Fragment approaches in structure-based drug discovery

Fragment approaches in structure-based drug discovery

Item
http://www.wikidata.org/entity/Q33329074
Non-peptidic cruzain inhibitors with trypanocidal activity discovered by virtual screening and in vitro assayHitting the target: fragment screening with acoustic in situ co-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes.Native MS: an 'ESI' way to support structure- and fragment-based drug discovery.Design of a fragment library that maximally represents available chemical space.Hit clustering can improve virtual fragment screening: CDK2 and PARP1 case studies.HTS by NMR of combinatorial libraries: a fragment-based approach to ligand discovery.Combined Use of Oligopeptides, Fragment Libraries, and Natural Compounds: A Comprehensive Approach To Sample the Druggability of Vascular Endothelial Growth Factor.Enhancing Drug Efficacy and Therapeutic Index through Cheminformatics-Based Selection of Small Molecule Binary Weapons That Improve Transporter-Mediated Targeting: A Cytotoxicity System Based on Gemcitabine.Discovery of novel antibacterials.Oncogenic protein interfaces: small molecules, big challenges.2,3-Dihydroxy-quinoxaline induces ATPase activity of Herpes Simplex Virus thymidine kinase.Current perspectives in fragment-based lead discovery (FBLD).PDK1 selectively phosphorylates Thr(308) on Akt and contributes to human platelet functional responses.
P2860

Fragment approaches in structure-based drug discovery

Item
http://www.wikidata.org/entity/Q33329074
description
2008 nî lūn-bûn
@nan
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Fragment approaches in structure-based drug discovery
@ast
Fragment approaches in structure-based drug discovery
@en
Fragment approaches in structure-based drug discovery.
@nl
type
label
Fragment approaches in structure-based drug discovery
@ast
Fragment approaches in structure-based drug discovery
@en
Fragment approaches in structure-based drug discovery.
@nl
prefLabel
Fragment approaches in structure-based drug discovery
@ast
Fragment approaches in structure-based drug discovery
@en
Fragment approaches in structure-based drug discovery.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932
P356
P1433
P1476
Fragment approaches in structure-based drug discovery
@en
P2093
P2860
P304
P31
P356
P433
P478
P577
P698
P932