Improved nuclear localization of DNA-binding polyamides. - Wikidata - awgldk - TriplyDB

Improved nuclear localization of DNA-binding polyamides.

Improved nuclear localization of DNA-binding polyamides.

http://www.wikidata.org/entity/Q33266897

about

Suppression of androgen receptor-mediated gene expression by a sequence-specific DNA-binding polyamide Allosteric modulation of DNA by small molecules Structural Basis for Cyclic Py-Im Polyamide Allosteric Inhibition of Nuclear Receptor Binding Inhibiting gene expression with locked nucleic acids (LNAs) that target chromosomal DNA.Next generation hairpin polyamides with (R)-3,4-diaminobutyric acid turn unit.Quantitating the concentration of Py-Im polyamide-fluorescein conjugates in live cells Rational design of ligands targeting triplet repeating transcripts that cause RNA dominant disease: application to myotonic muscular dystrophy type 1 and spinocerebellar ataxia type 3.Modifications at the C-terminus to improve pyrrole-imidazole polyamide activity in cell culture.Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides.Binding studies of a large antiviral polyamide to a natural HPV sequence.HPV episome levels are potently decreased by pyrrole-imidazole polyamides.A C-14 labeled Py-Im polyamide localizes to a subcutaneous prostate cancer tumor.DNA-binding small molecules as inhibitors of transcription factors.Progress and prospects of pyrrole-imidazole polyamide-fluorophore conjugates as sequence-selective DNA probes.Noncanonical mechanisms to regulate nuclear receptor signaling.Controlling gene networks and cell fate with precision-targeted DNA-binding proteins and small-molecule-based genome readers.Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.Quantitative microarray profiling of DNA-binding molecules Fluorescent probes for nucleic Acid visualization in fixed and live cells.Modulation of NF-κB-dependent gene transcription using programmable DNA minor groove binders Enhancing the cellular uptake of Py-Im polyamides through next-generation aryl turns.Tumor Repression of VCaP Xenografts by a Pyrrole-Imidazole Polyamide.Characterization and solubilization of pyrrole-imidazole polyamide aggregates Alpha-diaminobutyric acid-linked hairpin polyamides.Single-dose pharmacokinetic and toxicity analysis of pyrrole-imidazole polyamides in mice.Gene expression changes in a tumor xenograft by a pyrrole-imidazole polyamide.Small molecules targeting histone H4 as potential therapeutics for chronic myelogenous leukemia.Direct inhibition of the DNA-binding activity of POU transcription factors Pit-1 and Brn-3 by selective binding of a phenyl-furan-benzimidazole dication Targeting a DNA binding motif of the EVI1 protein by a pyrrole-imidazole polyamide.Activity of a Py-Im polyamide targeted to the estrogen response element.In vivo imaging of pyrrole-imidazole polyamides with positron emission tomography.Cyclic pyrrole-imidazole polyamides targeted to the androgen response element.Solution-phase synthesis of pyrrole-imidazole polyamides Animal toxicity of hairpin pyrrole-imidazole polyamides varies with the turn unit.Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies Oligomerization route to Py-Im polyamide macrocycles.Repression of DNA-binding dependent glucocorticoid receptor-mediated gene expression Small-molecule regulators that mimic transcription factors Approaches to target the genome and its epigenome in cancer.Development of a molecule-recognized promoter DNA sequence for inhibition of HER2 expression.

P2860

Q24669875-C3A5FD78-B5B4-4FED-A332-F3FCADB5B414 Q27656940-BBF49EE1-F1F7-47B5-ACD5-154C6D375C0A Q27664249-2F10018C-0753-4FE4-9E21-99C2487ED9AC Q33286173-C1E5AF4E-DD77-4DED-A1D0-BCFA4792C771 Q33331950-B2A62253-28CE-4E87-8BA9-934D1689BCDC Q33340423-DCC70725-7079-498E-8552-936A1BFD2E4D Q33474085-1093F877-8BEC-42A2-B42B-7F4CE0FBAFCA Q33477522-E4D1E070-EA73-42E9-9130-F449F1ECBDBF Q33607000-DAFB8EBC-D0A3-42F9-AB0B-933CDC416EFA Q33717554-9D492654-0469-403F-9425-8F56E92AFEE8 Q33931195-0C16A440-6A39-481D-99F0-CDF5A8DFF6B1 Q34053649-96633892-F822-4AAD-B326-92210E1E26BA Q34253203-CBAF3E07-6AD0-43EF-9EE4-AAEEB4B2951E Q34302815-27AE0A55-F110-439E-BE14-821DC487AA94 Q34338685-3E33D718-EB54-4EC2-A08C-DEFC836869D3 Q34381076-38C4945E-23DA-4379-990D-1555AE490415 Q34697484-AE42A4CC-D2A0-4431-9BDF-E78881EBFA77 Q34732038-8C4FB038-3379-4110-9DD7-01779359FEBA Q35066396-E59BB4D5-7739-4BF6-8901-CE2FE9CF0992 Q35709298-B9617931-0975-4297-941D-91D1A41DC999 Q35823735-08A6E8DD-A53C-43F2-B37A-FF951B02F6AB Q35842218-F4704609-91F5-466C-8E1E-5E55951459C9 Q36031605-9702033F-68B4-45AE-9623-6777D0C421C7 Q36275137-9B5CE771-C149-49E2-A092-11B235EB440F Q36275422-CADE0D97-45D5-4061-9BE2-9524149F5B8F Q36342812-ABB77F80-9E01-42A6-A416-A00E75ABF2CD Q36647759-3BF3FC47-EC2B-4619-B4EB-3FA2DDD98459 Q36715552-BDA56135-8478-4BF0-9CAC-C6EE769756FA Q36749396-BC14CA41-5EF0-40DE-8161-12DA5217A748 Q36836841-FE7027C6-7385-4ED9-81CB-ED44F852324D Q36861667-C9C9E297-7236-44D6-AE2F-AA1BDED53F08 Q37209293-D79BC241-D8E4-4406-8858-F1C4AED8BD51 Q37209301-A314660F-B30F-4576-8B12-7C201724F9D4 Q37210876-A17DD69F-E3E0-4B1A-828C-6BCACB2648A8 Q37268036-63B5794A-8E61-4296-9E52-85372D34E6DC Q37329318-1C517CE7-35F7-4962-BDE2-65FED2A3B5B8 Q37348402-3317B73C-85C2-475B-8840-36427D6853F8 Q37784071-7CA9CFF8-6913-40E0-927E-D4B79797CAC8 Q37855866-26DF6EBB-8817-480A-A675-4818E69104CC Q39851156-E13DC2AC-D938-40F1-ABC9-3EEE3DFDF8A2

