Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).
about
The Novel Small Molecule Inhibitor, OSU-T315, Suppresses Vestibular Schwannoma and Meningioma Growth by Inhibiting PDK2 Function in the AKT Pathway ActivationAdhesion rings surround invadopodia and promote maturation.Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastomaThe function of integrin-linked kinase in normal and activated stellate cells: implications for fibrogenesis in wound healingSuppression of Her2/neu expression through ILK inhibition is regulated by a pathway involving TWIST and YB-1Functional Role of mTORC2 versus Integrin-Linked Kinase in Mediating Ser473-Akt Phosphorylation in PTEN-Negative Prostate and Breast Cancer Cell Lines.Validating the use of a luciferase labeled breast cancer cell line, MDA435LCC6, as a means to monitor tumor progression and to assess the therapeutic activity of an established anticancer drug, docetaxel (Dt) alone or in combination with the ILK inhRegulation of mitotic cytoskeleton dynamics and cytokinesis by integrin-linked kinase in retinoblastoma cells.Antiangiogenic therapy for glioma.MicroRNA-542-3p Suppresses Tumor Cell Invasion via Targeting AKT Pathway in Human Astrocytoma.Using Pharmacokinetic Profiles and Digital Quantification of Stained Tissue Microarrays as a Medium-Throughput, Quantitative Method for Measuring the Kinetics of Early Signaling Changes Following Integrin-Linked Kinase Inhibition in an In Vivo ModelJNK1 determines the oncogenic or tumor-suppressive activity of the integrin-linked kinase in human rhabdomyosarcomaQLT0267, a small molecule inhibitor targeting integrin-linked kinase (ILK), and docetaxel can combine to produce synergistic interactions linked to enhanced cytotoxicity, reductions in P-AKT levels, altered F-actin architecture and improved treatmenDifferential sensitivity of human glioblastoma LN18 (PTEN-positive) and A172 (PTEN-negative) cells to Taxol for apoptosis.Role of Akt in human malignant glioma: from oncogenesis to tumor aggressiveness.Characterization of matrix metalloproteinase-2 and -9, ADAM-10 and N-cadherin expression in human glioblastoma multiforme.A novel role of ribonuclease inhibitor in regulation of epithelial-to-mesenchymal transition and ILK signaling pathway in bladder cancer cells.The importance of integrin-linked kinase in the regulation of bladder cancer invasion.β1 integrin: an emerging player in the modulation of tumorigenesis and response to therapy.MicroRNA-542-3p inhibits oral squamous cell carcinoma progression by inhibiting ILK/TGF-β1/Smad2/3 signalingInterest of integrins targeting in glioblastoma according to tumor heterogeneity and cancer stem cell paradigm: an update.Integrin-linked kinase inhibition attenuates permeability of the streptozotocin-induced diabetic rat retina.Inhibition of high glucose-induced VEGF and ICAM-1 expression in human retinal pigment epithelium cells by targeting ILK with small interference RNA.The Small Molecule Inhibitor QLT-0267 Decreases the Production of Fibrin-Induced Inflammatory Cytokines and Prevents Post-Surgical Peritoneal Adhesions.
P2860
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P2860
Suppression of VEGF secretion and changes in glioblastoma multiforme microenvironment by inhibition of integrin-linked kinase (ILK).
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Suppression of VEGF secretion ...... integrin-linked kinase (ILK).
@ast
Suppression of VEGF secretion ...... integrin-linked kinase (ILK).
@en
Suppression of VEGF secretion ...... tion of integrin-linked kinase
@nl
type
label
Suppression of VEGF secretion ...... integrin-linked kinase (ILK).
@ast
Suppression of VEGF secretion ...... integrin-linked kinase (ILK).
@en
Suppression of VEGF secretion ...... tion of integrin-linked kinase
@nl
prefLabel
Suppression of VEGF secretion ...... integrin-linked kinase (ILK).
@ast
Suppression of VEGF secretion ...... integrin-linked kinase (ILK).
@en
Suppression of VEGF secretion ...... tion of integrin-linked kinase
@nl
P2093
P1476
Suppression of VEGF secretion ...... f integrin-linked kinase (ILK)
@en
P2093
Alastair H Kyle
Andrew I Minchinton
Ashish Rajput
B Thiessen
David Huntsman
Donald Yapp
Jessica Kalra
P356
10.1158/1535-7163.MCT-07-0329
P577
2008-01-01T00:00:00Z