Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children. - Wikidata - awgldk - TriplyDB

Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

http://www.wikidata.org/entity/Q33319552

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Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria The evolutionary consequences of blood-stage vaccination on the rodent malaria Plasmodium chabaudi Adenovirus-5-vectored P. falciparum vaccine expressing CSP and AMA1. Part B: safety, immunogenicity and protective efficacy of the CSP component High antibody titer against apical membrane antigen-1 is required to protect against malaria in the Aotus model Humoral immune response to mixed PfAMA1 alleles; multivalent PfAMA1 vaccines induce broad specificity.Phase 1 trial of AMA1-C1/Alhydrogel plus CPG 7909: an asexual blood-stage vaccine for Plasmodium falciparum malaria Safety and immunogenicity of an AMA1 malaria vaccine in Malian children: results of a phase 1 randomized controlled trial.A randomized and controlled Phase 1 study of the safety and immunogenicity of the AMA1-C1/Alhydrogel + CPG 7909 vaccine for Plasmodium falciparum malaria in semi-immune Malian adults.Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults.Immunization with the Malaria Diversity-Covering Blood-Stage Vaccine Candidate Plasmodium falciparum Apical Membrane Antigen 1 DiCo in Complex with Its Natural Ligand PfRon2 Does Not Improve the In Vitro Efficacy.Recombinant complement receptor 2 radiolabeled with [99mTc(CO)3]+: a potential new radiopharmaceutical for imaging activated complement Non-apical membrane antigen 1 (AMA1) IgGs from Malian children interfere with functional activity of AMA1 IgGs as judged by growth inhibition assay.Impact on malaria parasite multiplication rates in infected volunteers of the protein-in-adjuvant vaccine AMA1-C1/Alhydrogel+CPG 7909.Lack of allele-specific efficacy of a bivalent AMA1 malaria vaccine Identification and localization of minimal MHC-restricted CD8+ T cell epitopes within the Plasmodium falciparum AMA1 protein Advances and challenges in malaria vaccine development.Comparing the understanding of subjects receiving a candidate malaria vaccine in the United States and Mali Limited antigenic diversity of Plasmodium falciparum apical membrane antigen 1 supports the development of effective multi-allele vaccines.Preclinical vaccine study of Plasmodium vivax circumsporozoite protein derived-synthetic polypeptides formulated in montanide ISA 720 and montanide ISA 51 adjuvants.Anaemia in a phase 2 study of a blood stage falciparum malaria vaccine Immunological responses against Plasmodium falciparum Apical Membrane Antigen 1 vaccines vary depending on the population immunized Blood stage vaccines for Plasmodium falciparum: current status and the way forward.Promoting good clinical laboratory practices and laboratory accreditation to support clinical trials in sub-Saharan Africa.Malaria vaccines and their potential role in the elimination of malaria.Short report: elevated levels of alanine aminotransferase and hepatitis A in the context of a pediatric malaria vaccine trial in a village in Mali.Phase 1 randomized controlled trial to evaluate the safety and immunogenicity of recombinant Pichia pastoris-expressed Plasmodium falciparum apical membrane antigen 1 (PfAMA1-FVO [25-545]) in healthy Malian adults in Bandiagara Anti-apical-membrane-antigen-1 antibody is more effective than anti-42-kilodalton-merozoite-surface-protein-1 antibody in inhibiting plasmodium falciparum growth, as determined by the in vitro growth inhibition assay.Safety and Immunogenicity of EBA-175 RII-NG Malaria Vaccine Administered Intramuscularly in Semi-Immune Adults: A Phase 1, Double-Blinded Placebo Controlled Dosage Escalation Study.A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali Approaches to malaria vaccine development using the retrospectroscope.A Phase 1 study of the blood-stage malaria vaccine candidate AMA1-C1/Alhydrogel with CPG 7909, using two different formulations and dosing intervals Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach.

P2860

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P2860

Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

http://www.wikidata.org/entity/Q33319552

description

2008 nî lūn-bûn

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2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած

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2008 թվականի փետրվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Phase 1 study of a combination AMA1 blood stage malaria vaccine in Malian children.

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Beh Kamate

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Gregory E D Mullen

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Mady Sissoko

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Mark Pierce

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Mohamed Balla Niambelé

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Mounirou Baby

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Moussa Sogoba

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P2860

Safety and reactogenicity of an MSP-1 malaria vaccine candidate: a randomized phase Ib dose-escalation trial in Kenyan children.

Impact of a Plasmodium falciparum AMA1 vaccine on antibody responses in adult Malians

Phase 1 clinical trial of apical membrane antigen 1: an asexual blood-stage vaccine for Plasmodium falciparum malaria

Immunization with parasite-derived apical membrane antigen 1 or passive immunization with a specific monoclonal antibody protects BALB/c mice against lethal Plasmodium yoelii yoelii YM blood-stage infection.

In vitro studies with recombinant Plasmodium falciparum apical membrane antigen 1 (AMA1): production and activity of an AMA1 vaccine and generation of a multiallelic response

Vaccination of monkeys with recombinant Plasmodium falciparum apical membrane antigen 1 confers protection against blood-stage malaria

Protective immune responses to apical membrane antigen 1 of Plasmodium chabaudi involve recognition of strain-specific epitopes

A review of human vaccine research and development: malaria.

Malaria vaccines: are we getting closer?

Geographical structure of diversity and differences between symptomatic and asymptomatic infections for Plasmodium falciparum vaccine candidate AMA1.

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