about
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) ProdrugsTrans,trans,trans-[PtIV(N3)2(OH)2(py)(NH3)]: a light-activated antitumor platinum complex that kills human cancer cells by an apoptosis-independent mechanism.Unusual DNA binding modes for metal anticancer complexes.Photocytotoxic trans-diam(m)ine platinum(IV) diazido complexes more potent than their cis isomers.Photoactivated chemotherapy (PACT): the potential of excited-state d-block metals in medicine.Antitumor carboplatin is more toxic in tumor cells when photoactivated: enhanced DNA binding.Understanding and improving platinum anticancer drugs--phenanthriplatinMixed ligand μ-phenoxo-bridged dinuclear copper(II) complexes with diimine co-ligands: efficient chemical nuclease and protease activities and cytotoxicity.Replacement of a thiourea with an amidine group in a monofunctional platinum-acridine antitumor agent. Effect on DNA interactions, DNA adduct recognition and repair.Mixed ligand copper(II) dicarboxylate complexes: the role of co-ligand hydrophobicity in DNA binding, double-strand DNA cleavage, protein binding and cytotoxicity.Triplet-triplet annihilation upconversion followed by FRET for the red light activation of a photodissociative ruthenium complex in liposomes.Photodynamic killing of cancer cells by a Platinum(II) complex with cyclometallating ligand.A potent cytotoxic photoactivated platinum complexFuture of oncologic photodynamic therapy.Inorganic nanoparticles in cancer therapy.Keys for unlocking photolabile metal-containing cages.Fast and slow versus strong and weak metal-DNA binding: consequences for anti-cancer activity.Quantum dot photosensitizers. Interactions with transition metal centers.Effects of light-activated diazido-PtIV complexes on cancer cells in vitro.Photoactivatable metal complexes: from theory to applications in biotechnology and medicine.Target-selective delivery and activation of platinum-based anticancer agents.Polymeric biomaterials for the delivery of platinum-based anticancer drugs.Exploiting developments in nanotechnology for the preferential delivery of platinum-based anti-cancer agents to tumours: targeting some of the hallmarks of cancer.Platinum complexes as light promoted anticancer agents: a redefined strategy for controlled activation.Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance.Synthesis, X-ray structure and in vitro cytotoxicity studies of Cu(I/II) complexes of thiosemicarbazone: special emphasis on their interactions with DNA.Syntheses and structural investigation of some alkali metal ion-mediated LV(V)O2(-) (L(2-) = tridentate ONO ligands) species: DNA binding, photo-induced DNA cleavage and cytotoxic activities.Water-soluble DNA minor groove binders as potential chemotherapeutic agents: synthesis, characterization, DNA binding and cleavage, antioxidation, cytotoxicity and HSA interactions.Potentially cytotoxic new copper(II) hydrazone complexes: synthesis, crystal structure and biological properties.Studies on the photoactivation of two cytotoxic trans,trans,trans-diazidodiaminodihydroxo-Pt(IV) complexes.Comprehensive Vibrational Spectroscopic Investigation of trans,trans,trans-[Pt(N3)2(OH)2(py)2], a Pt(IV) Diazido Anticancer Prodrug Candidate.Photoinduced reactions of cis,trans,cis-[Pt(IV)(N3)2(OH)2(NH3)2) with 1-methylimidazole.Photoactivation of trans diamine platinum complexes in aqueous solution and effect on reactivity towards nucleotides.Synthesis, characterisation and photochemistry of Pt(IV) pyridyl azido acetato complexes.Controlling Platinum, Ruthenium and Osmium Reactivity for Anticancer Drug Design.Advances in platinum chemotherapeutics.In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent.Anticancer platinum complexes as non-innocent compounds for catalysis in aqueous media.Metal to ligand charge transfer induced DNA photobinding in a Ru(II)-Pt(II) supramolecule using red light in the therapeutic window: a new mechanism for DNA modification.Spontaneous translocation of antitumor oxaliplatin, its enantiomeric analogue, and Cisplatin from one strand to another in double-helical DNA.
P2860
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P2860
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Photoactivatable platinum complexes.
@ast
Photoactivatable platinum complexes.
@en
Photoactivatable platinum complexes.
@nl
type
label
Photoactivatable platinum complexes.
@ast
Photoactivatable platinum complexes.
@en
Photoactivatable platinum complexes.
@nl
prefLabel
Photoactivatable platinum complexes.
@ast
Photoactivatable platinum complexes.
@en
Photoactivatable platinum complexes.
@nl
P2093
P1476
Photoactivatable platinum complexes.
@en
P2093
Fiona S Mackay
Patrick J Bednarski
Peter J Sadler
P356
10.2174/187152007779314053
P577
2007-01-01T00:00:00Z