The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionizati
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An association analysis of Alzheimer disease candidate genes detects an ancestral risk haplotype clade in ACE and putative multilocus association between ACE, A2M, and LRRTM3.ACE variants and association with brain Aβ levels in Alzheimer's diseaseInterplay of histidine residues of the Alzheimer's disease Aβ peptide governs its Zn-induced oligomerization.Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice.Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme.Evidence of endothelial dysfunction in the development of Alzheimer's disease: Is Alzheimer's a vascular disorder?Angiotensins and Alzheimer's disease: a bench to bedside overviewThe use of mass spectrometry to study amyloid-β peptides.Review: mass spectrometry in Russia.Aβ degradation or cerebral perfusion? Divergent effects of multifunctional enzymes.Angiotensin-converting enzyme levels and activity in Alzheimer's disease: differences in brain and CSF ACE and association with ACE1 genotypes.Angiotensin II-inhibition: effect on Alzheimer's pathology in the aged triple transgenic mouse.Angiotensin II-inhibiting drugs have no effect on intraneuronal Aβ or oligomeric Aβ levels in a triple transgenic mouse model of Alzheimer's disease.Minimal Zn(2+) binding site of amyloid-β.Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells.Molecular dynamics simulation and molecular docking studies of Angiotensin converting enzyme with inhibitor lisinopril and amyloid Beta Peptide.acn-1, a C. elegans homologue of ACE, genetically interacts with the let-7 microRNA and other heterochronic genes.N-domain of angiotensin-converting enzyme hydrolyzes human and rat amyloid-β(1-16) peptides as arginine specific endopeptidase potentially enhancing risk of Alzheimer's disease.Peripherally applied synthetic peptide isoAsp7-Aβ(1-42) triggers cerebral β-amyloidosis.The Coming of Age of the Angiotensin Hypothesis in Alzheimer's Disease: Progress Toward Disease Prevention and Treatment?
P2860
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P2860
The N-domain of angiotensin-converting enzyme specifically hydrolyzes the Arg-5-His-6 bond of Alzheimer's Abeta-(1-16) peptide and its isoAsp-7 analogue with different efficiency as evidenced by quantitative matrix-assisted laser desorption/ionizati
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
The N-domain of angiotensin-co ...... s-6 bond of Alzheimer's Abeta-
@nl
The N-domain of angiotensin-co ...... sted laser desorption/ionizati
@ast
The N-domain of angiotensin-co ...... sted laser desorption/ionizati
@en
type
label
The N-domain of angiotensin-co ...... s-6 bond of Alzheimer's Abeta-
@nl
The N-domain of angiotensin-co ...... sted laser desorption/ionizati
@ast
The N-domain of angiotensin-co ...... sted laser desorption/ionizati
@en
prefLabel
The N-domain of angiotensin-co ...... s-6 bond of Alzheimer's Abeta-
@nl
The N-domain of angiotensin-co ...... sted laser desorption/ionizati
@ast
The N-domain of angiotensin-co ...... sted laser desorption/ionizati
@en
P2093
P356
P1476
The N-domain of angiotensin-co ...... me-of-flight mass spectrometry
@en
P2093
Alexander A Makarov
Elena V Kugaevskaya
Igor A Popov
Ilya Yu Toropygin
Olga A Mirgorodskaya
Yulia E Elisseeva
Yuri P Kozmin
P304
P356
10.1002/RCM.3357
P577
2008-01-01T00:00:00Z