An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF. - Wikidata - awgldk - TriplyDB

An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF.

An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF.

http://www.wikidata.org/entity/Q33257634

about

Novel Chemical Ligands to Ebola Virus and Marburg Virus Nucleoproteins Identified by Combining Affinity Mass Spectrometry and Metabolomics Approaches Phage display-derived inhibitor of the essential cell wall biosynthesis enzyme MurF.Review article: high-throughput affinity-based technologies for small-molecule drug discovery.Studies of metabolite-protein interactions: a review Recent developments in protein-ligand affinity mass spectrometry.Screening a fragment cocktail library using ultrafiltration.Affinity-based screening techniques: their impact and benefit to increase the number of high quality leads.Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with bioassays.Application of high-throughput affinity-selection mass spectrometry for screening of chemical compound libraries in lead discovery.A ligand-observed mass spectrometry approach integrated into the fragment based lead discovery pipeline.Investigating metabolite-protein interactions: an overview of available techniques.Screening of tobacco smoke condensate for nicotinic acetylcholine receptor ligands using cellular membrane affinity chromatography columns and missing peak chromatography.Cytoplasmic steps of peptidoglycan biosynthesis.Insight into the structural requirements of thiophene-3-carbonitriles-based MurF inhibitors by 3D-QSAR, molecular docking and molecular dynamics study.Analysis of high-throughput screening assays using cluster enrichment.Rapid LC-MS Based High-Throughput Screening Method, Affording No False Positives or False Negatives, Identifies a New Inhibitor for Carbonic Anhydrase.A novel assay of bacterial peptidoglycan synthesis for natural product screening.BoBER: web interface to the base of bioisosterically exchangeable replacements.

P2860

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P2860

An ultraefficient affinity-based high-throughout screening process: application to bacterial cell wall biosynthesis enzyme MurF.

http://www.wikidata.org/entity/Q33257634

description

2006 nî lūn-bûn

@nan

2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

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P1433

Journal of Biomolecular Screening

P1476

An ultraefficient affinity-bas ...... wall biosynthesis enzyme MurF.

@en

P2093

Bruce A Beutel

http://www.w3.org/2001/XMLSchema#string

Claude G Lerner

http://www.w3.org/2001/XMLSchema#string

David J Burns

http://www.w3.org/2001/XMLSchema#string

Houjun Yang

http://www.w3.org/2001/XMLSchema#string

Hua Tang

http://www.w3.org/2001/XMLSchema#string

J Owen McCall

http://www.w3.org/2001/XMLSchema#string

Jonathan D Trumbull

http://www.w3.org/2001/XMLSchema#string

Kenneth M Comess

http://www.w3.org/2001/XMLSchema#string

Lan Gao

http://www.w3.org/2001/XMLSchema#string

Mark E Schurdak

http://www.w3.org/2001/XMLSchema#string

P2860

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

Structure of MurF from Streptococcus pneumoniae co-crystallized with a small molecule inhibitor exhibits interdomain closure

Hit and lead generation: beyond high-throughput screening

Do structurally similar molecules have similar biological activity?

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

High-density miniaturized thermal shift assays as a general strategy for drug discovery

MS/NMR: a structure-based approach for discovering protein ligands and for drug design by coupling size exclusion chromatography, mass spectrometry, and nuclear magnetic resonance spectroscopy.

Early discovery drug screening using mass spectrometry.

Analysis and screening of combinatorial libraries using mass spectrometry.

Structure-based screening as applied to human FABP4: a highly efficient alternative to HTS for hit generation.

P304

743-754

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7

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11

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