An ancient genetic link between vertebrate mitochondrial fatty acid synthesis and RNA processing.
about
Mammalian ACSF3 protein is a malonyl-CoA synthetase that supplies the chain extender units for mitochondrial fatty acid synthesisCompromised mitochondrial fatty acid synthesis in transgenic mice results in defective protein lipoylation and energy disequilibriumLipoic acid synthesis and attachment in yeast mitochondria.Heterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZIdentification of a novel mycobacterial 3-hydroxyacyl-thioester dehydratase, HtdZ (Rv0130), by functional complementation in yeastFunction of heterologous Mycobacterium tuberculosis InhA, a type 2 fatty acid synthase enzyme involved in extending C20 fatty acids to C60-to-C90 mycolic acids, during de novo lipoic acid synthesis in Saccharomyces cerevisiaeA C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductaseMyocardial overexpression of Mecr, a gene of mitochondrial FAS II leads to cardiac dysfunction in mouseExpression and evolution of the non-canonically translated yeast mitochondrial acetyl-CoA carboxylase Hfa1pOxygen and glucose deprivation induces widespread alterations in mRNA translation within 20 minutesDeath of a dogma: eukaryotic mRNAs can code for more than one protein.Intersection of RNA processing and the type II fatty acid synthesis pathway in yeast mitochondria.Down-regulation of mitochondrial acyl carrier protein in mammalian cells compromises protein lipoylation and respiratory complex I and results in cell death.Mitochondrial fatty acid synthesis type II: more than just fatty acids.Current understanding of fatty acid biosynthesis and the acyl carrier protein.Lipoic acid biosynthesis defects.Discovery and Characterization of the 3-Hydroxyacyl-ACP Dehydratase Component of the Plant Mitochondrial Fatty Acid Synthase System.Identification of the Leishmania major proteins LmjF07.0430, LmjF07.0440, and LmjF27.2440 as components of fatty acid synthase II.Genome-wide computational identification of bicistronic mRNA in humans.The 3-hydroxyacyl-ACP dehydratase of mitochondrial fatty acid synthesis in Trypanosoma brucei.RPP14 (HTD2) dehydrates 3HA-CoA to t2E-CoARecognition of the polycistronic nature of human genes is critical to understanding the genotype-phenotype relationship.
P2860
Q24322897-D3E39573-19FA-44F0-A845-9DADE9B3D0ABQ27314874-BF5237F9-252A-4F4C-A63F-AAD46DF45121Q27934157-6EFDD95B-DFE4-4190-BE73-9780A57E5190Q28486330-56721E6B-FAC7-44A0-8C42-74A59F74E68DQ28486477-105DF2C5-367B-4C62-9C06-6EF516422DE8Q28487264-47373581-6E89-4A64-A215-59B546925DA3Q30895955-6F0FA3D5-80CD-4095-86D5-9987705C2D6BQ33445584-5638E0EF-1468-4FEF-B76D-E865640953B7Q34681337-64D05681-ACC8-49B5-AB0B-432E1B821ACCQ35622581-2D886610-72B2-4511-A496-C55110930312Q36443272-3C75536C-DA71-489F-9EA0-80D88DC7AE71Q36949735-E0BEA45D-E17B-4B55-A584-2E3F4ECA155AQ37160918-C01D8822-4F00-4DC8-A852-B075F7A3A778Q37333233-11B72676-96C2-4415-81B6-0A072ABA0143Q37775996-B5566C2D-ACD2-431B-9C5D-A11FB40ECC64Q38207913-6E2BE983-95DF-4AC0-ACEA-D86E4C070114Q38959394-961AD08F-9D1F-4911-AE4F-C2E2456C19C9Q42084175-043B10DB-2C03-45E2-9655-2AF77697C0C1Q42666044-D3E10F41-22B9-482E-BAF2-20B1C782E4F4Q46766158-F96585B8-6ABC-4F3F-BA09-2C399BE7080FQ50293488-ACA51B3C-D676-4883-AC8E-B26BA83C8150Q52601702-0793CE48-DF37-4FB6-859C-DCA70667EF8B
P2860
An ancient genetic link between vertebrate mitochondrial fatty acid synthesis and RNA processing.
description
2007 nî lūn-bûn
@nan
2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
An ancient genetic link betwee ...... synthesis and RNA processing.
@ast
An ancient genetic link betwee ...... synthesis and RNA processing.
@en
An ancient genetic link betwee ...... synthesis and RNA processing.
@nl
type
label
An ancient genetic link betwee ...... synthesis and RNA processing.
@ast
An ancient genetic link betwee ...... synthesis and RNA processing.
@en
An ancient genetic link betwee ...... synthesis and RNA processing.
@nl
prefLabel
An ancient genetic link betwee ...... synthesis and RNA processing.
@ast
An ancient genetic link betwee ...... synthesis and RNA processing.
@en
An ancient genetic link betwee ...... synthesis and RNA processing.
@nl
P2093
P356
P1433
P1476
An ancient genetic link betwee ...... d synthesis and RNA processing
@en
P2093
Alexander J Kastaniotis
Carol L Dieckmann
Helmut Pospiech
Ilkka J Miinalainen
Kaija J Autio
Melissa S Schonauer
P304
P356
10.1096/FJ.07-8986
P407
P577
2007-09-26T00:00:00Z