Colchicine glycorandomization influences cytotoxicity and mechanism of action.
about
Natural product disaccharide engineering through tandem glycosyltransferase catalysis reversibility and neoglycosylationEnzymatic methods for glyco(diversification/randomization) of drugs and small moleculesNatural-product sugar biosynthesis and enzymatic glycodiversification.Enhancing the divergent activities of betulinic acid via neoglycosylation.Azides derived from colchicine and their use in library synthesis: A practical entry to new bioactive derivatives of an old natural drug.Optimizing glycosyltransferase specificity via "hot spot" saturation mutagenesis presents a catalyst for novobiocin glycorandomization.Assessment of chemoselective neoglycosylation methods using chlorambucil as a model.Neoglycosylation and neoglycorandomization: Enabling tools for the discovery of novel glycosylated bioactive probes and early stage leads.High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity.The identification of perillyl alcohol glycosides with improved antiproliferative activityProbing the aglycon promiscuity of an engineered glycosyltransferaseEnhancement of cyclopamine via conjugation with nonmetabolic sugarsEnzymatic Biosynthesis of Novel Resveratrol Glucoside and Glycoside Derivatives.The impact of enzyme engineering upon natural product glycodiversificationGlycosyloxyamine neoglycosylation: a model study using calicheamicin.Warfarin glycosylation invokes a switch from anticoagulant to anticancer activity.5-Thiocyanato-2'-deoxyuridine as a possible radiosensitizer: electron-induced formation of uracil-C5-thiyl radical and its dimerization.Expression Patterns of Three UGT Genes in Different Chemotype Safflower Lines and under MeJA Stimulus Revealed Their Potential Role in Flavonoid BiosynthesisDirect synthesis of β-N-glycosides by the reductive glycosylation of azides with protected and native carbohydrate donors.Increasing carbohydrate diversity via amine oxidation: aminosugar, hydroxyaminosugar, nitrososugar, and nitrosugar biosynthesis in bacteriaProbing 3-hydroxyflavone for in vitro glycorandomization of flavonols by YjiC.Synthesis and antibacterial activity of doxycycline neoglycosides.Introducing N-glycans into natural products through a chemoenzymatic approach.Improvement of the pharmacological activity of menthol via enzymatic β-anomer-selective glycosylation.Microbial production of astilbin, a bioactive rhamnosylated flavanonol, from taxifolin.Chemoselective Reactions for the Synthesis of Glycoconjugates from Unprotected Carbohydrates.Design, synthesis, and anti-tobacco mosaic virus (TMV) activity of glycoconjugates of phenanthroindolizidines alkaloids.A fused [3.3.0]-neoglycoside lactone derived from glucuronic acid.Colchicine metallocenyl bioconjugates showing high antiproliferative activities against cancer cell lines.Peptide purification using the chemoselective reaction between N-(methoxy)glycine and isothiocyanato-functionalized resin.Broadening deoxysugar glycodiversity: natural and engineered transaldolases unlock a complementary substrate space.
P2860
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P2860
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
description
2006 nî lūn-bûn
@nan
2006 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@ast
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@en
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@nl
type
label
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@ast
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@en
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@nl
prefLabel
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@ast
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@en
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@nl
P2093
P356
P1476
Colchicine glycorandomization influences cytotoxicity and mechanism of action.
@en
P2093
Aqeel Ahmed
F Michael Hoffmann
James A Watson
Megan K Fitzgerald
Noël R Peters
P304
14224-14225
P356
10.1021/JA064686S
P407
P577
2006-11-01T00:00:00Z