Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
about
Towards a unifying, systems biology understanding of large-scale cellular death and destruction caused by poorly liganded iron: Parkinson's, Huntington's, Alzheimer's, prions, bactericides, chemical toxicology and others as examplesMolecular biology of lung cancer: clinical implicationsGenomic screening with RNAi: results and challengesStatistical methods for analysis of high-throughput RNA interference screensA genome-wide RNAi screen for Wnt/beta-catenin pathway components identifies unexpected roles for TCF transcription factors in cancerSynthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancerEctopic Expression of Testis Germ Cell Proteins in Cancer and Its Potential Role in Genomic InstabilityFrom Mice to Men and Back: An Assessment of Preclinical Model Systems for the Study of Lung CancersCancer Cell Line Panels Empower Genomics-Based Discovery of Precision Cancer MedicineAdvances in CRISPR-Cas9 genome engineering: lessons learned from RNA interferenceUnravelling the molecular complexity of GPCR-mediated EGFR transactivation using functional genomics approachesCancer's Achilles' Heel: Apoptosis and Necroptosis to the RescueNarrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypesThe p53 circuit boardCyclopamine tartrate, an inhibitor of Hedgehog signaling, strongly interferes with mitochondrial function and suppresses aerobic respiration in lung cancer cellsRhoJ regulates melanoma chemoresistance by suppressing pathways that sense DNA damageIntegrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line setPre-clinical drug prioritization via prognosis-guided genetic interaction networksAn intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitorHost modulators of H1N1 cytopathogenicityTDP-43 identified from a genome wide RNAi screen for SOD1 regulatorsAn RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancerVirtual and biophysical screening targeting the γ-tubulin complex--a new target for the inhibition of microtubule nucleationTarget inhibition networks: predicting selective combinations of druggable targets to block cancer survival pathwaysConnectivity Homology Enables Inter-Species Network Models of Synthetic LethalityThe Power Decoder Simulator for the Evaluation of Pooled shRNA Screen PerformanceA genome-scale screen reveals context-dependent ovarian cancer sensitivity to miRNA overexpressionmiR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancersSystems-level cancer gene identification from protein interaction network topology applied to melanogenesis-related functional genomics dataCancer: fundamentals behind pH targeting and the double-edged approachComprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancerTopoisomerase levels determine chemotherapy responsein vitroandin vivoMultiple cancer testis antigens function to support tumor cell mitotic fidelity.Identification of druggable targets for radiation mitigation using a small interfering RNA screening assayIdentification of chemosensitivity nodes for vinblastine through small interfering RNA high-throughput screens.Spindle poisons and cell fate: a tale of two pathways.SbacHTS: spatial background noise correction for high-throughput RNAi screening.Autonomous screening of C. elegans identifies genes implicated in synaptogenesisNakiterpiosin targets tubulin and triggers mitotic catastrophe in human cancer cellsAnalysis of high-throughput RNAi screening data in identifying genes mediating sensitivity to chemotherapeutic drugs: statistical approaches and perspectives
P2860
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P2860
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
description
2007 nî lūn-bûn
@nan
2007 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@ast
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@en
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@nl
type
label
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@ast
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@en
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@nl
prefLabel
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@ast
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@en
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@nl
P2093
P356
P1433
P1476
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
@en
P2093
Angelique W Whitehurst
Brian O Bodemann
Carolyn Michnoff
Deborah Ferguson
Jessica Cardenas
John D Minna
Luc Girard
Michael A White
Michael Peyton
Weihua Hao
P2888
P304
P356
10.1038/NATURE05697
P407
P50
P577
2007-04-01T00:00:00Z
P5875
P6179
1009958699