with PI3K and enhances PI(3,4,5)P3 productionGRP78(BiP) facilitates the cytosolic delivery of anthrax lethal factor (LF) in vivo and functions as an unfoldase in vitro.Radiation-induced tumor neoantigens: imaging and therapeutic implications.Near-infrared-labeled peptide multimer functions as phage mimic for high affinity, specific targeting of colonic adenomas in vivo (with videos).Combinatorial peptide libraries: mining for cell-binding peptides.Biopanning of phage displayed peptide libraries for the isolation of cell-specific ligandsPeptidic tumor targeting agents: the road from phage display peptide selections to clinical applications.Potential of phage-displayed peptide library technology to identify functional targeting peptidesIdentification of peptide ligands for targeting to the blood-brain barrierPhage display in molecular imaging and diagnosis of cancer.Maurocalcine as a non toxic drug carrier overcomes doxorubicin resistance in the cancer cell line MDA-MB 231Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.Targeted nanoparticles that deliver a sustained, specific release of Paclitaxel to irradiated tumors.Identification of a LNCaP-specific binding peptide using phage display.Landscape phages and their fusion proteins targeted to breast cancer cells.Identification of a novel lysosomal trafficking peptide using phage display biopanning coupled with endocytic selection pressurePhage display--a powerful technique for immunotherapy: 1. Introduction and potential of therapeutic applications.A peptidic unconjugated GRP78/BiP ligand modulates the unfolded protein response and induces prostate cancer cell deathSynthesis, Surface Studies, Composition and Structural Characterization of CdSe, Core/Shell, and Biologically Active Nanocrystals.Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78.Synthesis, characterization, and biological activity of poly(arginine)-derived cancer-targeting peptides in HepG2 liver cancer cells.Selection and identification of ligand peptides targeting a model of castrate-resistant osteogenic prostate cancer and their receptors.Synthesis and biological evaluation of a peptide-paclitaxel conjugate which targets the integrin αvβ₆GRP78 Protein Expression in Ovarian Cancer Patients and Perspectives for a Drug-Targeting Approach.Blockade of GRP78 sensitizes breast cancer cells to microtubules-interfering agents that induce the unfolded protein response.Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targetingTumor-targeting peptides from combinatorial libraries.A cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy.Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors.Potential tumor biomarkers identified in ovarian cyst fluid by quantitative proteomic analysis, iTRAQ.Probing the ATP Site of GRP78 with Nucleotide Triphosphate Analogs.Mechanistic studies of a peptidic GRP78 ligand for cancer cell-specific drug delivery.The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesDesign of virus-based nanomaterials for medicine, biotechnology, and energy.A comparison of peptide and folate receptor targeting of cancer cells: from single agent to nanoparticle.Targeting GRP78 and antiestrogen resistance in breast cancer.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potentialAntibody Engineering for Pursuing a Healthier Future
P2860
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P2860
Targeting heat shock proteins on cancer cells: selection, characterization, and cell-penetrating properties of a peptidic GRP78 ligand.
description
2006 nî lūn-bûn
@nan
2006 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@ast
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@en
type
label
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@ast
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@en
prefLabel
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@ast
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@en
P2093
P50
P356
P1433
P1476
Targeting heat shock proteins ...... es of a peptidic GRP78 ligand.
@en
P2093
Antonietta M Lillo
Brunhilde Felding-Habermann
Gunnar F Kaufmann
Kim D Janda
Sebastian C J Steiniger
Youngsoo Kim
P304
P356
10.1021/BI060264J
P407
P577
2006-08-01T00:00:00Z