TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis.
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TREM2 Variants in Alzheimer's DiseaseIdentification of soluble TREM-2 in the cerebrospinal fluid and its association with multiple sclerosis and CNS inflammationGenetics ignite focus on microglial inflammation in Alzheimer's diseaseTREM2 in CNS homeostasis and neurodegenerative diseaseThe triggering receptor expressed on myeloid cells (TREM) in inflammatory bowel disease pathogenesisRole of microglia in CNS autoimmunityImmune modulation of stem cells and regenerationMicroglia recapitulate a hematopoietic master regulator network in the aging human frontal cortexFunctional involvement of γ-secretase in signaling of the triggering receptor expressed on myeloid cells-2 (TREM2).Monocyte Trafficking, Engraftment, and Delivery of Nanoparticles and an Exogenous Gene into the Acutely Inflamed Brain Tissue - Evaluations on Monocyte-Based Delivery System for the Central Nervous SystemGenomic Modifiers of Natural Killer Cells, Immune Responsiveness and Lymphoid Tissue Remodeling Together Increase Host Resistance to Viral InfectionInefficient clearance of myelin debris by microglia impairs remyelinating processesTemporal-logic analysis of microglial phenotypic conversion with exposure to amyloid-β.Tracking the transcriptional host response from the acute to the regenerative phase of experimental pneumococcal meningitis.Alterations in CD200-CD200R1 System during EAE Already Manifest at Presymptomatic Stages.The linker for activation of B cells (LAB)/non-T cell activation linker (NTAL) regulates triggering receptor expressed on myeloid cells (TREM)-2 signaling and macrophage inflammatory responses independently of the linker for activation of T cells.TREM2 protects against cerebral ischemia/reperfusion injuryIntegrative DNA, RNA, and protein evidence connects TREML4 to coronary artery calcificationDAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2Dual induction of TREM2 and tolerance-related transcript, Tmem176b, in amyloid transgenic mice: implications for vaccine-based therapies for Alzheimer's disease.Microglial activation mediates host neuronal survival induced by neural stem cells.A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective functionCoding variants in TREM2 increase risk for Alzheimer's diseaseMicroglia: unique and common features with other tissue macrophages.The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis.Upregulation of TREM2 ameliorates neuropathology and rescues spatial cognitive impairment in a transgenic mouse model of Alzheimer's diseaseAttenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke.Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease.In vitro and in vivo models of cerebral ischemia show discrepancy in therapeutic effects of M2 macrophagesDevelopment of a culture system to induce microglia-like cells from haematopoietic cells.The role of microglia and myeloid immune cells in acute cerebral ischemia.Differential modulation of TREM2 protein during postnatal brain development in mice.Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.IFNβ secreted by microglia mediates clearance of myelin debris in CNS autoimmunityThe critical role of antigen-presentation-induced cytokine crosstalk in the central nervous system in multiple sclerosis and experimental autoimmune encephalomyelitis.Oral administration of the KATP channel opener diazoxide ameliorates disease progression in a murine model of multiple sclerosis.TREM-2 promotes macrophage survival and lung disease after respiratory viral infectionTREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal CorticesThe Receptor CMRF35-Like Molecule-1 (CLM-1) Enhances the Production of LPS-Induced Pro-Inflammatory Mediators during Microglial Activation.The expanding roles of ITAM adapters FcRgamma and DAP12 in myeloid cells.
P2860
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P2860
TREM2-transduced myeloid precursors mediate nervous tissue debris clearance and facilitate recovery in an animal model of multiple sclerosis.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@ast
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@en
type
label
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@ast
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@en
prefLabel
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@ast
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@en
P2093
P2860
P1433
P1476
TREM2-transduced myeloid precu ...... l model of multiple sclerosis.
@en
P2093
Kazuya Takahashi
Marco Prinz
Olga Chechneva
P2860
P356
10.1371/JOURNAL.PMED.0040124
P407
P577
2007-04-01T00:00:00Z