Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN
about
MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN)"Rules of Engagement" of Protein-Glycoconjugate Interactions: A Molecular View Achievable by using NMR Spectroscopy and Molecular ModelingRecent strategies targeting HIV glycans in vaccine designDesigning synthetic vaccines for HIVGlycotherapy: new advances inspire a reemergence of glycans in medicineAntibody 2G12 Recognizes Di-Mannose Equivalently in Domain- and Nondomain-Exchanged Forms but Only Binds the HIV-1 Glycan Shield if Domain ExchangedA nonself sugar mimic of the HIV glycan shield shows enhanced antigenicityA Potent and Broad Neutralizing Antibody Recognizes and Penetrates the HIV Glycan ShieldBroad neutralization coverage of HIV by multiple highly potent antibodiesMicroscale electroporation: challenges and perspectives for clinical applications.Virus-like glycodendrinanoparticles displaying quasi-equivalent nested polyvalency upon glycoprotein platforms potently block viral infectionGRP78 knockdown enhances apoptosis via the down-regulation of oxidative stress and Akt pathway after epirubicin treatment in colon cancer DLD-1 cells.Broadly neutralizing human anti-HIV antibody 2G12 is effective in protection against mucosal SHIV challenge even at low serum neutralizing titersA Broadly Neutralizing Antibody Targets the Dynamic HIV Envelope Trimer Apex via a Long, Rigidified, and Anionic β-Hairpin Structure.Vaccine Elicitation of High Mannose-Dependent Neutralizing Antibodies against the V3-Glycan Broadly Neutralizing Epitope in Nonhuman PrimatesMultivalent benzoboroxole functionalized polymers as gp120 glycan targeted microbicide entry inhibitors.Antibodies against Manalpha1,2-Manalpha1,2-Man oligosaccharide structures recognize envelope glycoproteins from HIV-1 and SIV strainsEnvelope glycans of immunodeficiency virions are almost entirely oligomannose antigens.A general glycomimetic strategy yields non-carbohydrate inhibitors of DC-SIGN.Effects of neighboring glycans on antibody-carbohydrate interaction.Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds.Synthetic carbohydrate antigens for HIV vaccine design.Rational antibody-based HIV-1 vaccine design: current approaches and future directionsSelection of a synthetic glycan oligomer from a library of DNA-templated fragments against DC-SIGN and inhibition of HIV gp120 binding to dendritic cells.Analysis of carbohydrates and glycoconjugates by matrix-assisted laser desorption/ionization mass spectrometry: an update for 2007-2008.Envelope deglycosylation enhances antigenicity of HIV-1 gp41 epitopes for both broad neutralizing antibodies and their unmutated ancestor antibodies.Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infectionsMultivalent glycocluster design through directed evolution.Carbohydrate-based vaccines with a glycolipid adjuvant for breast cancerConvergent assembly and surface modification of multifunctional dendrimers by three consecutive click reactions.High sensitive detection of carbohydrate binding proteins in an ELISA-solid phase assay based on multivalent glyconanoparticles.Directed evolution of multivalent glycopeptides tightly recognized by HIV antibody 2G12.Perorally active nanomicellar formulation of quercetin in the treatment of lung cancerPresentation Modality of Glycoconjugates Modulates Dendritic Cell Phenotype.High-mannose glycan-dependent epitopes are frequently targeted in broad neutralizing antibody responses during human immunodeficiency virus type 1 infection.Quinoxalinone Inhibitors of the Lectin DC-SIGN.Antibodies elicited by yeast glycoproteins recognize HIV-1 virions and potently neutralize virions with high mannose N-glycans.Understanding carbohydrate-protein interactions using homologous supramolecular chiral Ru(ii)-glyconanoclusters.Noncarbohydrate glycomimetics and glycoprotein surrogates as DC-SIGN antagonists and agonists.2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies.
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P2860
Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@ast
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@en
Targeting the carbohydrates on ...... nal antibody 2G12 and DC-SIGN.
@nl
type
label
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@ast
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@en
Targeting the carbohydrates on ...... nal antibody 2G12 and DC-SIGN.
@nl
prefLabel
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@ast
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@en
Targeting the carbohydrates on ...... nal antibody 2G12 and DC-SIGN.
@nl
P2093
P2860
P356
P1476
Targeting the carbohydrates on ...... onal antibody 2G12 and DC-SIGN
@en
P2093
Chi-Huey Wong
Dennis R Burton
Rena D Astronomo
Shie-Liang Hsieh
Tsui-Ling Hsu
P2860
P304
P356
10.1073/PNAS.0712326105
P407
P577
2008-02-29T00:00:00Z