Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
about
Toward a magic or imaginary bullet? Ligands for drug targeting to cancer cells: principles, hopes, and challengesAsparagine beta-hydroxylation stabilizes the ankyrin repeat domain foldThe Contribution of Entropy, Enthalpy, and Hydrophobic Desolvation to Cooperativity in Repeat-Protein FoldingStructural and functional analysis of phosphorylation-specific binders of the kinase ERK from designed ankyrin repeat protein librariesDevelopment of a generic adenovirus delivery system based on structure-guided design of bispecific trimeric DARPin adaptersDesign of a binding scaffold based on variable lymphocyte receptors of jawless vertebrates by module engineeringStructure-based optimization of designed Armadillo-repeat proteinsDesign, construction, and characterization of a second-generation DARPin library with reduced hydrophobicitySelection of Specific Protein Binders for Pre-Defined Targets from an Optimized Library of Artificial Helicoidal Repeat Proteins (alphaRep)Adhiron: a stable and versatile peptide display scaffold for molecular recognition applicationsTolerance of the archaeal Sac7d scaffold protein to alternative library designs: characterization of anti-immunoglobulin G AffitinsDiscrete kinetic models from funneled energy landscape simulationsAmyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer diseaseDirect observation of parallel folding pathways revealed using a symmetric repeat protein system.Crystal structures of designed armadillo repeat proteins: implications of construct design and crystallization conditions on overall structure.Capturing the mechanical unfolding pathway of a large protein with coiled-coil probes.Analysis of repeat-protein folding using nearest-neighbor statistical mechanical modelsAn introduction to critical points for biophysicists; observations of compositional heterogeneity in lipid membranesFull reconstruction of a vectorial protein folding pathway by atomic force microscopy and molecular dynamics simulations.The energy landscapes of repeat-containing proteins: topology, cooperativity, and the folding funnels of one-dimensional architectures.Selection and characterization of DARPins specific for the neurotensin receptor 1A versatile palindromic amphipathic repeat coding sequence horizontally distributed among diverse bacterial and eucaryotic microbes.Functional β-propeller lectins by tandem duplications of repetitive units.Her2-specific multivalent adapters confer designed tropism to adenovirus for gene targetingMechanical unfolding of an ankyrin repeat protein.A rapid, site-selective and efficient route to the dual modification of DARPins.Highly potent VEGF-A-antagonistic DARPins as anti-angiogenic agents for topical and intravitreal applications.Peptide aptamers: development and applications.Complex energy landscape of a giant repeat protein.Mass discrimination in high-mass MALDI-MS.A disorder-induced domino-like destabilization mechanism governs the folding and functional dynamics of the repeat protein IκBαProteasomal degradation from internal sites favors partial proteolysis via remote domain stabilization.StaRProtein, a web server for prediction of the stability of repeat proteins.Highly polarized C-terminal transition state of the leucine-rich repeat domain of PP32 is governed by local stability.Capturing coevolutionary signals inrepeat proteins.Mechanical anisotropy of ankyrin repeatsMutation of conserved histidines alters tertiary structure and nanomechanics of consensus ankyrin repeats.Protein catalyzed capture agents with tailored performance for in vitro and in vivo applications.Modulation of folding kinetics of repeat proteins: interplay between intra- and interdomain interactions.Designed protein reveals structural determinants of extreme kinetic stability
P2860
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P2860
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@ast
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@en
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@nl
type
label
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@ast
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@en
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@nl
prefLabel
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@ast
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@en
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins.
@nl
P50
P1476
Folding and unfolding mechanism of highly stable full-consensus ankyrin repeat proteins
@en
P2093
Manca Kenig
Svava K Wetzel
P304
P356
10.1016/J.JMB.2007.11.046
P577
2007-11-22T00:00:00Z