The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex.
about
Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cellsThe kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes.A WASp-VASP complex regulates actin polymerization at the plasma membrane.Involvement of the Arp2/3 complex and Scar2 in Golgi polarity in scratch wound modelsPolyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorptionEssential function of dynamin in the invasive properties and actin architecture of v-Src induced podosomes/invadosomesImmunological responses and actin dynamics in macrophages are controlled by N-cofilin but are independent from ADFMetalloproteinase MT1-MMP islets act as memory devices for podosome reemergenceCharacterization of two classes of small molecule inhibitors of Arp2/3 complexControl of polarized assembly of actin filaments in cell motilityThe acidic regions of WASp and N-WASP can synergize with CDC42Hs and Rac1 to induce filopodia and lamellipodiaAdhesion structures and their cytoskeleton-membrane interactions at podosomes of osteoclasts in cultureWiskott-Aldrich syndrome protein and the cytoskeletal dynamics of dendritic cellsDramatic inhibition of osteoclast sealing ring formation and bone resorption in vitro by a WASP-peptide containing pTyr294 amino acidThe BAR Domain Superfamily Proteins from Subcellular Structures to Human DiseasesRegulation of the formation and trafficking of vesicles from Golgi by PCH family proteins during chemotaxisSequential signals toward podosome formation in NIH-src cells.Induction of Macrophage Function in Human THP-1 Cells Is Associated with Rewiring of MAPK Signaling and Activation of MAP3K7 (TAK1) Protein KinaseThe formin FRL1 (FMNL1) is an essential component of macrophage podosomes.Supervillin couples myosin-dependent contractility to podosomes and enables their turnoverProcessive acceleration of actin barbed-end assembly by N-WASP.Macrophages of patients with X-linked thrombocytopenia display an attenuated Wiskott-Aldrich syndrome phenotype.Wiskott-Aldrich syndrome: a comprehensive review.A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies.The genetic profiling of preferentially expressed genes in murine splenic CD8α+ dendritic cells.Podosomes in adhesion, migration, mechanosensing and matrix remodeling.WASp in immune-system organization and function.The Wiskott-Aldrich syndrome protein: forging the link between actin and cell activation.Leukocyte uropod formation and membrane/cytoskeleton linkage in immune interactions.Membrane lipids in invadopodia and podosomes: key structures for cancer invasion and metastasisCD44 and beta3 integrin organize two functionally distinct actin-based domains in osteoclastsWASP and WIP regulate podosomes in migrating leukocytes.Actin machinery and mechanosensitivity in invadopodia, podosomes and focal adhesions.Podosomal proteins as causes of human syndromes: a role in craniofacial development?Signaling networks regulating leukocyte podosome dynamics and function.Regulation of tyrosine phosphorylation in macrophage phagocytosis and chemotaxis.Mechanistic insights into the regulation of circular dorsal ruffle formation.Podosomes in space: macrophage migration and matrix degradation in 2D and 3D settings.Tools of the trade: podosomes as multipurpose organelles of monocytic cells.Global treadmilling coordinates actin turnover and controls the size of actin networks.
P2860
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P2860
The polarization defect of Wiskott-Aldrich syndrome macrophages is linked to dislocalization of the Arp2/3 complex.
description
2000 nî lūn-bûn
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2000 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հուլիսին հրատարակված գիտական հոդված
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2000年の論文
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2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@ast
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@en
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@nl
type
label
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@ast
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@en
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@nl
prefLabel
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@ast
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@en
The polarization defect of Wis ...... ization of the Arp2/3 complex.
@nl
P2093
P1476
The polarization defect of Wis ...... lization of the Arp2/3 complex
@en
P2093
M Aepfelbacher
U Pannicke
P304
P356
10.4049/JIMMUNOL.165.1.221
P407
P577
2000-07-01T00:00:00Z