A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities.
about
γ-Tocotrienol induces paraptosis-like cell death in human colon carcinoma SW620 cellsTargeting Wnt/β-catenin pathway in hepatocellular carcinoma treatmentTargeting the Wnt/β-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lines with FH535Wnt Drug Discovery: Weaving Through the Screens, Patents and Clinical TrialsPhytochemicals attenuating aberrant activation of β-catenin in cancer cellsE-cadherin-downregulation and RECK-upregulation are coupled in the non-malignant epithelial cell line MCF10A but not in multiple carcinoma-derived cell lines.Inhibition of canonical WNT signaling attenuates human leiomyoma cell growthFH535 Suppresses Osteosarcoma Growth In Vitro and Inhibits Wnt Signaling through TankyrasesEvolving role of Sorafenib in the management of hepatocellular carcinoma.PP2A inhibitors suppress migration and growth of PANC-1 pancreatic cancer cells through inhibition on the Wnt/β-catenin pathway by phosphorylation and degradation of β-catenin.Silymarin targets β-catenin signaling in blocking migration/invasion of human melanoma cells.Glucosylceramide synthase upregulates MDR1 expression in the regulation of cancer drug resistance through cSrc and beta-catenin signaling.FH535 inhibited migration and growth of breast cancer cells.Small molecule modulators of Wnt/β-catenin signaling.Honokiol inhibits non-small cell lung cancer cell migration by targeting PGE₂-mediated activation of β-catenin signalingCanonical Wnt signaling activity in early stages of chick lung development.Influence of five potential anticancer drugs on wnt pathway and cell survival in human biliary tract cancer cellsTranscriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.FH535 inhibited metastasis and growth of pancreatic cancer cells.Meiotic competent human germ cell-like cells derived from human embryonic stem cells induced by BMP4/WNT3A signaling and OCT4/EpCAM (epithelial cell adhesion molecule) selection.N-Aryl benzenesulfonamide inhibitors of [3H]-thymidine incorporation and β-catenin signaling in human hepatocyte-derived Huh-7 carcinoma cells.Small molecule-mediated up-regulation of microRNA targeting a key cell death modulator BNIP3 improves cardiac function following ischemic injury.Ceramide glycosylation by glucosylceramide synthase selectively maintains the properties of breast cancer stem cells.A dual function for canonical Wnt/β-catenin signaling in the developing mammalian cochlea.β-Catenin and peroxisome proliferator-activated receptor-δ coordinate dynamic chromatin loops for the transcription of vascular endothelial growth factor A gene in colon cancer cells.Nuclear translocation of MEK1 triggers a complex T cell response through the corepressor silencing mediator of retinoid and thyroid hormone receptor.Evidence of a role for CD44 and cell adhesion in mediating resistance to lenalidomide in multiple myeloma: therapeutic implications.PPARs and Mitochondrial Metabolism: From NAFLD to HCC.WNT/β-Catenin signaling pathway regulates non-tumorigenesis of human embryonic stem cells co-cultured with human umbilical cord mesenchymal stem cells.Wnt/beta-catenin signaling in glioma.Differentiation of progenitors in the liver: a matter of local choiceHerbal Medicine Offered as an Initiative Therapeutic Option for the Management of Hepatocellular Carcinoma.Wnt signaling as potential therapeutic target in lung cancer.Wnt signaling inhibitor FH535 selectively inhibits cell proliferation and potentiates imatinib-induced apoptosis in myeloid leukemia cell lines.Clipping the Wings of Glioblastoma: Modulation of WNT as a Novel Therapeutic Strategy.Hepatic cancer stem cell marker granulin-epithelin precursor and β-catenin expression associate with recurrence in hepatocellular carcinoma.WNT/β-catenin signaling regulates cigarette smoke-induced airway inflammation via the PPARδ/p38 pathway.Transforming growth factor-β-dependent Wnt secretion controls myofibroblast formation and myocardial fibrosis progression in experimental autoimmune myocarditis.FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R.Anoikis of colon carcinoma cells triggered by β-catenin loss can be enhanced by tumor necrosis factor receptor 1 antagonists.
P2860
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P2860
A small-molecule inhibitor of Tcf/beta-catenin signaling down-regulates PPARgamma and PPARdelta activities.
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@ast
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@en
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@nl
type
label
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@ast
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@en
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@nl
prefLabel
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@ast
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@en
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@nl
P1476
A small-molecule inhibitor of ...... amma and PPARdelta activities.
@en
P2093
Julian A Simon
Shlomo Handeli
P304
P356
10.1158/1535-7163.MCT-07-2063
P577
2008-03-01T00:00:00Z