Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines.
about
Targeting membrane-bound viral RNA synthesis reveals potent inhibition of diverse coronaviruses including the middle East respiratory syndrome virusRegulation of Stress Responses and Translational Control by CoronavirusSuppression of coronavirus replication by cyclophilin inhibitorsCoronavirus virulence genes with main focus on SARS-CoV envelope geneMiddle East respiratory syndrome: obstacles and prospects for vaccine developmentCoronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational RepressionMurine Coronavirus Mouse Hepatitis Virus Is Recognized by MDA5 and Induces Type I Interferon in Brain Macrophages/MicrogliaDynamics of coronavirus replication-transcription complexes.Structure of Alphacoronavirus Transmissible Gastroenteritis Virus nsp1 Has Implications for Coronavirus nsp1 Function and EvolutionInfluenza A Virus Protein PA-X Contributes to Viral Growth and Suppression of the Host Antiviral and Immune ResponsesThe replicase gene of avian coronavirus infectious bronchitis virus is a determinant of pathogenicityA systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections.Coronaviruses post-SARS: update on replication and pathogenesis.Immunization with an attenuated severe acute respiratory syndrome coronavirus deleted in E protein protects against lethal respiratory disease.Mechanisms of severe acute respiratory syndrome pathogenesis and innate immunomodulation.Pathogenesis of murine coronavirus in the central nervous system.Accessory protein 5a is a major antagonist of the antiviral action of interferon against murine coronavirus.Porcine epidemic diarrhea virus nucleocapsid protein antagonizes beta interferon production by sequestering the interaction between IRF3 and TBK1.Dependence of coronavirus RNA replication on an NH2-terminal partial nonstructural protein 1 in cis.The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitorsSARS coronavirus nsp1 protein induces template-dependent endonucleolytic cleavage of mRNAs: viral mRNAs are resistant to nsp1-induced RNA cleavageDendritic cell-specific antigen delivery by coronavirus vaccine vectors induces long-lasting protective antiviral and antitumor immunity.Autocrine interferon priming in macrophages but not dendritic cells results in enhanced cytokine and chemokine production after coronavirus infectionAlphacoronavirus transmissible gastroenteritis virus nsp1 protein suppresses protein translation in mammalian cells and in cell-free HeLa cell extracts but not in rabbit reticulocyte lysateMurine coronavirus ubiquitin-like domain is important for papain-like protease stability and viral pathogenesis.Coronaviruses: an overview of their replication and pathogenesis.Attenuation of mouse hepatitis virus by deletion of the LLRKxGxKG region of Nsp1.Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling.The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitisDendritic cell-specific delivery of Flt3L by coronavirus vectors secures induction of therapeutic antitumor immunitySARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex.Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.Cell-type-specific type I interferon antagonism influences organ tropism of murine coronavirusThe nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU.Dissection of amino-terminal functional domains of murine coronavirus nonstructural protein 3.Coronavirus nonstructural protein 1: Common and distinct functions in the regulation of host and viral gene expression.T helper cell- and CD40-dependent germline IgM prevents chronic virus-induced demyelinating diseaseGenetic evidence of a long-range RNA-RNA interaction between the genomic 5' untranslated region and the nonstructural protein 1 coding region in murine and bovine coronavirusesNonstructural protein 11 (nsp11) of porcine reproductive and respiratory syndrome virus (PRRSV) promotes PRRSV infection in MARC-145 cells.Middle East Respiratory Syndrome Coronavirus nsp1 Inhibits Host Gene Expression by Selectively Targeting mRNAs Transcribed in the Nucleus while Sparing mRNAs of Cytoplasmic Origin
P2860
Q21131361-1FFBC245-9FC6-4754-86D4-5C1C65DDCBBDQ26744222-256D4E51-8DB6-43DA-B571-CA1BFB2B4EBDQ26825245-BA96F1AC-D913-4762-8913-B902FB5FB3EAQ26827561-51D9F8DC-1249-4501-BC90-9FC9476444C0Q27013314-21541AFE-E68C-473F-98FC-76C5A4736CDCQ27485749-B199E5FF-097A-4F84-912E-412A0A7B4E94Q27487033-E12A797C-368D-4056-A9E8-5169595DC08BQ27490851-1D3729CD-EA3A-4EA4-BE68-1C5037F7AE8BQ27675608-1882BFA1-8B6C-4947-BCB4-5F087BA6AE2FQ30373511-EC1142E4-562A-4638-AD32-5BBA96BFDA5FQ33509514-C1E100C1-92ED-422E-B2D8-805DA30E2034Q33641434-1A578747-58A5-4649-BC12-F119172B7B5BQ33694361-84FB0EDE-8D53-4676-BC22-0D50CBB9BF6AQ33695621-5FDF3D52-DCAD-4D79-A13B-ECD8FA169C7FQ34014960-DEB4264B-EF2A-47AA-8DC3-2F7EC6C7FAA5Q34039962-617F4F40-6013-4AEC-B3BC-E86B52E73C02Q34046020-354BC0FE-FE77-4722-8C00-0EC197A70329Q34059146-39360B79-464A-4F72-B992-2FB85D5B4A5AQ34059202-1960BB28-B7B5-4929-B29C-DBFBACB1CEA6Q34064211-017B8C73-AFA2-4A47-AC07-199CEAA2AE60Q34102763-3EC1EF07-1251-437B-A2A4-D8BD481CAC7FQ34128906-44ADA455-CE7B-441B-B3AA-B78FEA012DA3Q34210525-B2DFA181-8D97-4BBD-B281-140628338A0FQ34457778-8C019928-8FA9-4704-9926-192A1F5250D2Q34463574-950B31F1-4F10-4E93-8621-0FB31C541DAEQ34464697-F968B3B3-5E0C-4B50-9F1D-1B221F9B5BC5Q34674709-52BD420D-1AAC-4762-824A-81F9B6A5F38BQ34712064-22465A34-2D17-435C-A62D-E4E6E9ECA21AQ34991394-3AACC18A-CE68-4DC3-AD37-D62875B19DA5Q35060537-216A7964-E2F0-4E98-8924-0D819A7B8945Q35119171-2F19565C-B86E-4ED0-A0DD-F258833351B6Q35239001-2C098123-12B1-4500-9EF4-CE91D6A1E9A4Q35382471-A3827731-C156-4540-97A7-86293E6DC3D1Q35488034-4282F230-2ED7-44FC-A95D-934B105AF892Q35641218-FFD3B426-8740-49F2-AD22-FCD0CB3A377FQ35648811-C86BF093-92B9-4A8C-870F-644801369485Q35708880-9E45ADF3-7EE3-4863-AAB6-709A83C15C8EQ35868051-CF8CE879-C8D5-4CAD-B2CA-F181F6981E94Q36042751-2E58E347-CA38-44DA-B659-7AA52C82A0B2Q36208133-91E47733-F303-47F9-BE7A-344EB2ABC54A
P2860
Coronavirus non-structural protein 1 is a major pathogenicity factor: implications for the rational design of coronavirus vaccines.
description
2007 nî lūn-bûn
@nan
2007 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@ast
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@en
type
label
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@ast
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@en
prefLabel
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@ast
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@en
P2093
P2860
P50
P1433
P1476
Coronavirus non-structural pro ...... esign of coronavirus vaccines.
@en
P2093
Gjon Blakqori
Luisa Cervantes-Barragán
Thomas Kuri
P2860
P356
10.1371/JOURNAL.PPAT.0030109
P577
2007-08-01T00:00:00Z