The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled.
about
Structural position correlation analysis (SPCA) for protein familyIntegration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2.Correlation analysis for protein evolutionary family based on amino acid position mutations and application in PDZ domain.c-Myc and transforming growth factor α enhance the development of hepatic lesions due to mutant β-catenin in transgenic miceModulation of the ligand-independent traffic of Notch by Axin and Apc contributes to the activation of Armadillo in Drosophila.Bi-factor analysis based on noise-reduction (BIFANR): a new algorithm for detecting coevolving amino acid sites in proteins.Canoe binds RanGTP to promote Pins(TPR)/Mud-mediated spindle orientation.Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo.Formin-mediated actin polymerization cooperates with Mushroom body defect (Mud)-Dynein during Frizzled-Dishevelled spindle orientation.The exon junction complex regulates the splicing of cell polarity gene dlg1 to control Wingless signaling in development.The Drosophila afadin homologue Canoe regulates linkage of the actin cytoskeleton to adherens junctions during apical constriction.Cardiac gene regulatory networks in Drosophila.Rap1 maintains adhesion between cells to affect Egfr signaling and planar cell polarity in DrosophilaLoss of polarity protein AF6 promotes pancreatic cancer metastasis by inducing Snail expression.Loss of AF6/afadin, a marker of poor outcome in breast cancer, induces cell migration, invasiveness and tumor growth.Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.Notch signaling mediates granulocyte-macrophage colony-stimulating factor priming-induced transendothelial migration of human eosinophils.ZO-1 regulates Erk, Smad1/5/8, Smad2, and RhoA activities to modulate self-renewal and differentiation of mouse embryonic stem cells.Synergism between canoe and scribble mutations causes tumor-like overgrowth via Ras activation in neural stem cells and epithelia.The interaction of Jagged-1 cytoplasmic tail with afadin PDZ domain is local, folding-independent, and tuned by phosphorylation.CLDN2 inhibits the metastasis of osteosarcoma cells via down-regulating the afadin/ERK signaling pathway
P2860
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P2860
The PDZ protein Canoe/AF-6 links Ras-MAPK, Notch and Wingless/Wnt signaling pathways by directly interacting with Ras, Notch and Dishevelled.
description
2006 nî lūn-bûn
@nan
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@ast
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@en
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@nl
type
label
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@ast
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@en
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@nl
prefLabel
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@ast
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@en
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@nl
P2093
P2860
P1433
P1476
The PDZ protein Canoe/AF-6 lin ...... th Ras, Notch and Dishevelled.
@en
P2093
Ana Carmena
Mary Baylies
Stephan Speicher
P2860
P356
10.1371/JOURNAL.PONE.0000066
P407
P577
2006-12-20T00:00:00Z