Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers. - Wikidata - awgldk - TriplyDB

Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers.

Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers.

http://www.wikidata.org/entity/Q33260375

about

ZNF703 gene amplification at 8p12 specifies luminal B breast cancer ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression Co-amplified genes at 8p12 and 11q13 in breast tumors cooperate with two major pathways in oncogenesis Targeting RTK Signaling Pathways in Cancer Functional roles of fibroblast growth factor receptors (FGFRs) signaling in human cancers RCP is a human breast cancer-promoting gene with Ras-activating function Human cancer long non-coding RNA transcriptomes.An integrated analysis of genes and pathways exhibiting metabolic differences between estrogen receptor positive breast cancer cells.Prediction of potential cancer-risk regions based on transcriptome data: towards a comprehensive view Genome profiling of ERBB2-amplified breast cancers.DNA copy numbers profiles in affinity-purified ovarian clear cell carcinoma RNA-binding protein RNPC1: acting as a tumor suppressor in breast cancer.Characterization of genetic rearrangements in esophageal squamous carcinoma cell lines by a combination of M-FISH and array-CGH: further confirmation of some split genomic regions in primary tumors.The FGF/FGFR axis as a therapeutic target in breast cancer.Fibroblastic growth factor receptor 1 amplification in osteosarcoma is associated with poor response to neo-adjuvant chemotherapy.Rationale for targeting fibroblast growth factor receptor signaling in breast cancer Binding of pro-prion to filamin A: by design or an unfortunate blunder Lymphovascular invasion and histologic grade are associated with specific genomic profiles in invasive carcinomas of the breast Copy number imbalances between screen- and symptom-detected breast cancers and impact on disease-free survival.Genome-wide copy number alterations in subtypes of invasive breast cancers in young white and African American women.Elevated ZNF703 Protein Expression Is an Independent Unfavorable Prognostic Factor for Survival of the Patients with Head and Neck Squamous Cell Carcinoma Multiple gene aberrations and breast cancer: lessons from super-responders.Assessment of palindromes as platforms for DNA amplification in breast cancer Mammary tumorigenesis induced by fibroblast growth factor receptor 1 requires activation of the epidermal growth factor receptor.FGFR1 amplification in breast carcinomas: a chromogenic in situ hybridisation analysis.Challenges and opportunities in the targeting of fibroblast growth factor receptors in breast cancer.FGFR1 amplification in squamous cell carcinoma of the lung.Macrophages promote fibroblast growth factor receptor-driven tumor cell migration and invasion in a CXCR2-dependent manner.Fibroblast growth factor receptor-1 protein expression is associated with prognosis in estrogen receptor-positive/human epidermal growth factor receptor-2-negative primary breast cancer.FGFR1 is amplified during the progression of in situ to invasive breast carcinoma Integrated genomic analysis of breast cancers.Integrated analysis of breast cancer cell lines reveals unique signaling pathways.High expression of ZNF703 independent of amplification indicates worse prognosis in patients with luminal B breast cancer Genomic amplicons target vesicle recycling in breast cancer.Fluorescence in situ hybridization (FISH): an increasingly demanded tool for biomarker research and personalized medicine Aurora Kinase A Is a Prognostic Marker in Colorectal Adenocarcinoma.Genomic architecture characterizes tumor progression paths and fate in breast cancer patients.Basal phenotype breast cancer: implications for treatment and prognosis.Fibroblast growth factors and their receptors in cancer.

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Frequency, prognostic impact, and subtype association of 8p12, 8q24, 11q13, 12p13, 17q12, and 20q13 amplifications in breast cancers.

http://www.wikidata.org/entity/Q33260375

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2006 nî lūn-bûn

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P2860

Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma

C-myc, not HER-2/neu, can predict recurrence and mortality of patients with node-negative breast cancer

Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

Molecular portraits of human breast tumours

Repeated observation of breast tumor subtypes in independent gene expression data sets

A putative serine/threonine kinase encoding gene BTAK on chromosome 20q13 is amplified and overexpressed in human breast cancer cell lines

Independent amplification and frequent co-amplification of three nonsyntenic regions on the long arm of chromosome 20 in human breast cancer

Efficacy and safety of trastuzumab as a single agent in first-line treatment of HER2-overexpressing metastatic breast cancer

Tissue microarrays for high-throughput molecular profiling of tumor specimens

Pathogenesis of testicular germ cell tumours.

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