Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics
about
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responsesA systems view of host defenseCharacterizing dynamic changes in the human blood transcriptional networkThe landscape of host transcriptional response programs commonly perturbed by bacterial pathogens: towards host-oriented broad-spectrum drug targetsA model of the circadian clock in the cyanobacterium Cyanothece sp. ATCC 51142Gene regulatory network modeling via global optimization of high-order dynamic Bayesian networkSystems biology of innate immunityHuman Dendritic Cell Response Signatures Distinguish 1918, Pandemic, and Seasonal H1N1 Influenza Viruses.Reconstruction of regulatory networks through temporal enrichment profiling and its application to H1N1 influenza viral infection.Motif prediction to distinguish LPS-stimulated pro-inflammatory vs. antibacterial macrophage genes.Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia.Identifying Cell Type-Specific Transcription Factors by Integrating ChIP-seq and eQTL Data-Application to Monocyte Gene RegulationDigital gene expression signatures for maize development.Taming dataUsing cell fate attractors to uncover transcriptional regulation of HL60 neutrophil differentiation.A joint finite mixture model for clustering genes from independent Gaussian and beta distributed dataCombined genome-wide expression profiling and targeted RNA interference in primary mouse macrophages reveals perturbation of transcriptional networks associated with interferon signallingFunctional characterization of transcription factor motifs using cross-species comparison across large evolutionary distances.Dissecting interferon-induced transcriptional programs in human peripheral blood cells.CNBP acts as a key transcriptional regulator of sustained expression of interleukin-6.Transcriptional regulation of gene expression clusters in motor neurons following spinal cord injuryIdentification of the key differential transcriptional responses of human whole blood following TLR2 or TLR4 ligation in-vitro.Genome-wide histone acetylation data improve prediction of mammalian transcription factor binding sites.Cardiovascular networks: systems-based approaches to cardiovascular diseaseIntegrating multiple evidence sources to predict transcription factor binding in the human genome.Antiviral response dictated by choreographed cascade of transcription factors.Controlling the response: predictive modeling of a highly central, pathogen-targeted core response module in macrophage activation.Systems-level analysis of innate immunity.Inflammatory gene regulatory networks in amnion cells following cytokine stimulation: translational systems approach to modeling human parturition.LPS regulates SOCS2 transcription in a type I interferon dependent autocrine-paracrine loop.Combined chromatin and expression analysis reveals specific regulatory mechanisms within cytokine genes in the macrophage early immune responseIdentification and validation of Ifit1 as an important innate immune bottleneckA systems biology approach to understanding atherosclerosis.A novel unbiased measure for motif co-occurrence predicts combinatorial regulation of transcriptionTranscriptome-based network analysis reveals a spectrum model of human macrophage activation.Incorporating time-delays in S-System model for reverse engineering genetic networksInflammatory links between obesity and metabolic disease.Metabolic labeling of RNA uncovers principles of RNA production and degradation dynamics in mammalian cellsDe novo characterization of the Anthurium transcriptome and analysis of its digital gene expression under cold stress.Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses.
P2860
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P2860
Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics
description
2008 nî lūn-bûn
@nan
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Uncovering a macrophage transc ...... anning and expression dynamics
@ast
Uncovering a macrophage transc ...... anning and expression dynamics
@en
Uncovering a macrophage transc ...... nning and expression dynamics.
@nl
type
label
Uncovering a macrophage transc ...... anning and expression dynamics
@ast
Uncovering a macrophage transc ...... anning and expression dynamics
@en
Uncovering a macrophage transc ...... nning and expression dynamics.
@nl
prefLabel
Uncovering a macrophage transc ...... anning and expression dynamics
@ast
Uncovering a macrophage transc ...... anning and expression dynamics
@en
Uncovering a macrophage transc ...... nning and expression dynamics.
@nl
P2093
P2860
P1476
Uncovering a macrophage transc ...... anning and expression dynamics
@en
P2093
Alan Aderem
Carrie D Johnson
Carrie M Rosenberger
Daniel E Zak
Elizabeth S Gold
Garnet Navarro
Jared C Roach
Kathleen A Kennedy
Mark Gilchrist
P2860
P304
P356
10.1371/JOURNAL.PCBI.1000021
P577
2008-03-21T00:00:00Z