Macular degeneration: recent advances and therapeutic opportunities.
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesGlycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics)Retinopathy in mice induced by disrupted all-trans-retinal clearanceCellular and molecular mechanisms of fibrosisSelective survival rescue in 15-lipoxygenase-1-deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1Generation of reactive oxygen species in the anterior eye segment. Synergistic codrugs of N-acetylcarnosine lubricant eye drops and mitochondria-targeted antioxidant act as a powerful therapeutic platform for the treatment of cataracts and primary oMechanisms of age-related macular degenerationRoles for the ubiquitin-proteasome pathway in protein quality control and signaling in the retina: implications in the pathogenesis of age-related macular degenerationPerturbing the ubiquitin pathway reveals how mitosis is hijacked to denucleate and regulate cell proliferation and differentiation in vivoIron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseasesIKK2 inhibition attenuates laser-induced choroidal neovascularizationMitochondrial function and redox control in the aging eye: role of MsrA and other repair systems in cataract and macular degenerationsAge-related neuronal loss in the cochlea is not delayed by synaptic modulation.Anti-epileptic drugs delay age-related loss of spiral ganglion neurons via T-type calcium channel.Age-related loss of spiral ganglion neuronsAge-related synaptic loss of the medial olivocochlear efferent innervationA detailed three-step protocol for live imaging of intracellular traffic in polarized primary porcine RPE monolayersGeneration of retinal ganglion cells with functional axons from human induced pluripotent stem cells.The aged retinal pigment epithelium/choroid: a potential substratum for the pathogenesis of age-related macular degeneration.Bone marrow-derived mesenchymal cells and MMP13 contribute to experimental choroidal neovascularization.Effect of g protein-coupled receptor kinase 1 (Grk1) overexpression on rod photoreceptor cell viabilityRetinoids for treatment of retinal diseasesRescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1.Ubiquitin proteasome pathway-mediated degradation of proteins: effects due to site-specific substrate deamidationDocosahexaenoic acid signalolipidomics in nutrition: significance in aging, neuroinflammation, macular degeneration, Alzheimer's, and other neurodegenerative diseases.Cell-penetrating peptide for enhanced delivery of nucleic acids and drugs to ocular tissues including retina and corneaDefective lipid transport and biosynthesis in recessive and dominant Stargardt macular degenerationGenetic basis of inherited macular dystrophies and implications for stem cell therapy.Studying age-related macular degeneration using animal models.Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration.Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.Age-related macular degeneration: genetic and environmental factors of diseaseStepwise differentiation of pluripotent stem cells into retinal cells.New findings in ATP supply in rod outer segments: insights for retinopathies.Light filtering in a retinal pigment epithelial cell culture model.Ubiquitin-proteasome pathway and cellular responses to oxidative stress.Baicalin attenuates laser-induced choroidal neovascularization.The role of Vldlr in intraretinal angiogenesis in mice.Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases.RPE-secreted factors: influence differentiation in human retinal cell line in dose- and density-dependent manner.
P2860
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P2860
Macular degeneration: recent advances and therapeutic opportunities.
description
2006 nî lūn-bûn
@nan
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Macular degeneration: recent advances and therapeutic opportunities.
@ast
Macular degeneration: recent advances and therapeutic opportunities.
@en
Macular degeneration: recent advances and therapeutic opportunities.
@nl
type
label
Macular degeneration: recent advances and therapeutic opportunities.
@ast
Macular degeneration: recent advances and therapeutic opportunities.
@en
Macular degeneration: recent advances and therapeutic opportunities.
@nl
prefLabel
Macular degeneration: recent advances and therapeutic opportunities.
@ast
Macular degeneration: recent advances and therapeutic opportunities.
@en
Macular degeneration: recent advances and therapeutic opportunities.
@nl
P2860
P356
P1476
Macular degeneration: recent advances and therapeutic opportunities
@en
P2860
P2888
P304
P356
10.1038/NRN2007
P407
P577
2006-10-11T00:00:00Z
P6179
1011150149