A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
about
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG islandmiRNA gene promoters are frequent targets of aberrant DNA methylation in human breast cancerEFS shows biallelic methylation in uveal melanoma with poor prognosis as well as tissue-specific methylationMutator pathways unleashed by epigenetic silencing in human cancerOxidative damage targets complexes containing DNA methyltransferases, SIRT1, and polycomb members to promoter CpG IslandsDACT3 is an epigenetic regulator of Wnt/beta-catenin signaling in colorectal cancer and is a therapeutic target of histone modificationsCpG island methylation in colorectal cancer: past, present and futureEpigenetics of colorectal cancerEpigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthMutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomasA decade of exploring the cancer epigenome - biological and translational implicationsCD133: to be or not to be, is this the real question?DNA methylation screening identifies driver epigenetic events of cancer cell survivalA histone demethylase is necessary for regeneration in zebrafishSALL3 interacts with DNMT3A and shows the ability to inhibit CpG island methylation in hepatocellular carcinomaEarly-life exposures to infectious agents and later cancer developmentPoised chromatin in the mammalian germ lineA double take on bivalent promotersThe cancer epigenome: its origins, contributions to tumorigenesis, and translational implicationsEpigenomics of cancer - emerging new conceptsRegulation of ovarian cancer stem cells or tumor-initiating cellsHistone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionAltered histone modifications in gliomasDNA-methylome analysis of mouse intestinal adenoma identifies a tumour-specific signature that is partly conserved in human colon cancerBreast cancer epigenetics: from DNA methylation to microRNAsMethylation analyses in liquid biopsyStem cells and colorectal carcinogenesisMolecular pathogenesis of sporadic colorectal cancersGenome-wide epigenomic profiling for biomarker discoveryEpigenetic regulation of the intestinal epitheliumOrphan CpG islands identify numerous conserved promoters in the mammalian genomeDifferences in DNA methylation signatures reveal multiple pathways of progression from adenoma to colorectal cancerCpG islands and the regulation of transcriptionAging-Induced Stem Cell Mutations as Drivers for Disease and CancerRecurrent epimutations activate gene body promoters in primary glioblastomaDNA methylation analysis of chromosome 21 gene promoters at single base pair and single allele resolutionA network of cancer genes with co-occurring and anti-co-occurring mutationsThe dynamics and prognostic potential of DNA methylation changes at stem cell gene loci in women's cancerDnmt3b promotes tumorigenesis in vivo by gene-specific de novo methylation and transcriptional silencingRole of DNA methylation and epigenetic silencing of HAND2 in endometrial cancer development
P2860
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P2860
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
A stem cell-like chromatin pat ...... lation and heritable silencing
@ast
A stem cell-like chromatin pat ...... lation and heritable silencing
@en
A stem cell-like chromatin pat ...... ation and heritable silencing.
@nl
type
label
A stem cell-like chromatin pat ...... lation and heritable silencing
@ast
A stem cell-like chromatin pat ...... lation and heritable silencing
@en
A stem cell-like chromatin pat ...... ation and heritable silencing.
@nl
prefLabel
A stem cell-like chromatin pat ...... lation and heritable silencing
@ast
A stem cell-like chromatin pat ...... lation and heritable silencing
@en
A stem cell-like chromatin pat ...... ation and heritable silencing.
@nl
P2093
P2860
P356
P1433
P1476
A stem cell-like chromatin pat ...... lation and heritable silencing
@en
P2093
D Neil Watkins
David M Berman
Helai P Mohammad
James G Herman
Joyce E Ohm
Kelly M McGarvey
Kevin Pruitt
Kornel E Schuebel
Leslie Cope
Saul J Sharkis
P2860
P2888
P304
P356
10.1038/NG1972
P407
P577
2007-01-09T00:00:00Z