Sp1 is essential for p16 expression in human diploid fibroblasts during senescence. - Wikidata - awgldk - TriplyDB

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

http://www.wikidata.org/entity/Q33269339

about

The role of SIRT6 protein in aging and reprogramming of human induced pluripotent stem cells C-terminal in Sp1-like artificial zinc-finger proteins plays crucial roles in determining their DNA binding affinity.Polymorphisms in promoter sequences of MDM2, p53, and p16 genes in normal Japanese individuals.Identification of poly(ADP-ribose) polymerase-1 as a cell cycle regulator through modulating Sp1 mediated transcription in human hepatoma cells.Sal-like protein 2 upregulates p16 expression through a proximal promoter element.Possible down regulation of the p16 gene promoter in individuals with hepatocellular carcinoma.CLCA2 as a p53-inducible senescence mediator.Epigenetic silencing of the p16(INK4a) tumor suppressor is associated with loss of CTCF binding and a chromatin boundary.p16(Ink4a) overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors.Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer.Sp1 and the 'hallmarks of cancer'.Construction of a computable network model for DNA damage, autophagy, cell death, and senescence.Promoter cloning and characterization of the human programmed cell death protein 4 (pdcd4) gene: evidence for ZBP-89 and Sp-binding motifs as essential Pdcd4 regulators.Senescence as a novel mechanism involved in β-adrenergic receptor mediated cardiac hypertrophy.Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells.B-MYB delays cell aging by repressing p16 (INK4α) transcription.Alterations in the Sp1 binding and Fmr-1 gene expression in the cortex of the brain during maturation and aging of mouse.Downregulation of the Apelinergic Axis Accelerates Aging, whereas Its Systemic Restoration Improves the Mammalian Healthspan.Transcription factor Sp1 prevents TRF2(ΔBΔM)-induced premature senescence in human diploid fibroblasts.Sumoylation-deficient Prdx6 repairs aberrant Sumoylation-mediated Sp1 dysregulation-dependent Prdx6 repression and cell injury in aging and oxidative stress

P2860

Q30540850-EF69A8FD-FA08-41BB-9C83-B332F31E0B94 Q34449740-02AC2794-A018-4E70-ADBD-6ECF552FC17A Q34562906-07212C01-3C48-40D8-BFDD-1EC4D4F0E664 Q35075466-00549BFA-A6D5-42D2-8917-D031C24E4175 Q35223877-128C6CC9-EF8A-4C97-84EB-DD657B42FE4B Q35603750-56624270-8302-499B-9097-C2D164039D74 Q35836043-CCAEACDD-9E07-4004-A872-FF0F7695B6DE Q37297042-FBDB144A-EACD-4E66-9A3C-C65FCAC54277 Q37836381-29447D6A-1622-4B9F-BCF6-44185395B64D Q37880852-BC862053-887C-47F4-B235-B75CCC371BB1 Q38267908-1C9DA72B-80FD-4763-A327-D5F498586A66 Q38454300-D1374C85-61BE-40F7-8700-4B6CA7F11856 Q39438243-EA4DBA80-0387-4972-9931-63F785FCF7F0 Q41257641-84DFE5F2-2339-4677-A66E-5824E256BE74 Q42552522-29EA26A8-E4B0-49AC-8E2E-959BC1DE5D7A Q45909407-8D3E5E93-CB63-4086-9BD0-C2278581CEDB Q46613683-DB7AB99F-B2FE-4D5B-B8FF-C230C0590C8D Q50104995-185EF3B4-86CB-4B8A-BACF-FB58F54E18C9 Q51501058-F74CC5D9-8825-4339-BF6F-8060CB296CB1 Q58744776-2CCCC7EA-4BFE-4392-AC69-04FB110BB440

P2860

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

http://www.wikidata.org/entity/Q33269339

description

2007 nî lūn-bûn

@nan

2007 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հունվարին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@ast