P2860

Improved nuclear localization of DNA-binding polyamides.

http://www.wikidata.org/entity/Q33266897

description

2006 nî lūn-bûn

@nan

2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2006年の論文

@ja

2006年論文

@yue

2006年論文

@zh-hant

2006年論文

@zh-hk

2006年論文

@zh-mo

2006年論文

@zh-tw

2006年论文

@wuu

name

Improved nuclear localization of DNA-binding polyamides.

@ast

Improved nuclear localization of DNA-binding polyamides.

@en

type

label

Improved nuclear localization of DNA-binding polyamides.

@ast

Improved nuclear localization of DNA-binding polyamides.

@en

prefLabel

Improved nuclear localization of DNA-binding polyamides.

@ast

Improved nuclear localization of DNA-binding polyamides.

@en

P1433

Q33266897-4CE1F2A6-A2CA-43C4-BEC3-1B2D6AEB3FC4

P1476

Q33266897-CC14F813-172D-427D-A723-591B1EA3FAD2

P2093

Q33266897-2B16FC01-1D57-4360-BA35-AE9D372EDE3B

Q33266897-7847097A-AC7A-40E0-8092-D77FA55AD90E

Q33266897-DA2220FD-62CF-4048-8FDE-6FA8F42742F5

P2860

Q33266897-05644D60-E310-463A-BF65-40E76003A279

Q33266897-13CD82A0-54F3-4FDF-8FA3-860E42F0DCB6

Q33266897-157BB497-D76C-4680-9D93-F0F1B4A654C6

Q33266897-2952591A-81C9-4BCB-9348-112E29B760F4

Q33266897-32FCB280-1216-47B1-AC4D-84A832DD3335

Q33266897-35FE5AA4-6E0B-4095-B11E-E10F1D9B9D51

Q33266897-3C62FD03-309C-4E36-955B-9AFF573481CB

Q33266897-3CAFAD12-5E24-468E-ADC6-86DFBAA0D826

Q33266897-494C48B2-323D-4331-8278-8A77F6D6268F

Q33266897-549F98BA-79CE-40E6-B9E4-00AB2CCE178B

P304

Q33266897-F93EDEE2-A20F-41AC-9804-4A1F46F3F6B9

P31

Q33266897-DFD30006-D283-4C8F-92CB-8275CF7C8E0A

P356

Q33266897-D4EA268E-B23F-433D-AE27-FB8C0BF67241

P407

Q33266897-EB5CA153-D5DD-4AB7-9B69-61BE8BC66288

P433

Q33266897-60404134-E271-43F0-9FC6-9D0E8AA1D499

P478

Q33266897-D993B3AC-2D0B-47B4-90FB-D8CA58DD4F39

P50

Q33266897-8CF0E5F9-878E-4C0B-82D4-D75A5E2A4265

P577

Q33266897-C35D580C-02E6-456F-A2D0-166DFE1CC47B

P5875

Q33266897-4DD3BA5D-2C66-48FE-BA7E-083119629C32

P698

Q33266897-1C8952B5-1FB3-4ED7-9DD6-E73667CD4AFB

P932

Q33266897-1E1DE90C-9E79-477A-A2A7-91298996A5DA

P356

P1433

Nucleic Acids Research

P1476

Improved nuclear localization of DNA-binding polyamides.

@en

P2093

Claire S Jacobs

http://www.w3.org/2001/XMLSchema#string

Michelle E Farkas

http://www.w3.org/2001/XMLSchema#string

Nicholas G Nickols

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structures of nucleosome core particles in complex with minor groove DNA-binding ligands

Structural basis for G.C recognition in the DNA minor groove

Recognition of the DNA minor groove by pyrrole-imidazole polyamides

Molecular recognition of DNA by small molecules

Regulation of gene expression by small molecules

Recognition of the four Watson-Crick base pairs in the DNA minor groove by synthetic ligands

Inhibition of RNA polymerase II transcription in human cells by synthetic DNA-binding ligands

Cellular uptake of N-methylpyrrole/N-methylimidazole polyamide-dye conjugates.

Nuclear localization of pyrrole-imidazole polyamide-fluorescein conjugates in cell culture.

Echinomycin, a small-molecule inhibitor of hypoxia-inducible factor-1 DNA-binding activity.

P304

363-370

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1093/NAR/GKL1042

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

35

http://www.w3.org/2001/XMLSchema#string

P50

P577

2006-12-14T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6623700

http://www.w3.org/2001/XMLSchema#string

P698

17175539

http://www.w3.org/2001/XMLSchema#string

P932

1802595

http://www.w3.org/2001/XMLSchema#string