MUC16 is produced in tracheal surface epithelium and submucosal glands and is present in secretions from normal human airway and cultured bronchial epithelial cells.
about
Role of epithelial mucins during airway infectionDeciphering the molecular nature of ovarian cancer biomarker CA125Airway Gland Structure and FunctionSPDEF is required for mouse pulmonary goblet cell differentiation and regulates a network of genes associated with mucus productionMUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouseCA125/MUC16 is dispensable for mouse development and reproductionMUC16 (CA125): tumor biomarker to cancer therapy, a work in progressAirway mucus function and dysfunction.Comparison of the transmembrane mucins MUC1 and MUC16 in epithelial barrier function.Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes.HN125: A Novel Immunoadhesin Targeting MUC16 with Potential for Cancer TherapyHyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.Cell surface marker profiling of human tracheal basal cells reveals distinct subpopulations, identifies MST1/MSP as a mitogenic signal, and identifies new biomarkers for lung squamous cell carcinomas.Cystic fibrosis and the relationship between mucin and chloride secretion by cultures of human airway gland mucous cells.Transmembrane mucins as novel therapeutic targetsSOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis.Phorbol 12-Myristate 13-Acetate Induces MUC16 Expression via PKCδ and p38 in Human Airway Epithelial Cells.Highly pathogenic avian influenza H5N1 viruses elicit an attenuated type i interferon response in polarized human bronchial epithelial cells.Molecular organization of the mucins and glycocalyx underlying mucus transport over mucosal surfaces of the airwaysTumor necrosis factor-α and interferon-γ stimulate MUC16 (CA125) expression in breast, endometrial and ovarian cancers through NFκB.Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.The Spl Serine Proteases Modulate Staphylococcus aureus Protein Production and Virulence in a Rabbit Model of Pneumonia.C-terminus of MUC16 activates Wnt signaling pathway through its interaction with β-catenin to promote tumorigenesis and metastasis.IL-1β induction of MUC5AC gene expression is mediated by CREB and NF-κB and repressed by dexamethasone.Correlates of circulating ovarian cancer early detection markers and their contribution to discrimination of early detection models: results from the EPIC cohortTumour biomarkers in heart failure: is there a role for CA-125?Cellular and molecular biology of airway mucins.Generation and characterization of a monoclonal antibody to the cytoplasmic tail of MUC16.Directed differentiation of human pluripotent stem cells into mature airway epithelia expressing functional CFTR protein.Carboxyl-terminal domain of MUC16 imparts tumorigenic and metastatic functions through nuclear translocation of JAK2 to pancreatic cancer cells.Suppression of Toll-like receptor-mediated innate immune responses at the ocular surface by the membrane-associated mucins MUC1 and MUC16Biosynthesis of the polymeric gel-forming mucin MUC5BMembrane proximal ectodomain cleavage of MUC16 occurs in the acidifying Golgi/post-Golgi compartments.Innate immune defense in the inner ear - mucines are expressed by the human endolymphatic sac.Development and characterization of carboxy-terminus specific monoclonal antibodies for understanding MUC16 cleavage in human ovarian cancer.Momelotinib decreased cancer stem cell associated tumor burden and prolonged disease-free remission period in a mouse model of human ovarian cancer.
P2860
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P2860
MUC16 is produced in tracheal surface epithelium and submucosal glands and is present in secretions from normal human airway and cultured bronchial epithelial cells.
description
2007 nî lūn-bûn
@nan
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@ast
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@en
type
label
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@ast
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@en
prefLabel
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@ast
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@en
P2093
P1476
MUC16 is produced in tracheal ...... ed bronchial epithelial cells.
@en
P2093
Ingemar Carlstedt
Naila Svitacheva
Sara Kirkham
P304
P356
10.1016/J.BIOCEL.2007.05.013
P577
2007-05-25T00:00:00Z