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@en

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@nl

type

label

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@ast

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@en

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@nl

prefLabel

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@ast

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@en

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@nl

P1433

Q33269339-644B5BA4-B560-4946-9822-0D5D00475A35

P1476

Q33269339-B5DF4F3B-EAFF-4478-8DD1-C79B75ACB6E7

P2093

Q33269339-3ABE1355-C056-47AD-BBD9-2820CDCF5AD2

Q33269339-747A4CAD-BCF4-4828-B8C8-A598C7CE40B2

Q33269339-866B1ED7-2983-42FE-A4BC-3563A1EA049E

Q33269339-8E1F8963-97F3-48F8-919E-726C2301D24C

Q33269339-AEB5D87F-9CA6-4B79-B076-A623E3D447F3

Q33269339-B41C144C-809D-42EB-A33A-CD4F4129406B

Q33269339-DA5BC49D-AF7B-4307-B167-A0AD9B20F407

P2860

Q33269339-069D96AF-A30C-4152-A2D9-B8392C4E0F4E

Q33269339-09764B4B-1EA1-45F4-8155-6574FE4833E1

Q33269339-2407C5DE-5382-4510-A476-6EC42C15AEB2

Q33269339-297109D8-0AD6-4174-8060-33A354151755

Q33269339-30C5DF2F-CEA6-4621-85E8-85D6EEEEBA90

Q33269339-3A558C21-BFF1-4D0D-9BE4-2AB100F8F28D

Q33269339-3F97CBCE-CA3F-4C5F-AF73-9DD4A454ACB3

Q33269339-4042AC0A-8F53-4FBE-9775-DBEED5A5074E

Q33269339-440622FA-E4D8-4932-B52C-26A4DD4331E0

Q33269339-4B8FE7D2-EE3D-4168-9940-27B2AD6DA103

P304

Q33269339-097A9AE7-4506-4492-B0DB-DCE2CA74DE26

P31

Q33269339-A2B66B95-FAB2-43E3-9631-FB3062E366C5

P356

Q33269339-71937025-1022-4164-A9C3-DFE5AF8B8443

P407

Q33269339-06B616DE-31DE-4024-9C94-7CD8661FAF34

P433

Q33269339-C9D75045-CA5E-4358-B4EF-B377B22EA393

P478

Q33269339-21AA579E-D74C-49E5-9B4A-7DE0F5888C4D

P577

Q33269339-B1199CE8-560D-4E1A-ABB7-2D6F9813FF57

P5875

Q33269339-9C9878A4-B2E2-430E-93F2-D937FC5D33D8

P698

Q33269339-2BC48284-09BD-43FA-8CD1-D2605DC868A0

P932

Q33269339-AEE06C3C-F9E1-4453-A11A-A3F064080C0A

P356

JOURNAL.PONE.0000164

P1433

P1476

Sp1 is essential for p16 expression in human diploid fibroblasts during senescence.

@en

P2093

Junfeng Wu

http://www.w3.org/2001/XMLSchema#string

Lixiang Xue

http://www.w3.org/2001/XMLSchema#string

Mo Weng

http://www.w3.org/2001/XMLSchema#string

Tanjun Tong

http://www.w3.org/2001/XMLSchema#string

Wengong Wang

http://www.w3.org/2001/XMLSchema#string

Ying Sun

http://www.w3.org/2001/XMLSchema#string

Zongyu Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

Functional interactions between Sp1 or Sp3 and the helicase-like transcription factor mediate basal expression from the human plasminogen activator inhibitor-1 gene

PML regulates p53 acetylation and premature senescence induced by oncogenic Ras

Regulation of cellular senescence and p16(INK4a) expression by Id1 and E47 proteins in human diploid fibroblast

O-glycosylation of eukaryotic transcription factors: implications for mechanisms of transcriptional regulation

Superoxide dismutase 1 knock-down induces senescence in human fibroblasts

Control of the replicative life span of human fibroblasts by p16 and the polycomb protein Bmi-1

O glycosylation of an Sp1-derived peptide blocks known Sp1 protein interactions

Atmospheric carbon dioxide concentrations over the past 60 million years

THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS

Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence

P304

e164

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1371/JOURNAL.PONE.0000164

http://www.w3.org/2001/XMLSchema#string

P407

P433

1

http://www.w3.org/2001/XMLSchema#string

P478

2

http://www.w3.org/2001/XMLSchema#string

P577

2007-01-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

6576288

http://www.w3.org/2001/XMLSchema#string

P698

17225865

http://www.w3.org/2001/XMLSchema#string

P932

1764714

http://www.w3.org/2001/XMLSchema#string